A pretty confused book, with six very uneven chapters. The chapters really aren't clearly connected to each other - it's not clear if the author is trying to make a sustained argument, or is opining about the modern history of science in general. What's more, some of his arguments are really poorly supported, or poorly laid out. What he takes to be a radical alternative to the Newtonian and Baconian perspectives on science, the "Jeffersonian Research Program", is not well explained, and it's not at all clear that it could not be subsumed under one of the two other programs.
I did come out of reading this with a greater understanding of the development of the American scientific tradition, though, as well as with an appreciation of some of the concerns of proponents of Enlightenment values, so this book was not a waste of time