My take: the reality of the world and all its relations defies our "summing it up". It is not a sum, it is not calculable, because the weights of its "components", which are mutually constituted and constitutive, keep changing. They change in ways we cannot altogether anticipate (though they are subject to patterns and constraints), and cannot therefore "bank on". What we can do is adumbrate on the basis of where we are at currently and how we got here, in good faith, with as much information and honesty as we can muster, but knowing that our deliberations are provisional and liable to further consideration as matters unfold. New modes with new weights can emerge or be revealed; existing nodes can shift weights; old verities can become outmoded or require new articulation within the system. This constant readiness to renegotiate the balance within the system is what exercising responsibility means.
Therefore, it follows that learning about both (1) the information and relationships that constitute the system and (2) the ubiquity of contingency and provisionality as the ground of being/becoming [be(com)ing] are equally vital.