James Keeler Department of Chemistry, University of Cambridge, UK
This text discusses the high-resolution NMR of liquid samples and concentrates exclusively on spin-half nuclei (mainly 1H and 13C). It is aimed at people who are familiar with the use of routine NMR for structure determination and who wish to deepen their understanding of just exactly how NMR experiments work. It demonstrates that in NMR it is possible, quite literally on the back of an envelope, to make exact predictions of the outcome of quite sophisticated experiments. The experiments chosen are likely to be encountered in the routine NMR of small to medium-sized molecules, but are also applicable to the study of large biomolecules, such as proteins and nucleic acids.
The book starts off at a gentle pace, working through some more-or-less familiar ideas, and then elaborating these as the book progresses. Each chapter ends with exercises which are designed to assist in the understanding of the ideas presented and to grasp the underlying ideas.
Decided to read this cover to cover for once. Makes NMR concepts like pulse sequences much easier to understand, and connects basic math with the physics of the technique well.
I actually met James Keeler at a symposium a month or so ago, cool guy.
A little too complicated for students who are just beginning to understand the concepts of Nuclear Magnetic Resonance. For a book titled as "Understanding NMR spectroscopy", I think the book could have been written in a little more lucid language and with basic equations.
Very well explained, and fascinating. The math went over my head, especially since I was reading this on a deadline and lacked the quantum mechanics background to follow everything. I learned what I needed to, and the book would have taught me much more if I had given it the time.