Sequence is about a reality where Earth is on a collision course with destruction, with massive storms bringing horrific conditions all across the planet, animals and insects disappearing, other things dying out en masse. there may be no way to save our planet from whatever is ravaging it, but there may be a way to send the reality of humanity out into the stars using the Pandora system -- which is siphoning off memories from its users while making them re-live those memories as part of its programming.
The high concept plays into a lot of the novel, but one of the issues I had with this book is that the high concept is just the "how" to get the story the writer actually wants to tell. It's a tale about two people, about how hard life can be and how much we try to leave the bad in the past even as it's wreaking havoc on our present. Our main characters are married and are working on Pandora -- each one facing all the bad things in their past that led them to where they are today. Some are things they did, some things they did to others. And it's honestly a really fast, really engaging read. The marriage of mythology and science in the worlds of the two characters added an extra dimension, especially if you were familiar with the myths that many people draw their names from (the book does eventually explain most of them, but I think it adds something to know from the start).
This is one of those stories that I loved reading, but am not sure I'll go back to. It can be a tough read at times emotionally -- there are some seriously bad things in both characters backstories that get re-lived. And at the end, it felt like one story -- the emotional one -- wrapped up nicely but the broader one just kind of was left open. I'm reasonably sure this was intentional, but it didn't leave me feeling satisfied with the reading experience on some level. And yeah, some books are like that intentionally, and some people like that sort of thing. It just unfortunately didn't work for me.
Still, overall this was a solid read and one I'd recommend if the concept sounds interesting to you.