Pakistani Fazid Taqvi learns his family was killed by a U.S. drone. The Americans apologize. It was a mistake, they said, the unfortunate "collateral damage" of war.
Enraged, Taqvi vows to show the United States what real "collateral damage" looks like. A brilliant microbiologist, he creates a unique bioweapon by manipulating the DNA of a deadly virus and devises an ingenious method to deploy it.
To exact his revenge against the United States, he needs help. Iran agrees to assist . . . but at a price. He must first use it against Israel.
Israeli intelligence, the Mossad, uncovers the plot and assigns their best agent, assassin Eric Burns, to prevent the attack. But, before they can stop the Pakistani, he launches the weapon.
Burns discovers how the bioweapon is spread, and suspects he may be infected. While hunting the terrorist in America, his worst fears are realized when he begins to show symptoms of the deadly virus.
A chance discovery that Taqvi created an antidote sends Burns on a life-and-death race against time to find the cure before he, and tens of thousands of others, become “collateral damage”.