At the beginning of the twentieth century, the orphan train movement is in full effect, having run more than fifty years and transporting more than two hundred fifty thousand orphans from the streets of New York to the mid-west.
Fifteen-year-old Lonnie, his ten-year-old brother, Wallace, and eight-year-old sister, Peg, have been living on the streets of New York for the past year after their mother's death. Barely able to beg for enough money to eat, Wallace decides to take matters into his own hands against his and steal a gold watch. Unfortunately for Wallace, that watch belonged to Mr. Kelly, a leader of one of the five points gangs, and he has no intention of letting that go unpunished.
To avoid the wrath of Mr. Kelly, the children have no other option than to hop on the orphan train and head west. On the train, the siblings find that they’re not alone in their story of loss, heartache, and survival of a downtrodden life.