How pathogens cause disease
The first thing to understand about this book is that it is a textbook and a difficult one. The difficulty for the beginning student or general reader is not a fault of the authors. Rather it is because medical microbiology itself is a daunting subject full of organisms that can only be seen fuzzily with an electron microscope, if at all, organisms involved in processes and behaviors that are foreign to our everyday experience. Add the fact that most of the material covered here is not part of a non-specialist curriculum either in high school or college, and effectively speaking the untrained reader is starting from scratch.
Well, why do that? First of all, because the material itself--how viruses, bacteria, fungi, and other infectious organisms enter the body, replicate, and cause disease--is fascinating and of immediate relevance to our lives. Second because (to my knowledge) there is little or nothing else available to the general reader that goes beyond a sketchy introduction to the subject. One is forced to read a text book. Fortunately this is a good one and it is thorough.
The text covers the range of infectious disease from viruses to tapeworms. The amount of technical information presented is daunting, and the sheer expanse of terminology a challenge (why is there no glossary?). The text is lavishly illustrated with photos and electron micrographs of the pathogens, as well as numerous schematic drawings showing how microorganisms cause disease, how they replicate, their chemical structure, their morphology, etc.
The instructional schematic drawings I found less valuable than the electron micrographs, but I suspect for the student of microbiology it might be the other way around.
What you'll get out of this handsome book depends on how much time and energy you are able to devote to it. I started reading this in the hope that I would, perhaps by osmosis, pick up some feel for life at the micron level, and I did. Obviously if I had been able to study the text with the help of an instructor, I would have learned a lot more.
--Dennis Littrell, author of “The World Is Not as We Think It Is”