The study of animal virus pathogenesis is an important and rapidly developing area, especially since the emergence of AIDS and the consequent increase in research activity. Because this work takes place at the interface between virology and immunology, understanding viral pathogenesis requires knowledge and use of techniques drawn from several disciplines. This book provides up-to-date coverage of the way that viral tropism, viral expression, and viral infectivity are assayed. It describes the identification of antiviral cytotoxic T cells, natural killer and free antibody responses. It also covers making vaccinia/viral cDNA for immunologic target recognition, and tissue and whole animal in situ hybridization.
Born in New York, NY; married; children: three. Education: University of Alabama, A.S., 1954; University of Maryland, M.D., 1961; advanced study at Johns Hopkins McCullom Pratt Institute of Biochemistry. Hobbies and other interests: Bird watching, fly fishing, body surfing, reading.
MEMBER: American Association of Physicians, American Society for Clinical Investigation, Scandinavian Society of Immunology (elected).
AWARDS, HONORS: Burroughs Wellcome Professorship Award, Medical Research Council; American Academy of Microbiology fellow; Cotzias Award, for contributions in research, 1986; Abraham Flexner Award, for contributions in biomedical research, 1988; Rous-Whipple Award, for contributions in experimental pathology, 1993; Biomedical Science Award, Karolinska Institute, for contributions in virus/autoimmune diseases, 1994; J. Allyn Taylor International Prize in Medicine, for contributions in virus-host interactions and viral pathogenesis, 1997; R.E. Dyer Lectureship and Directors Award, National Institutes of Health, for contributions in viral pathogenesis, 2000; Pioneer in NeuroVirology Award, International Society for NeuroVirology, 2003; elected to Institute of Medicine, National Academy of Sciences.