Best friends Cara and Ana embark on another adventure with Cara's new husband Alexander and his brother Duncan. The four time travelers tour the Villa d'Agostino outside Modena, Italy only to find themselves transported to the year 1570. There, Cara is mistaken for her doppelganger ancestor Alessandra DiCelli who has run away. The four must find Alessandra while contending with a hostile household and a dangerous visitor from their past.