In "The Stress Paradox", Sharon Horesh Bergquist redefines our understanding of stress by turning conventional wisdom on its head. Rather than treating all stress as a harmful force, the book explores the surprising idea that certain kinds of stress can actually enhance our physical health, emotional well-being, and mental performance. This concept is rooted in the biological principle of hormesis—a phenomenon in which small, manageable doses of stress stimulate the body’s repair mechanisms, resulting in increased resilience and strength. Instead of avoiding discomfort at all costs, Bergquist argues that embracing targeted, short-term challenges can transform how we age, feel, and function.
Much of what we associate with stress today—tight deadlines, overwhelming responsibilities, and constant stimulation—falls into the category of chronic stress, which does damage over time. However, Bergquist encourages us to distinguish this toxic variety from the kind that prompts growth and regeneration. Just as a muscle becomes stronger after being pushed during a workout, the cells in our body can also become more robust when they are exposed to specific stressors in moderation. This cellular-level stress—whether caused by certain foods, temperature shifts, or physical exertion—promotes healing, bolsters defenses, and helps prepare us for future hardships. The aim of the book is not to glorify suffering, but rather to advocate for intentional stress that leaves us better off.
This beneficial stress response is not a new discovery, but its deeper significance took time to be recognized. Back in the 1800s, German scientist Hugo Schulz observed that yeast cells exposed to low levels of disinfectants actually thrived rather than perished. Although this discovery seemed odd at the time, it laid the groundwork for what we now understand about hormesis. The idea that small stressors can promote health applies broadly—from immune function and metabolism to cognition and emotional resilience. Exposing the body to controlled challenges sets off an internal housekeeping process that rejuvenates cells, protects DNA, and enhances overall vitality. Bergquist emphasizes that our modern lifestyles, filled with ease and convenience, have stripped away these essential stressors, leaving us more vulnerable to chronic diseases.
One of the key ways to reintroduce good stress into our lives is through nutrition—specifically, by eating a wide range of plant-based foods rich in natural defense chemicals known as phytochemicals. Plants under environmental stress produce compounds that act like mild irritants when consumed, prompting our bodies to turn on internal defenses. These include antioxidant activity, DNA repair, and improved cellular metabolism. For example, resveratrol—found in grapes, berries, and red wine—stimulates protective proteins and genes that promote cellular cleanup and regeneration. Other compounds like sulforaphane from broccoli, allicin from garlic, and quercetin from fruits and tea each trigger specific repair and detoxification pathways in the body. Interestingly, plants that grow in more natural or organic conditions tend to develop higher levels of these protective chemicals, as they are exposed to more environmental stress. By simply broadening the variety of plant foods we eat, we can tap into this powerful system of stress-induced renewal.
The second strategy centers around fasting, a nutritional challenge that activates deep metabolic repair processes. When we go without food for extended periods, our insulin levels drop, and the body switches into fat-burning mode, using stored energy more efficiently. This state not only supports weight management but also reduces the risk of chronic conditions like diabetes and cardiovascular disease. Bergquist highlights time-restricted eating—specifically a 14-hour fasting window—as a practical and effective way to bring these benefits into daily life. This approach helps synchronize eating with the body’s natural circadian rhythm, encouraging better digestion, energy use, and hormonal balance. Even imperfect adherence can produce meaningful results, as the body is well-equipped to respond positively to periods of rest and repair.
Physical activity is another cornerstone of the hormesis model. Exercise is perhaps the most familiar example of beneficial stress—when we challenge our muscles and cardiovascular system, we set off a cascade of responses that strengthen the entire body. But the advantages of exercise extend far beyond physical strength. On a cellular level, movement enhances energy production by improving mitochondrial function, reduces inflammation, and supports brain health by increasing levels of growth factors like BDNF. These changes can help stave off mental fog, fatigue, and mood disorders. Bergquist advises a balanced fitness routine that includes steady-state activities along with short bursts of high-intensity training. The key is to push the body just enough to trigger adaptation without tipping into exhaustion. As always, recovery is essential; it’s during rest that the real rebuilding occurs.
Another source of healthy stress comes from exposure to natural temperature variations, which challenge the body’s ability to regulate itself. In our climate-controlled lives, we rarely experience the extremes that would have once been common. Yet short-term exposure to heat and cold can boost circulation, improve mood, and enhance insulin sensitivity. Cold exposure, for instance, activates stress hormones like noradrenaline, leading to sharper alertness and better focus, while also causing a surge in dopamine that lifts mood. Heat exposure, such as in saunas, mimics the effects of cardiovascular exercise and reduces inflammation. Research suggests that around an hour of heat and just over ten minutes of cold exposure per week—spread out across several days—can produce meaningful benefits. These practices are not about seeking discomfort for its own sake, but about leveraging the body’s built-in adaptation systems to improve health and resilience.
The final component in Bergquist’s protocol involves psychological stress—specifically, using manageable cognitive challenges to keep the brain engaged and adaptable. Not all mental stress is harmful. In fact, low to moderate levels of stress that we can control and that align with our goals can sharpen focus, boost motivation, and increase mental stamina. Facing unfamiliar situations, solving problems, or stepping into leadership roles can be mentally demanding in a way that promotes growth. These stressors activate neurotransmitters like dopamine and oxytocin that improve mood and strengthen social connections. As with physical stress, the benefits of mental stress come with boundaries. It’s critical to balance challenge with recovery through rest, sleep, and relaxation, allowing the mind to integrate gains and restore energy.
The overarching message of "The Stress Paradox" is that discomfort, when chosen wisely and applied in moderation, can be a potent tool for building lasting health and happiness. Each form of stress described in the book—nutritional, metabolic, physical, thermal, and cognitive—activates specific systems in the body that are designed to keep us resilient and thriving. In today’s environment of constant convenience, these beneficial stressors have become rare, and as a result, we may be losing the very strengths that once protected us. By deliberately reintroducing small, strategic challenges into our lives and honoring the body’s need to recover afterward, we can harness the power of stress as a force for healing and transformation.
In the end, Bergquist’s message is not about making life harder, but about making it more vital. The book presents a vision of health that is both modern and rooted in our evolutionary past—one that sees stress not as a threat to be avoided, but as a tool to be wielded. By embracing this new relationship with stress, we can cultivate a deeper form of well-being that leaves us not only longer-lived but also more energized, focused, and resilient in the face of life’s challenges.