The fundamental premise of Adam Thierer's book "Permissionless Innovation: The Continuing Case for Comprehensive Technological Freedom" is sound. It is important to avoid pre-emptive regulation that will discourage innovation. Thierer's additional suggestions of applying existing laws first and creating sunset clauses for regulations deemed absolutely necessary are also reasonable.
The book is well-researched and heavily cited, lending credibility to his claims, however less repetition and some additional examples early on would be helpful. It is important also to emphasize the degree to which regulation not only impedes innovation, but also creates a powerful incentive for existing market leaders to protect themselves from disruptive competition through lobbying. Licensed monopoly taxis vs. Uber, for example.
In reality, government regulation is not just problematic in terms of restricting new technologies, it also is used to pervert existing ones. This book suggests that governments should engage in education, but that is a scary prospect. I remember the food pyramids that were taught to me in government schools that encouraged a highly politicized, unhealthy balance of food groups. As the political influencers changed, the "official" recommendations for consumption also adjusted radically, though not necessarily in the interest of the common man.
In short, the general message of avoiding pre-emptive regulation based on worst-case scenarios is sound, but the book could more effectively use real examples like the Skype v. FWD to demonstrate their case. It should go further, however to underline how regulation is perverted by interest groups, both scaremongers such as Greenpeace and vested interests.
It may be beyond the purposes of the book, but it could also touch on the constitutionality of such regulations. By limiting national regulation per the Constitution, state regulations on innovation FORCE cost benefit analyses because if, for example, a state like New York restricts fracking, states such as North Dakota can profit from that choice by allowing it. Inter-state competition enforces regulatory due diligence. National regulation stifles regulatory competition. The emphasis should not only be on how government regulation dangerously reduces quality of life by impeding innovation, but how such government intervention is both immoral and unconstitutional.
Finally, it may be helpful to underline as well the risks of government involvement in innovation. When government sponsors research (e.g., Solyndra), foreign aid (e.g., Poverty Inc.), healthcare (e.g., ObamaCare), education (e.g., Common Core) or higher education research grants (e.g., Global Warming/Cooling hysteria), resources are diverted from more promising technologies and innovations.