Computational and Statistical Approaches to Genomics

by Wei Zhang (Editor), Ilya Shmulevich, Zhang Wei Zhang (Editor)

At the beginning of the post-sequencing era, biology must work with the enormous amounts of quantitative data being amassed and must render complex problems in mathematical terms, with all of the computational effort that entails. This phenomenon is perhaps best exemplified by the interdisciplinary scientific activity caused by the advent of high-throughput cDNA microarray technology, which facilitates large-scale surveys of gene expression. Biologists must now work together with engineers, statisticians, computer scientists, and other specialists, in order to attain a holistic understanding of the complex relationship between genes within the genome and uncover genetic function and regulation. This text aims to help researchers deal with contemporary genomic challenges. Topics covered include: - overviews of the role of supercomputers in genomics research, the existing challenges and directions in image processing for microarray technology, and web-based tools for microarray data analysis;

344 pages, Hardcover

First published March 28, 2002

About the author

Zhang Wei (simplified Chinese: 张炜; traditional Chinese: 張煒; pinyin: Zhāng Wěi; born November 1955) is a Chinese author. He was born in China's northern province of Shandong. He graduated from the Chinese Department at Yantai Normal College in 1980. Three years later, he became a member of Chinese Writers Association, an organization for which he has served as chairman and deputy chairman of the Shandong branch. He is best known for his novels The Ancient Ship and September's Fable. In 2011 Zhang won the Mao Dun Literature Prize, the highest national literary award, for On the Plateau, a 10-volume work that took a decade to write.

(from Wikipedia)