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El manual de las sustancias psicodélicas: Una guía práctica y revisión histórica, médica y farmacológica de las principales sustancias psicodélicas: ... ... to Psychedelics & More)

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Learn everything you need to know about psychedelics with this ultimate guide packed with information on popular psychedelic drugs like psilocybin, ketamine, MDMA, DMT and LSD—plus practical tips for microdosing and how to safely "trip"—from bestselling author Dr. Rick Strassman. Aprenda todo lo que necesita saber sobre las sustancias psicodélicas con esta guía definitiva repleta de información sobre drogas psicodélicas populares como la psilocibina, la ketamina, el MDMA, la DMT y el LSD—además de consejos prácticos para la microdosificación y cómo “viajar” de forma segura— del autor best-seller Dr. Rick Strassman, quien ha estado al frente de la investigación sobre psicodélicos desde los años 60.Entering the world of psychedelic drugs can be challenging, and many aren’t sure where to start. As research continues to expand and legalization looms on the horizon for psychedelics like psilocybin, you may need a guide to navigate what psychedelics are, how they work, and their potential benefits and risks. The Psychedelic Handbook is a complete manual that is accessible to anyone with an interest in these “mind-manifesting” substances. Packed with information on psilocybin, LSD, DMT/ayahuasca, mescaline/peyote, ketamine, MDMA, ibogaine, 5-methoxy-DMT (“the toad”), and Salvia divinorum/salvinorin A, this book is your ultimate reference for understanding the science and history of psychedelics; discovering their potential to treat depression, PTSD, substance abuse, and other disorders, as well as to increase wellness, creativity, and meditation; learning how to safely trip and explaining what we know about microdosing; and recognizing and caring for negative reactions to psychedelics. Clinical research psychiatrist, founding figure of the American psychedelic research renaissance, and best-selling author of The Spirit Molecule, Dr. Rick Strassman shares his experience and perspectives as neither advocate nor foe of psychedelics in order to help readers understand the effects of these remarkable drugs.

222 pages, Kindle Edition

Published December 5, 2023

112 people are currently reading
897 people want to read

About the author

Rick Strassman

11 books360 followers
Rick Strassman is a clinical associate professor of psychiatry at the University of New Mexico School of Medicine. He trained as a medical doctor specialized in psychiatry with a fellowship in clinical psychopharmacology research and holds degrees from Stanford University and Albert Einstein College of Medicine of Yeshiva University.
He has held a fellowship in clinical psychopharmacology research at the University of California San Diego and was Professor of Psychiatry for eleven years at the University of New Mexico.
After twenty years of intermission, Strassman was the first person in the United States to undertake human research with psychedelic, hallucinogenic, or entheogenic substances with his research on DMT.
He is the author of the well-known book "DMT: The Spirit Molecule" which summarizes his academic research into DMT.

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5 stars
129 (47%)
4 stars
93 (34%)
3 stars
40 (14%)
2 stars
6 (2%)
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1 (<1%)
Displaying 1 - 28 of 28 reviews
Profile Image for Vicky Mo.
10 reviews
June 12, 2023
Exactly what I was looking for!! Practical information as well as basic science (although could've been a bit more in depth) behind most classic and some additional substances. Perfect to receive an overview. Ready to dive deep into the more specific literature now!
Profile Image for Amaia ✡.
161 reviews35 followers
August 24, 2023
A very handy summary of the scientific literature about psychedelic studies to date curated by a psychiatrist. There’s also an introduction to every molecule with pharmacological,
botanical and historical data. Very useful and so promising for therapy in so many psychiatric disorders.
Profile Image for Liquidlasagna.
2,910 reviews105 followers
July 30, 2024

the wild Amazone

Generic one page underwhelming explanations for psychedelics. More of a thumbnail explanation guide for "dummies'
Profile Image for Floris Wolswijk.
70 reviews9 followers
July 25, 2022
This book is a perfect introduction to those new to psychedelics, covering both practical aspects, background information on research and the different psychedelics. The neutral, yet engaging, tone of Strassman (one with extensive experience in the field) is refreshing and trustworthy.
Profile Image for Elia Flores Lastra.
65 reviews
December 23, 2022
A pretty good book, however, it is hard to follow all the chemist part of it, once you pass that section of the book it is easy to follow, I thought it was going be a bit more “hippie” but it turns out to be a very professional book. I like that it shows mostly the con´s about using any of these psychedelics. It gives you enough information in order to go ahead with the “trip” or think it twice before you do it. Definitely a book that everyone should read so we can help someone who is struggling with a problem (depression, PTSD, substance abuse, and other disorders ) that may be solve with no so traditional “medicine”. It is amazing all the things that some of these “drugs” can do. Definitely we need to continue with the studies of these psychedelics as they might be the solutions of many social problems.
Profile Image for Rachel Dick Plonka.
186 reviews16 followers
September 19, 2023
This book was so good I immediately emailed the author upon finishing to express my gratitude.

It is clear, balanced, succinct, and explains complex concepts in a clear and concise way. The author’s background speaks for itself. Dr. Strassman is most well known for discovering the molecule melatonin. He also ran the first clinical trials on psychedelics since research was shut down in the 60s by the Controlled Substances Act.

I particularly love that he wove in not only Buddhist and modern spiritual concepts, but ancient Jewish teachings as well, including the philosophy of Maimonides and teachings from the Bible.

This book is short, to the point, and well worth the read if you are at all curious about the power of psychedelics.
Profile Image for Zac.
82 reviews64 followers
November 25, 2022
Psychedelics are neat. I'll write a more thorough review when I don't have to leave for work in 10 minutes. Probably.
Profile Image for Anna.
204 reviews34 followers
October 15, 2023
Very well-written. Perhaps a bit basic for advanced users, but a good overview nevertheless
303 reviews9 followers
Read
October 7, 2024
Pharmacological calvanism - you should inly take drugs to treat illness. Not for pleasure, or spiritual purpose

The most striking effect of psychedelics is that they seem more real than real

A “true hallucination” is believing what you are experiencing is objective reality and this rarely happens on a psychedelic.

The term spiritual may concern the idea of “god”, or even “sacred/profane”.

Spiritual experiences can be mystical/unitive (like eastern religion) or “interactive relational” (like the biblical tradition)

A psychedelics effect results from who gives them, who takes them, and why (set/setting)

Grof- they are non specific amplifiers of unconscious mental material

They )by def - manifest and disclose the minds contents

U can withdrawals from a drug but not be addicted to it because you dont crave it

Daily dose of classic psychedelics reduces their effects. With the exception if dmt. And 5meo gives greater responses to the same dose

Psychological risk of use is low with care to set/setting/contraindications. The rate of psychosis for more than 24 hrs is lower than the general population.

77% of psychedelic users reported flashbacks, particularly from a bad experience

Connectivity and entropy can last for days and weeks after a psilocybin experience

Psychedelics stimulate the growth of new neurons and increase neuroplasticity

Psychedelics are powerful anti inflammatory drugs

People who have drug induced mystical experiences have increased acceptance, openess, and compassion - but this may not always be a good things

Peyote use 5000 yrs
San pedro use 3000 yrs
Mushroom use 10,000 yrs
Toad venom 3000 yrs(?)

There is the dmt world and there is this one. You interact with one or the other depending on how much dmt is in the brain. Its endogenous presence regulates your reality

Aya produces rapid benefits to people with anxiety and depression

Nasal ketamine has onset in 3-5 min and lasts 30-60 min

Salvia os the most potent naturally occurring psychedelic. And can produce “true hallucinations”.

The trip begins when i decide to take it - leo zeff

Self knowledge, Some knowledge of the terrain, and overall health,0 should be a prerequisite

Its possible for example, that u may want to replay past traumas in order to generate more self-pity

If you resist the trip experience, letting go benefits you. Slow breathing helps you. Relaxing your body helps you. Holding a hand might help. Pushing agains someone for a time might help

Be wary of interacting w beings who seem menacing. Do not allow them to force you to do anything

For bad trips:
Empathize
Decrease sensory input
Nonsexual physical contact
Move outside to fresh air
Try milk, vitamin c, niacin
Valium or klonopin are mild and safe
Thorazine, halodol are strong
2 reviews
June 18, 2024
As a fellow healthcare professional, I expected more from this book. There is minimal info detailing the significant drug interactions with psychedelics and antidepressants -the author acknowledges the interaction in just one paragraph of the entire book. Any serotonin-effecting antidepressant blunts the effects of psychedelics, and there have been many articles published prior to the publication of this 2022 book. According to the CDC, greater than 15% of adults have taken an antidepressant in the last 30 days.

Pros:
-professional, accurate, well written, good intentions on educating the public
-emphasis on set and setting and preparation for tripping
-other concerns with taking psychedelics including unscrupulous practitioners
-thorough list of additional resources and readings provided

Cons:
-no details on drug interactions, which greatly impact the effectiveness and safety of psychedelics
-why is there so much history content, book title is Practical Guide
-NO pictures or diagrams whatsoever, would be particularly helpful for sections on the brain and mind
-format and layout need improving

Bottom line:
The book has potential but needs some improvements and additional information. Currently, there are better resources out there including reputable websites, journal articles, and other books.
4 reviews1 follower
November 20, 2023
Rick Strassman provides an objective and well researched take on many common psychedelic substances and gives an expert account of their history, uses, risks, mechanisms, and legal status. He discusses their scientific, religious, and spiritual backgrounds and addresses some of the broader philosophical points questions that they raise.

It is a must-read for anyone interested not only in psychedelics, but also for those interested in therapy and mental health. I would encourage anyone with preconceived ideas about psychedelics to read this book.
Profile Image for Artiom Karsiuk.
215 reviews14 followers
July 5, 2024
First of all, drugs are swell. Secondly, this is a HANDBOOK, meaning - if you plan to dabble in drugs (like some shady people I may or may not know; or am or may not am) - you can find all of the relevant information: dose depending on your goals for the trip, safety precautions, expected common effects, health concerns and etc. Brought to you by [an overqualified author] a Medical Doctor. So if you ever planned to try this LSD thing and were wondering "Could that break my brain?" or already dropped a tad too much acid and think "Lupen bimber folda monker", this book may be precious.
40 reviews
November 25, 2024
Super interesting book that touches on the cutting edge uses of psychedelics in treating neurological conditions while also addressing what we do and do not know about them and why. Talks about the history and applications of the substances and how they will be used in the future. Well written book that was a change of pace of my usual style. Favorite part was the talks on PTSD treatment and I would recommend to anyone interested in the field of neurology/psychology.
Profile Image for Mo Tahmasbi.
34 reviews1 follower
August 31, 2025
Whether you’re for or against psychedelics, this book has something for you. Rick Strassman approaches the subject with real objectivity.

I’ve listened to both of his Joe Rogan episodes, and now I’m diving straight into DMT: The Spirit Molecule.

I literally want to read and hear everything this guy has to say.

The man’s a guru.
8 reviews
January 14, 2024
Un ottimo libro per iniziare a scoprire e capire il mondo delle sostanze psichedeliche e la loro importanza.
Scrittura asciutta, chiara ed essenziale. Utile anche a chi ha già studiato precedentemente i temi trattati.
2 reviews
January 24, 2024
Ugh this book should be called what you already know about psychedelics…it was so boring! I was hoping to learn something new but I did not find anything new in the 55% of the book I read it was just a rehash of everything I already knew. Too bad I loved Rick Strassmans book about DMT.
Profile Image for Kelsie B.
46 reviews
April 23, 2024
Not bad it teaches you about the history of different drugs and at the end ish if the book it gives you a "how to" section!
Profile Image for Christopher Altes.
28 reviews
Read
June 15, 2024
This was very dry and helped me understand some of what I've heard and seen in the past.

It was interesting to try to unpack all of the baggage.
Profile Image for Dottie.
15 reviews1 follower
May 2, 2025
If you were to read only one book on psychedelic substances, this is the one!
13 reviews
August 4, 2025
It was really fun and interesting to read.
Profile Image for Sophie Reyno.
18 reviews
December 8, 2024
Rick Strassman covers all the basic information you need to enter the world of psychedelics while keeping the information interesting and palatable. A really fun read but incredibly informative. It is evident through descriptions of his career and the depth of his knowledge that he has decades of valuable experience. Read it!!
Profile Image for David Wagner.
707 reviews23 followers
February 21, 2025
Most of it is quite practical, promotes reasonable harm reduction approaches (including very clear "you should not do that if you do not have a very good reason" and "people might abuse you") and some basic orientation in history and potential of the practice. Also clearly steers away from Grof-like mysticism and treats the substances as a tool (very often not a great one), not as a goal in itself.
Profile Image for Tristan Barrett.
6 reviews
December 28, 2022
Was a good explanation and break down of different psychedelics and how set and setting play an immense role for the trip, was a bit textbook-like in some portions but overall well written and helpful to widen my understanding of the topic
Profile Image for Gabrielle.
4 reviews
May 21, 2024
Super informative book, great place to start educating yourself on psychedelic substances
Displaying 1 - 28 of 28 reviews

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