The sixth installment, and final book in the series, takes place during the video game of the same name. Claire Redfield, brother of former S.T.A.R.S. member Chris Redfield of RE 1/Umbrella Conspiracy, is now on the hunt for clues as to where Chris Redfield is. After the events of RE 2, she finds out that Chris has gone to Europe to take on the umbrella Corporation directly with other former S.T.A.R.S. members. During her investigation, in Paris, Claire is captured and sent to Rockfort Island. Claire gets knocked out, and finally comes to after realizing that a T-Virus outbreak has occurred on the island. While dealing with more creatures, which have apparently been sent by a rogue organization, she runs into a fellow prisoner named Steve Burnside. They work together to try and escape the island, while dealing the psychotic Alfred Ashford, who cross dresses as his sister Alexia Ashford, and finally defeat him. Before dying, Alfred is able to awaken his sister from her 15 year hyper sleep. Injected with the T-Veronica Virus, counter virus to the affects of the T-Virus, she causes Claire and Steve to crash land in Antarctica. The story then shifts to that of Chris Redfield, notified about Claire's absence by Leon S. Kennedy from RE 2/City of The Dead, and Underworld. Along the way, Chris comes into conflict with Albert Wesker. A man whom was thought to have died during the events of RE 1/Umbrella Conspiracy, who is somehow alive and transformed by some virus that gives him superhuman abilities. As Chris finds Claire, things get worse with the loss of Steve infected by the T-Veronica Virus. Though he does fight against it in order to save Claire. The book ends with Chris and Claire watching Wesker take the body of Steve, after they have defeated a mutated Alexia Ashford, and leaving the facility.
The problem with video game to book adaptations is that the video games can change something just like that. So a major story deviation in the games takes place, and the reader can easily get lost. During the course of RE 1 Albert Wesker died in two ways, depending upon the character choices in the game. Either he gets killed by the Tyrant, or he dies from the chimera creatures found in the pump room. Those were the creatures that liked to hang on the ceiling, and swipe at you from above. Umbrella Conspiracy went mostly by the pump room ending. Barry Burton beats him in the head with his magnum, Wesker stumbles into the pump room and gets mauled by chimera. Looking for Wesker in the pump room lead to only seeing a headless body, in the video game. RE does not sugar coat violence.
SD Perry was able to make books based on RE 1-3. Code Veronica was published in 2001, the RE Code Veronica game came out in 2000. Within universe of the book series, Albert Wesker died after the events of Umbrella Conspiracy.
RE 1 had been released in 1996. Albert Wesker's death, as seen in the RE 1 and graphic novels based on RE 1, was considered cannon via the Tyrant killing him. So Perry went by that cannon for the longest time. Upon the re release, RE 1 for the Gamecube, things changed a tad. Originally, in the first RE 1, Albert Wesker just gets killed by the Tyrant. In the Nintendo Gamecube version, a scene was added since Albert Wesker appeared in RE Code Veronica. The remake of RE 1 showed Wesker injecting himself with a virus, and then dying by the hands of the Tyrant. With his "death" the virus took hold and transformed Wesker into the super human we see during the events of RE Code Veronica/Code Veronica.
So of course this book was not in sync with the game. Perry was still going by the original RE 1 cannon death of Albert Wesker. It didn't help matters with the RE 1 remake adding back story that wasn't present in the original RE 1. That was my main concern with this book. Other parts were solid.