Dr. Betty Reaper is a University of Kentucky house physician as well as an instructor at the neighboring Case Western Reserve medical school in which she continues to teach a few days a month. As the end of her career approaches, she decides to begin a new career path as a prison physician full time with an office located in the infirmary. Sudden deaths begin to occur at the prison along with organ theft which is discovered at the funeral parlor prior to embalming. With the help of the FBI, she has to find justice for the inmates she took an oath to protect.