Two young and ambitious vampires, Ambrogio and Antonello, begin a life of crime in the time of prohibition. New York City is in a state of chaos as rival families, one controlled by an atrocious vampire and the other a power hungry werewolf, battle for ultimate supremacy. All those in the underworld must pick a side or perish. In the beginning of this series Ambrogio and Antonello struggle to protect their family and friends in their pursuit to evade the clutches of the established and much more powerful Dons.