AN UPDATING OF HIS BOOK, “THE FIFTH MIRACLE”
Paul Charles William Davies (born 1946) is an English physicist, writer and broadcaster, who is currently a professor at Arizona State University as well as the Director of BEYOND: Center for Fundamental Concepts in Science.
He wrote in the Preface to this 2003 revision, “This book focuses on the origin of life. The problem of ‘biogenesis’ divides up into the when, the where and the how. We shall see that scientists have a pretty good idea of when life first established itself on Earth. As far as the where part… the evidence points increasingly to a hot, subsurface setting… but whether the transformation from non-life to life took place on Earth, or Mars, or both, remains an open question. The how part of the puzzle is undoubtedly the toughest to solve…” (Pg. xvii-xviii)
He continues, “When I set out to write this book I was convinced that science was close to wrapping up the mystery of life’s origin. The dramatic evidence for microbes living deep underground… promised to provide the ‘missing link’ between the prebiotic world of biochemical soups and the first primitive cells… Several recent books convey the confident message that life’s origin is not really so mysterious after al. However, I think they are wrong… I am now of the opinion that there remains a huge gulf in our understanding… we are a long way from understanding the how.” (Pg. xxiii-xxiv)
He explains, “Taking my cue from Francis Crick, and his reference to biogenesis being ‘almost a miracle,’ I called this book ‘The Fifth Miracle’ for its initial 1998 printing. The current revised edition is retitled ‘The Origin of Life’ to reflect more clearly its content. The work remains substantially unchanged, however; indeed, it proved to be remarkably prescient… I have updated the text here and there, and inserted notes to cover the recent developments.” (Pg. xxv)
He observes, “How does one go about assembling a scientific account of the genesis of life? At first sight the task appears hopeless… If we had to rely on rock fossils along, the task… would indeed be formidable. Fortunately there is another line of evidence altogether… By studying how the modern cell operates, we can glimpse remnants of ancestral life at work… Even with such biochemical clues, the task of reconstruction would still be largely guesswork were it not for the recent discovery of… microbes that inhabit weird and extreme environments.” (Pg. 7-8)
He suggests that “we will not be able to trace the origin of biological information to the operation of local physical forces and laws. In particular, the oft-repeated claim that life is written into the laws of physics cannot be true if those laws are restricted to the normal sort… we must seek the origin of biological information in some sort of global context. This… may involve some non-local type of physical law as yet unrecognized by science, that explicitly entangles the dynamics of information with the dynamics of matter.” (Pg. 44-45)
He acknowledges, “Though it is very unlikely that we will ever find out exactly what happened, we might be able to deduce a plausible chemical pathway leading from simple chemicals to life… However, in our present state of ignorance, all we can hope for are a few pointers to the key chemical steps that may have been involved.” (Pg. 59)
He points out, “Alas, the euphoria over the Miller-Urey experiment turned out to be somewhat premature, for a variety of reasons. First, geologists no longer think that the early atmosphere resembled the gas mixture in Miller’s flask… A second reason … is that amino acids are not, in fact, all that hard to make anyway. Many successful variants on the original Chicago set-up have been tried… It turns out that making amino acids is a cinch… There is also a conceptual reason why the Miller-Urey experiment is no longer accorded the status it once had. It is a serious mistake to regard the road to life as a uniform highway down which a coup of chemicals is inexorably conveyed by the passage of time… a collection of amino acids is a long, long way from the sort of large, specialized molecules such as proteins that life requires.” (Pg. 65-66)
He states, “There is a more fundamental reason why the random self-assembly of proteins seems a non-starter. This has to do with … the particular order in which the amino acids link together. Proteins… are very specific amino acid sequences that have specialized chemical properties needed for life. However, the number of alternative permutations available to a mixture of amino acids is super-astronomical… Hitting the right one by accident would be no mean feat.” (Pg. 69)
He argues, “Some people feel that something as basic as our own existence can’t be put down to a chemical quirk, and that … the word ‘accident’ is a cop-out… The Earth appears to be a typical planet around a typical star in a typical galaxy. So why should life on Earth not also be typical? Unfortunately this argument will not wash. Our own existence must be the exception to the rule that what we observe is unexceptional. If there is only one planet in the universe with life, it has to be ours! Obviously we won’t find ourselves living on a lifeless planet, by definition. So Earth will not be a randomly selected planet… because we have selected it by our very existence.” (Pg. 74)
He explains, “In recent years, attempts have been made to build small and simple replicator molecules in the lab…. However, these experiments do not demonstrate molecular evolution in nature. They have yet to show that the sort of small replicators that have been … fabricated in the laboratory will form spontaneously under plausible prebiotic conditions… In short, nobody has a clue whether naturally occurring mini-replicators are even possible, let alone whether they have got what it takes to evolve successfully.” (Pg. 113)
He asserts, “I think there almost certainly WAS life on mars 3.6 billion years ago. The reason I am so confident in this belief is not because I am sure life emerged from a primordial Martian soup (though it may have been), but because the planets are not, and never have been, quarantines from each other.” (Pg. 203)
He observes, “Of course, it isn’t necessary for the success of the panspermia process for each and every space-faring microbe to survive interstellar voyages. It demands only a single bacterium to make it alive and find a suitable planet to call home. Life might even be disseminated around the cosmos if microbes are officially dead on arrival… Entertaining though these ideas of ‘naked’ panspermia may be, I find it hard to take the theory seriously. While… [it] is theoretically possible, the odds are heavily against it. It is most unlikely to be going on systematically all across the Galaxy… However, there IS a way for microbes to journey from one planet to another in relative safety, and that is for them to hitch a ride in a meteorite.” (Pg. 207-208)
He adds, “the Murchison meteorite proves one thing at least. There are objects in space loaded with just the sort of organic compounds needed for life to get started. It doesn’t require a primordial soup on Earth to synthesize the building blocks of life. These substances can fall from the sky, ready-made.” (Pg. 210) He continues, “Not only was Mars a better place for life to start, it could also have proved a favorable location for it to evolve… If life arose independently on Earth and Mars, then a Martian microbe reaching Earth might arrive to find organisms already well ensconced… The Martians might get gobbled up by Earthly bacteria as soon as they arrived.” (Pg. 218-219)
He speculates, “There is thus a sort of hardware-software entanglement in quantum mechanics. Information … has downward causative power. So here is a mainstream physical theory that has information at its heart, which it tangles with matter in an intimate way. Furthermore, the interatomic forces that form biological molecules like proteins and nucleic acids are indeed quantum mechanical in nature. Could some sort of quantum organizing process be just what is needed to explain the origin of informational macromolecules?” (Pg. 243-244) He adds, “I concede that the ideas I have skimmed over in this section are highly conjectural, but the very fact that the problem of biogenesis prompts such speculation underscores just how stubborn a mystery it is.” (Pg. 245)
He states, “If evolution is nothing but a lottery… there is little reason why life should go beyond the level of microbes, and no expectation whatever that it will advance obligingly towards intelligence and consciousness, still less develop humanoid characteristics. We should then be forced to agree with [Jacques] Monod’s melancholy conclusion that ‘Man… is alone in the unfeeling immensity of the universe, out of which he has emerged only by chance.’ Only if there is more to it than chance, only if nature has an ingeniously built-in bias towards life and mind, would we expect to see anything like the developmental thrust that has occurred on Earth repeated on other planets… On the other hand, there is an alternative view… It is the vision of a self-organizing and self-complexifying universe, governed by ingenious laws that encourage matter to evolve towards life and consciousness. A universe in which the emergence of thinking being is a fundamental and integral part of the overall scheme of things. A universe in which we are not alone.” (Pg. 255-256)
This book will interest those studying ‘origin of life’ theories.