Now this is a horror novel. This is what Steven King used to be, and has lost with recent, over-commercialized works. This is the kind of thing that will keep you up at night well after you've finished it, loaded with images that will stick with you for a long time.
At its most basic level, it's a well-worn plot, the same one used in a dozen Crichton works. It hasn't been really new since Frankenstein, and maybe not even then. Scientist creates something he doesn't fully understand, creation takes on life of its own and grows in unpredictable and "impossible" ways, scientist loses control, non-scientists have to save day from rogue creation. Just because you can doesn't mean you should, this is why we can't have nice things, etc. But Clements handles it in a way that is fresh and unpredictable, and just a little bit terrifying. He never lets you forget that this is a horror novel, and he keeps the pressure and the terror up throughout the book, building to an earth-shattering conclusion. People die, they die horribly, a lot, include characters that were firmly established and that you liked, and wouldn't have expected to die. When you thought he'd reached the outer limits of where he could safely go, that surely he couldn't go any further, and then--he does! But he manages to do it in a way that is organic to the story, that makes a terrible kind of sense, rather than just throwing something in because he wants to be shocking. I read and watch a lot of horror, and not much gets to me, but there was a scene near the end that turned my stomach. So word to the wise: this is well worth the read, but you have to have a very high tolerance for some very graphic things. If I were teaching a science and philosophy class, I'd try to make this required reading, but I'd probably get fired.
I would love to see this made into a movie. I actually checked for it, but unless it was made under another name, I can't find it. That's a shame--the visual images are stunning, but it's probably just as well. Hollywood would never get the plot right anyway.