Females Are Mosaics: X Inactivation and Sex Differences in Disease

by Barbara R. Migeon

Women can be described as genetic mosaics because they have two distinctly different types of cells throughout their bodies. Unlike males, who have one X chromosome, females have two X chromosomes in every cell. Much has been written about the Y chromosome and its role in inducing maleness. This is the only book about the X chromosome as a key to female development and the role of X-related factors in the etiology of sex differences in human disease. This new edition reflects research advances from the six years since the widely praised first edition. New advances include knowledge of species differences in mammalian X inactivation processes and silencing of the inactive X chromosome.

328 pages, Hardcover

First published November 1, 2013

Reviews

[Keeley Dennett · Rating 3 out of 5]

apart from being structured both physically and literally strange, the book was alright. The content was okay but was highly repetitive and could have been a journal article rather than a 200 page book. Still found it interesting because dosage compensation and x inactivation is cool, but the book definitely had its flaws.