This book essentially consists of highlights from Randy Cohen's New York Times Magazine column, "The Ethicist," with additional commentary by Cohen.
First and foremost, strange though it may be to say of a book on ethics, The Good, The Bad, and The Difference is a very entertaining read. That is the case mostly because Cohen is extremely witty and doesn't mind sacrificing a bit of deep ethical analysis for the sake of spinning off a sarcastic joke. It is also partly a result of the fact that some of the people who wrote in to "The Ethicist" presented some pretty ridiculous situations.
The book, then, is a fun read, at times a thought-provoking read, but not, perhaps, your best choice as a moral guidebook for your life. Even though I largely share Cohen's anti-establishment views, I couldn't entirely accept his casual willingness to let those personal biases color his ethical vision. Repeatedly, he gives those who wish to skirt the system his blessing if he feels the system itself is unjust. Certainly, a great many moralists and ethicists, notably Thoreau, encouraged disobedience of unjust rules. However, it must be remembered that when Thoreau refused to pay his taxes in protest of federal government actions, he did so openly and served jail time as a result. There is a big difference between open protest — and accepting the consequences of that protest — and sneakily dodging the rules. Cohen continually glosses over that distinction.
Overall, then, I recommend the book fairly highly, provided one takes it with a grain of salt, as I think Cohen himself would recommend. One more comment I feel compelled to add. In his introduction to the book, Cohen states that "If everyone were like Atticus Finch (of To Kill a Mockingbird), the south would still be segregated." He is referencing, of course, the fact that Finch did not actively fight segregation (at least not that we see in the novel). However, given how Finch raises his children, it is easy to see that if everyone really were like Finch, segregation most definitely would have died away, for no Atticus Finch would ever have been willing to enforce such laws. One must not be too quick to dismiss the profound influence of strongly moral people, even quiet and seemingly acquiescent ones.