This short book records the notes written by Edward Jenner in the 1790's, when he was working on vaccination against smallpox with a cowpox material. I needed to know how it all started. Edward Jenner was a great note keeper and that is why he was accredited the invention. It makes sense. The book introduces Sarah Nemes, the milkmaid whom he took cowpox material from and then injected it into a young boy James Phipps. It would seem Edward Jenner wasn't necessarily be the first to do this process but his study was large and listened to.