Nucleic Acids

by Erwin Chargaff (Editor)

The Nucleic Acids, Volume III covers the significant progress in understanding the chemistry and biological importance of the nucleic acids.
This volume is composed of 12 chapters, and begins with an overview of the general principles of the determination of weight, shape, and dimension of large molecules in solution. These topics are followed by discussions on the photochemistry of nucleic acids and its constituents; chemical and enzymic synthesis of polynucleotides; and nucleic acid content and dynamics of bacterial viruses. The next chapters describe the biosynthesis of purine and pyrimidine nucleotides. A chapter examines the relationship of nucleic acid and protein synthesis through considering cell-free systems, particularly those derived from mammalian tissues. Another chapter looks into the protein biosynthesis in intact bacterial cells. The final chapters explore the nucleic acid metabolism, with a special emphasis on the effect of radiation on the process.
This book is of value to organic chemists and biochemists.

605 pages, ebook

First published January 1, 2012

About the author

Erwin Chargaff was an Austrian biochemist who was a professor of biochemistry at Columbia University medical school.
Chargaff proposed main rules in his lifetime related to DNA studies best known as Chargaff's Rules.