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The Menopause Brain: New Science Empowers Women to Navigate the Pivotal Transition with Knowledge and Confidence
The New York Times bestselling author of The XX Brain shows women how to navigate menopause successfully and come out the other side with an even better brain.
Menopause and perimenopause are still a black box to most doctors, leaving patients exasperated as they grapple with symptoms ranging from hot flashes to insomnia to brain fog. As a leading neuroscientist and women’s brain health specialist, Dr. Mosconi unravels these mysteries by revealing how menopause doesn’t just impact the ovaries—it’s a hormonal show in which the brain takes center stage.
The decline of the hormone estrogen during menopause influences everything from body temperature to mood to memory, potentially paving the way for cognitive decline later in life. To conquer these challenges successfully, Dr. Mosconi brings us the latest approaches—explaining the role of cutting-edge hormone replacement therapies like “designer estrogens,” hormonal contraception, and key lifestyle changes encompassing diet, exercise, self-care, and self-talk.
Best of all, Dr. Mosconi dispels the myth that menopause signifies an end, demonstrating that it’s actually a transition. Contrary to popular belief, if we know how to take care of ourselves during menopause, we can emerge with a renewed, enhanced brain—ushering in a meaningful and vibrant new chapter of life.
Menopause and perimenopause are still a black box to most doctors, leaving patients exasperated as they grapple with symptoms ranging from hot flashes to insomnia to brain fog. As a leading neuroscientist and women’s brain health specialist, Dr. Mosconi unravels these mysteries by revealing how menopause doesn’t just impact the ovaries—it’s a hormonal show in which the brain takes center stage.
The decline of the hormone estrogen during menopause influences everything from body temperature to mood to memory, potentially paving the way for cognitive decline later in life. To conquer these challenges successfully, Dr. Mosconi brings us the latest approaches—explaining the role of cutting-edge hormone replacement therapies like “designer estrogens,” hormonal contraception, and key lifestyle changes encompassing diet, exercise, self-care, and self-talk.
Best of all, Dr. Mosconi dispels the myth that menopause signifies an end, demonstrating that it’s actually a transition. Contrary to popular belief, if we know how to take care of ourselves during menopause, we can emerge with a renewed, enhanced brain—ushering in a meaningful and vibrant new chapter of life.
11 pages, Audiobook
First published March 21, 2024
1389 people are currently reading
7842 people want to read
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Displaying 1 - 30 of 347 reviews
September 22, 2024
I was quite enthusiastic about this book until I got to Diet and Nutrition section and noticed a lot of “diet culture” verbiage. She spoke of making ‘guilt free’ dark chocolate desserts (when no one should be made to feel guilty for eating certain types of food occasionally).
There were inaccurate recommendations to choose honey and maple syrup over sugar, when there is no scientific advantage to choosing these items - sugar in honey is just sugar, it’s not magically better or more nutritious (trace minerals are so scarce in honey and maple syrup that it’s an extraordinarily weak argument *for* these items being superior).
Finally, she encourages ‘clean’ soy products (there is no scientific definition for ‘clean’, it’s a diet culture term). She demonizes soy in baby formula and more ‘processed’ soy products like soy protein isolates, and also demonizes GMOs. And she encourages organic products.
Ugh. From a scientific nutritional perspective this is wildly misinformed, fearmongering, as well as elitist: organic foods are quite expensive, and there is no evidence that organic products are more beneficial; there is no evidence GMOs are bad for health; and soy protein isolates have actually been shown to reduce cholesterol in post menopausal women.
Who was fact checking Dr. Mosconi’s Diet and Nutrition portion of this book?
There were inaccurate recommendations to choose honey and maple syrup over sugar, when there is no scientific advantage to choosing these items - sugar in honey is just sugar, it’s not magically better or more nutritious (trace minerals are so scarce in honey and maple syrup that it’s an extraordinarily weak argument *for* these items being superior).
Finally, she encourages ‘clean’ soy products (there is no scientific definition for ‘clean’, it’s a diet culture term). She demonizes soy in baby formula and more ‘processed’ soy products like soy protein isolates, and also demonizes GMOs. And she encourages organic products.
Ugh. From a scientific nutritional perspective this is wildly misinformed, fearmongering, as well as elitist: organic foods are quite expensive, and there is no evidence that organic products are more beneficial; there is no evidence GMOs are bad for health; and soy protein isolates have actually been shown to reduce cholesterol in post menopausal women.
Who was fact checking Dr. Mosconi’s Diet and Nutrition portion of this book?
March 27, 2024
I was so excited to read this book and so glad I'm over it. The science and brain/body info is great (stiff shoulders are a menopause complaint are you freaking kidding me?!?). The social aspects of this are a mess.
Would recommend, but with a lot of caveats. Get ready for a lot of moralizing language, diet culture, a weird obsession with being perceived as attractive (yanno, for a science book) and a messy understanding of all things non-binary (sex and gender).
Would recommend, but with a lot of caveats. Get ready for a lot of moralizing language, diet culture, a weird obsession with being perceived as attractive (yanno, for a science book) and a messy understanding of all things non-binary (sex and gender).
May 11, 2024
Let’s call this a “file this information away for future reference” type of read. I got this from the library because it was a new release, and I figured it’d be good to start learning about menopause. I have mixed feelings, but I’m not sure how to untangle them because they are mixed about the book AND about menopause itself. The book was fairly well written, even if she did have some literary quirks that agitated me greatly. (Seriously, stop using ellipsis every time you want to say something remotely funny or quirky or, you know… humorous. Like that, that’s what she did constantly with her ellipsis.) She also waffled between taking a very scientific, professional tone and a touchy-feely, women’s empowerment tone. The last section of the book was dedicated to listing out different treatments and approaches to making menopause more bearable, but by then end I just felt totally defeated. When someone tells you to just “give up using plastic” and “have a positive mindset” and “don’t eat anything processed ever” and “how about you just enjoy a piece of unprocessed cocoa instead,” I feel like I’ll fail before I even get out of bed in the morning.
My feelings on menopause, too, are mixed. The author spent a lot of time trying to tell us it may not be all that bad, but all the evidence pointed to BAD. I kept waiting for the upside she promised, but none really came. She just wants to “change the dialogue” around the inevitable life change, but then she still slips into that old narrative about how we can avoid those few extra pounds heading our way. Ugh.
There were a few shining moments of the book. The section about the three Ps of womanhood — puberty, pregnancy, and perimenopause — explained perimenopause as just another step in the journey, one that may temporarily rock your boat but that you will come out of as a new, probably improved version of yourself. You’ll slough off old, unneeded brain connections that served your younger self and instead focus on what you’re capable of at this stage. What that means for each individual is something only time will tell.
My feelings on menopause, too, are mixed. The author spent a lot of time trying to tell us it may not be all that bad, but all the evidence pointed to BAD. I kept waiting for the upside she promised, but none really came. She just wants to “change the dialogue” around the inevitable life change, but then she still slips into that old narrative about how we can avoid those few extra pounds heading our way. Ugh.
There were a few shining moments of the book. The section about the three Ps of womanhood — puberty, pregnancy, and perimenopause — explained perimenopause as just another step in the journey, one that may temporarily rock your boat but that you will come out of as a new, probably improved version of yourself. You’ll slough off old, unneeded brain connections that served your younger self and instead focus on what you’re capable of at this stage. What that means for each individual is something only time will tell.
March 13, 2024
I was fortunate to have an advance copy of this book. It is a wonderful book, and so vital. If you know anyone who is going through menopause, will someday go through menopause, or has gone through menopause, this book contains important information for them. And although it’s firmly grounded in science, it’s written in plain English. It is also a source of sensible, science-based guidance for anyone who wants to take care of their brain as they age. Want to lower your risk of dementia? Dr. Mosconi has the facts on how important cardiovascular fitness is (and it’s huge: the book cites a long-term study of about 200 midlife women that showed those with the most cardiovascular fitness had 30 percent lower risk of developing dementia than those who were sedentary.) Wondering what the relationship between menopause and the brain is, exactly? You’ve come to the right book. Worried about menopause? This book will explain why you have nothing to fear - while also explaining that your cognitive symptoms are both real and temporary. The book also devotes quite a bit of time to unpacking what your options are for treating bothersome symptoms. There’s even some surprising insight into (yes, really) the upside of menopause (post-menopausal women tend to be happier than younger women and also happier than their own younger selves). Anyway. If you care about your brain - whether menopause is or will be part of your life or not - you should read this book.
September 16, 2024
My abridged version: exercise, eat well, eat less meat and more veg and beans, don’t starve yourself, take your vitamin D, C, iron and omegas, actually limit alcohol, natural soy is yay, sleep, stress-less, your extra belly fat is trying to do you a favour, if you’re approaching late forties you’re likely in the thick of it, HRT as last resort and only for specific symptoms.
April 16, 2024
So far there's some overlap with "The XX Brain" where this book repeats some of the same content. For example- bikini science, how science has ignored females in research studies, no research on female brain, female brain is different than male brain.
Starts out defining the different types of menopause, the stages of menopause and reproduction. Menopause is when you have your last period, and after 1 year with no menstruation you are in post menopause.
Next, it states that the brain changes in menopause and she calls this "menopause brain." There has been evidence of less brain activity compared to the premenopause brain. This could explain "brain fog." I had more brain fog post partum so I'm wondering if pregnancy changes the brain too. And is there a "post partum brain. " Because post partum was more difficult than menopause for me.
I'm most interested in finding out what causes hot flashes (low estrogen? Or the hormone change?), and if hormone replacement therapy is beneficial to prevent Alzheimers and dementia, and any other benefits vs. possible risks. I'm wondering if there will be any mention of what made me sad in menopause- the fact that having the ability to have children is over.
A lot of the same information from both XX Brain and Brain Food especially about foods and diet, exercise, sleep, and water, stress reduction, etc.
Notes on what I found important--->
The brain changes during menopause- developing new neurological and mental skills.
"Menopause is a mind-body experience. "
Sex hormones are involved in brain function.
Ovaries make small amounts of estrogen, testosterone, and androstenedione after menopause.
Symptoms- hot flashes, overactive bladder, joint pain and stiffness, muscle aches, breast soreness irregular heartbeat and palpitations, slower metabolism, bloating, reflux, dry skin, sleep issues, fatigue, dizziness, headaches.
Hot flashes- vasomotor caused by constriction or dilation of blood vessels.
Brain-Ovaries connection-
Hypothalamus: controls body temperature, sleep patterns, appetite.
Pineal gland: secretes hormone melatonin to signal sleep
Thyroid gland: regulates metabolism and temperature.
Pituitary gland- makes hormones
Above glands are involved in the HPG system/connection (Hypothalmic-pituitary-Gonadal) (Ovaries =gonads)
This connection is responsible for menopause symptoms.
The brain is estrogen-fueled, it runs on Estrogen. Estrogen is involved in a number of brain processes. (Pg 67)
Menopause symptoms are the consequences of receptors in the brain getting less of the fuel (estrogen) they need.
3 types of Estrogens-
1. Estradiol- most potent and abundant during reproductive years, produced by ovaries. Reduced levels after menopause.
2. Estrone- made by fatty adipose tissue, weaker effect than Estradiol. Main type of estrogen produced after menopause.
3. Estriol- pregnancy estrogen
Estradiol is the one mainly interacting with the brain, involved in many brain processes- master regulator. See pg. 69 for details.
After menopause, Estrone is now used.
*Since the Hypothalamus controls body temperature, the instability in Estradiol supply means the brain can't regulate body temperature correctly = hot flashes. *
Brain energy changes seem to be temporary, and rebound in energy during late postmenopausal stage, about 4 years after the last period.
Menopause is a neurological transition where the brain adapts and changes to compensate for and maintain brain functions despite the estrogen drop. P74
Supermom brain-
Hormones oxytocin - love and vasopressin- maternal aggression "mama bear" protecting and defending. Mom GPS/tracking. Adrenaline rush. Mom brain leads to theory of mind and motherly instincts.
Menopause shrinks uterine fibroids.
HRT= Hormone replacement therapy-
According to this book, HRT is now safe, as long as started within 10 years of the lmp.
If taken within the 10 year window, hrt is associated with reduced heart disease, lower mortality rate than those who didn't take hormones. (Pg 121) hrt may also protect against cognitive decline. Reduced risk of hip fracture, colorectal cancer, diabetes. (Pg 122) HRT started in midlife may help reduce dementia risk - in the absence of more definitive findings, HRT is not recommended to prevent or treat cognitive decline or dementia. Dr. Mosconi hopes the recommendations will change as more evidence is gathered. (Pg 129)
Ie more research is done!!!
Bioidentical hrt- same as ovary produced estradiol. Micronized progesterone is a molecular replica of progesterone made naturally.
There is little evidence that combination bioidentical estrogen and progesterone increases breast cancer risk.
Government approved and compounded bioidentical hormones- each ingredient is regulated and monitored for purity and efficacy, tested for side effects.
Designer estrogens. SERMS. - a type of hrt to support brain function Hopefully someday this is available.
Dr. Roberta Diaz Brinton, her colleague, developed PhytoSERM, for the brain. Estrogen from plants. Supplies estrogen directly to the brain, bypassing reproductive organs so no cancer risk. They did a clinical trial, results available in 2025. With clinical validation, they hope it will prove valuable to address menopause symptoms and provide extra protection for the brain, protecting against dementia. (Pg 130) I definitely want to watch this!
Non hormonal treatments-
Paroxitine antidepressant for hot flashes.
Gabapentin and clonidine for menopause symptoms.
Fezolinetant for hot flashes.
Chapter 12 Gender-affirming therapy doesn't belong in this book about menopause.
Part 4- lifestyle --- Is the same mostly as her other books Brain Food and XX Brain.
Estrobolome- gut bacteria that metabolize estrogen. Keep things in balance, ensuring that the overall amount of estrogen is just right. (Pg 196). Keep it happy by eating a variety of plant foods, high fiber. Avoid processed foods.
Eat foods with phytoestrogens. 3 types-
1. Isoflavones- soybeans, tofu
2. Lignans- flaxseeds, sesame seeds, garlic, winter squash, wheat grains, pistachios and almonds
3. Coumestans - sprouting seeds
Phytoestrogens function similarly to our estrogen but are weaker- a thousandth of the strength of estradiol. Effects are milder. Only have an effect if consumed consistently.
Increase absorption of plant iron (non-heme iron) by combining with foods rich in Vitamin C. Berries with oats, lemon juice on salad or spinach. Heme iron is in meat and absorbs easily.
Eat organic dairy free of growth hormones.
Pistachios are the most melatonin rich food. Eating a handful is equivalent to taking a melatonin supplement before bed. (Pg 208)
"In the last 70 years, nearly 100k new chemicals have been released into the environment via our food & water supply. At least 85% of these chemicals have never been tested for health effects in humans, so their safety quotient is unknown. Among those that have been tested, as many as 800 chemicals are either known or suspected to negatively impact our health, especially our hormones. " (pg 242)
EDCs= endocrine disrupting chemicals or hormone disrupters. They are chemical contaminants that mimic natural hormones, and prevent cells from communicating. Many mimic estrogen-- xenoestrogens.
These chemicals are toxic to the brain.
Note- I'm going to look up xenoestrogens/ hormone disrupting chemicals. Never heard of this before.
The book ends with this-
"Are you losing your mind during menopause? No, you're getting a brand new one." Pg 264
Starts out defining the different types of menopause, the stages of menopause and reproduction. Menopause is when you have your last period, and after 1 year with no menstruation you are in post menopause.
Next, it states that the brain changes in menopause and she calls this "menopause brain." There has been evidence of less brain activity compared to the premenopause brain. This could explain "brain fog." I had more brain fog post partum so I'm wondering if pregnancy changes the brain too. And is there a "post partum brain. " Because post partum was more difficult than menopause for me.
I'm most interested in finding out what causes hot flashes (low estrogen? Or the hormone change?), and if hormone replacement therapy is beneficial to prevent Alzheimers and dementia, and any other benefits vs. possible risks. I'm wondering if there will be any mention of what made me sad in menopause- the fact that having the ability to have children is over.
A lot of the same information from both XX Brain and Brain Food especially about foods and diet, exercise, sleep, and water, stress reduction, etc.
Notes on what I found important--->
The brain changes during menopause- developing new neurological and mental skills.
"Menopause is a mind-body experience. "
Sex hormones are involved in brain function.
Ovaries make small amounts of estrogen, testosterone, and androstenedione after menopause.
Symptoms- hot flashes, overactive bladder, joint pain and stiffness, muscle aches, breast soreness irregular heartbeat and palpitations, slower metabolism, bloating, reflux, dry skin, sleep issues, fatigue, dizziness, headaches.
Hot flashes- vasomotor caused by constriction or dilation of blood vessels.
Brain-Ovaries connection-
Hypothalamus: controls body temperature, sleep patterns, appetite.
Pineal gland: secretes hormone melatonin to signal sleep
Thyroid gland: regulates metabolism and temperature.
Pituitary gland- makes hormones
Above glands are involved in the HPG system/connection (Hypothalmic-pituitary-Gonadal) (Ovaries =gonads)
This connection is responsible for menopause symptoms.
The brain is estrogen-fueled, it runs on Estrogen. Estrogen is involved in a number of brain processes. (Pg 67)
Menopause symptoms are the consequences of receptors in the brain getting less of the fuel (estrogen) they need.
3 types of Estrogens-
1. Estradiol- most potent and abundant during reproductive years, produced by ovaries. Reduced levels after menopause.
2. Estrone- made by fatty adipose tissue, weaker effect than Estradiol. Main type of estrogen produced after menopause.
3. Estriol- pregnancy estrogen
Estradiol is the one mainly interacting with the brain, involved in many brain processes- master regulator. See pg. 69 for details.
After menopause, Estrone is now used.
*Since the Hypothalamus controls body temperature, the instability in Estradiol supply means the brain can't regulate body temperature correctly = hot flashes. *
Brain energy changes seem to be temporary, and rebound in energy during late postmenopausal stage, about 4 years after the last period.
Menopause is a neurological transition where the brain adapts and changes to compensate for and maintain brain functions despite the estrogen drop. P74
Supermom brain-
Hormones oxytocin - love and vasopressin- maternal aggression "mama bear" protecting and defending. Mom GPS/tracking. Adrenaline rush. Mom brain leads to theory of mind and motherly instincts.
Menopause shrinks uterine fibroids.
HRT= Hormone replacement therapy-
According to this book, HRT is now safe, as long as started within 10 years of the lmp.
If taken within the 10 year window, hrt is associated with reduced heart disease, lower mortality rate than those who didn't take hormones. (Pg 121) hrt may also protect against cognitive decline. Reduced risk of hip fracture, colorectal cancer, diabetes. (Pg 122) HRT started in midlife may help reduce dementia risk - in the absence of more definitive findings, HRT is not recommended to prevent or treat cognitive decline or dementia. Dr. Mosconi hopes the recommendations will change as more evidence is gathered. (Pg 129)
Ie more research is done!!!
Bioidentical hrt- same as ovary produced estradiol. Micronized progesterone is a molecular replica of progesterone made naturally.
There is little evidence that combination bioidentical estrogen and progesterone increases breast cancer risk.
Government approved and compounded bioidentical hormones- each ingredient is regulated and monitored for purity and efficacy, tested for side effects.
Designer estrogens. SERMS. - a type of hrt to support brain function Hopefully someday this is available.
Dr. Roberta Diaz Brinton, her colleague, developed PhytoSERM, for the brain. Estrogen from plants. Supplies estrogen directly to the brain, bypassing reproductive organs so no cancer risk. They did a clinical trial, results available in 2025. With clinical validation, they hope it will prove valuable to address menopause symptoms and provide extra protection for the brain, protecting against dementia. (Pg 130) I definitely want to watch this!
Non hormonal treatments-
Paroxitine antidepressant for hot flashes.
Gabapentin and clonidine for menopause symptoms.
Fezolinetant for hot flashes.
Chapter 12 Gender-affirming therapy doesn't belong in this book about menopause.
Part 4- lifestyle --- Is the same mostly as her other books Brain Food and XX Brain.
Estrobolome- gut bacteria that metabolize estrogen. Keep things in balance, ensuring that the overall amount of estrogen is just right. (Pg 196). Keep it happy by eating a variety of plant foods, high fiber. Avoid processed foods.
Eat foods with phytoestrogens. 3 types-
1. Isoflavones- soybeans, tofu
2. Lignans- flaxseeds, sesame seeds, garlic, winter squash, wheat grains, pistachios and almonds
3. Coumestans - sprouting seeds
Phytoestrogens function similarly to our estrogen but are weaker- a thousandth of the strength of estradiol. Effects are milder. Only have an effect if consumed consistently.
Increase absorption of plant iron (non-heme iron) by combining with foods rich in Vitamin C. Berries with oats, lemon juice on salad or spinach. Heme iron is in meat and absorbs easily.
Eat organic dairy free of growth hormones.
Pistachios are the most melatonin rich food. Eating a handful is equivalent to taking a melatonin supplement before bed. (Pg 208)
"In the last 70 years, nearly 100k new chemicals have been released into the environment via our food & water supply. At least 85% of these chemicals have never been tested for health effects in humans, so their safety quotient is unknown. Among those that have been tested, as many as 800 chemicals are either known or suspected to negatively impact our health, especially our hormones. " (pg 242)
EDCs= endocrine disrupting chemicals or hormone disrupters. They are chemical contaminants that mimic natural hormones, and prevent cells from communicating. Many mimic estrogen-- xenoestrogens.
These chemicals are toxic to the brain.
Note- I'm going to look up xenoestrogens/ hormone disrupting chemicals. Never heard of this before.
The book ends with this-
"Are you losing your mind during menopause? No, you're getting a brand new one." Pg 264
This entire review has been hidden because of spoilers.
June 29, 2025
Every woman should read this book - and not when she's perimenopausal or post-menopausal. I feel like if I'd been armed with all this great information, I might've been readier for the hot flashes once they came! I really should've started reading these kind of books much sooner (like, this one and Dr. Marie Claire Haver's The New Menopause and Dr. Karen Tang's It's Not Hysteria, for example). I would actually encourage women to start reading these books far before perimenopause, especially Dr. Tang's book since it covers a heck of a lot more than just menopause.
I had read another book by Dr. Mosconi called Brain Food. I loved that one too. What I like about her books is that she is a Cornell University researcher and teacher, as well as a bonafide neurologist, with a sub specialty in neuronutrition! To me, she is a super rock star. She is the god of all rock stars, in fact. I want to download all that is in her brain into mine. I find the information consumable, memorable, desirable. I want to reread these books over and over again until I've memorized every word, and if my library queue wasn't so long, maybe I'd try.
My only issue with any of these kind of self-help books is that it's impossible for me to follow every suggestion. Impractical. But I can, and I try, to do as many of the recommendations in principle only. I can truly say that my health and life have steadily trended upward as I started adding in one new learned lesson after another. I take my time and wait until I'm comfortable with where I get to before I get to the next one. Works for me. Hope these books work for many others as well.
I had read another book by Dr. Mosconi called Brain Food. I loved that one too. What I like about her books is that she is a Cornell University researcher and teacher, as well as a bonafide neurologist, with a sub specialty in neuronutrition! To me, she is a super rock star. She is the god of all rock stars, in fact. I want to download all that is in her brain into mine. I find the information consumable, memorable, desirable. I want to reread these books over and over again until I've memorized every word, and if my library queue wasn't so long, maybe I'd try.
My only issue with any of these kind of self-help books is that it's impossible for me to follow every suggestion. Impractical. But I can, and I try, to do as many of the recommendations in principle only. I can truly say that my health and life have steadily trended upward as I started adding in one new learned lesson after another. I take my time and wait until I'm comfortable with where I get to before I get to the next one. Works for me. Hope these books work for many others as well.
July 16, 2024
The first half of the book was full of interesting information about the effect of hormones on the brain; helpful, informative, I started recommending it to friends.
But then the author dove deep into diet culture tropes and, while I am 100% thrilled to advocate for less processed food and minimizing plastic use, the vehemence and unattainable recommendations to remove all processed foods and plastics from one's life was more than a bit over the top. I felt like the author lost the thread of her own book.
SO, read the first half and just be done before you get to the suggestions. It's nothing that hasn't been said a million times by the supplement-hocking menopause celebrities and it felt completely out of touch with reality.
But then the author dove deep into diet culture tropes and, while I am 100% thrilled to advocate for less processed food and minimizing plastic use, the vehemence and unattainable recommendations to remove all processed foods and plastics from one's life was more than a bit over the top. I felt like the author lost the thread of her own book.
SO, read the first half and just be done before you get to the suggestions. It's nothing that hasn't been said a million times by the supplement-hocking menopause celebrities and it felt completely out of touch with reality.
June 27, 2024
I have very mixed feelings about this book. It had some decent information but the delivery didn’t work for me.
I set a goal to read 20 pages a day to educate myself about menopause, my second read on the topic, and it was a struggle.
Part textbook/ part “woke” view of menopause, complete with explanations of gender identity - about MENOPAUSE- Ridiculous. 😒 😡
So it irked me from the get-go, but I pushed through it, if for no other reason than to understand the basics of hormones and HRT. I learned about the history of menopausal treatment, trials, and lack of education in the medical community.
It’s very disconcerting to know that doctors, and patients by default, are so under educated and/or miseducated about menopause & the terrible old studies about HRT. This leads many to discourage women from hormone replacement therapy.
It seems this author started with the strong premise of explaining the neuroscience perspective, but wandered off into various directions. These included various examples ranging from
1)fear-mongering (Toxins! Everywhere! No matter what you do you’re gonna die) Chapter 17
2)toxic-positivity (ironically immediately following that) Chapter 18. This also included the chapters on diet, exercise, sleep, the upside of menopause, and the power of positivity.
OMG it’s like TOTALLY guaranteed to “fix” anyone dealing with mental illness either pre-existing or due to menopause.🙄
Seriously though, not a single nod was made to any woman who has dealt with trauma or depression and is now worse off in menopause. And that is science backed information that would have fit.
3) virtue-signaling using buzz words like misogyny and a whole chapter on gender-affirming care.
I felt like I was being lectured by a know-it-all, size zero celebrity, who doesn’t seem to understand what it’s like to suffer through menopause. The chapters about diet and exercise are quite often overwhelming for most women. Again, these things aren’t always possible with underlying illness, medications, etc. and lack of energy and motivation are huge obstacles for many menopausal women.
The supplements chapter was particularly unhelpful as most of the ones mentioned were listed as having low efficacy and side effects. Why bother including those?
I found that the later chapters I just wasn’t learning anything new. Mindfulness is old news. Utilize a support system- sure. Cause everyone has one. 😒 Try yoga. Sleep better. Etc. Nothing novel especially if you have read any self-help book, online post or article in a magazine prior to this book.
So it wasn’t the right book for me but maybe you’ll enjoy it. I just found myself with a lot of menopausal rage and dissatisfaction because I don’t have round the clock nutritionists, chefs, personal trainers, physical therapists and and more than 2% energy level on any given day.
3 stars because I did still learn something.
I set a goal to read 20 pages a day to educate myself about menopause, my second read on the topic, and it was a struggle.
Part textbook/ part “woke” view of menopause, complete with explanations of gender identity - about MENOPAUSE- Ridiculous. 😒 😡
So it irked me from the get-go, but I pushed through it, if for no other reason than to understand the basics of hormones and HRT. I learned about the history of menopausal treatment, trials, and lack of education in the medical community.
It’s very disconcerting to know that doctors, and patients by default, are so under educated and/or miseducated about menopause & the terrible old studies about HRT. This leads many to discourage women from hormone replacement therapy.
It seems this author started with the strong premise of explaining the neuroscience perspective, but wandered off into various directions. These included various examples ranging from
1)fear-mongering (Toxins! Everywhere! No matter what you do you’re gonna die) Chapter 17
2)toxic-positivity (ironically immediately following that) Chapter 18. This also included the chapters on diet, exercise, sleep, the upside of menopause, and the power of positivity.
OMG it’s like TOTALLY guaranteed to “fix” anyone dealing with mental illness either pre-existing or due to menopause.🙄
Seriously though, not a single nod was made to any woman who has dealt with trauma or depression and is now worse off in menopause. And that is science backed information that would have fit.
3) virtue-signaling using buzz words like misogyny and a whole chapter on gender-affirming care.
I felt like I was being lectured by a know-it-all, size zero celebrity, who doesn’t seem to understand what it’s like to suffer through menopause. The chapters about diet and exercise are quite often overwhelming for most women. Again, these things aren’t always possible with underlying illness, medications, etc. and lack of energy and motivation are huge obstacles for many menopausal women.
The supplements chapter was particularly unhelpful as most of the ones mentioned were listed as having low efficacy and side effects. Why bother including those?
I found that the later chapters I just wasn’t learning anything new. Mindfulness is old news. Utilize a support system- sure. Cause everyone has one. 😒 Try yoga. Sleep better. Etc. Nothing novel especially if you have read any self-help book, online post or article in a magazine prior to this book.
So it wasn’t the right book for me but maybe you’ll enjoy it. I just found myself with a lot of menopausal rage and dissatisfaction because I don’t have round the clock nutritionists, chefs, personal trainers, physical therapists and and more than 2% energy level on any given day.
3 stars because I did still learn something.
October 4, 2025
The best thing I took away from this book was simply knowing that science shows perimenopause brain fog is not a permanent change of your intellecutal and congitive abilities. Whew. The rest of the material in this book is a mixed bag, as it requires you to wade through some diet culture lingo and a focus on physical appearance.
November 11, 2025
2.5ish
I have read two to other great books on this subject and was really looking forward to this one that specializes on the brain.
I cannot fully recommend it as it goes against my Christian worldviews and really didn't have that much on the brain. It was heavy on evolution, completely missing the mark how beautiful our bodies are and the natural progression of ageing that our Creator intended for.
I skipped a whole chapter as it dealt with transgenderism and how men who used to be women now deal with periods. I can't evend understand how we try to rationalize this. I felt like a definite political agenda was in play.
Suffice it to say the little bit of research and studies showing a correlation of lessening hormones and ovary production to the grey matter in the brain was fascinating. And of course there is a correlation.
𝘔𝘰𝘳𝘦 𝘵𝘩𝘰𝘶𝘨𝘩𝘵𝘴 𝘢𝘯𝘥 𝘳𝘦𝘷𝘪𝘦𝘸𝘴 𝘤𝘢𝘯 𝘣𝘦 𝘧𝘰𝘶𝘯𝘥 𝘢𝘵:𝘩𝘵𝘵𝘱𝘴://𝘸𝘸𝘸.𝘪𝘯𝘴𝘵𝘢𝘨𝘳𝘢𝘮.𝘤𝘰𝘮/𝘮𝘰𝘵𝘩𝘦𝘳𝘭𝘢𝘮𝘣𝘳𝘦𝘢𝘥𝘴/
I have read two to other great books on this subject and was really looking forward to this one that specializes on the brain.
I cannot fully recommend it as it goes against my Christian worldviews and really didn't have that much on the brain. It was heavy on evolution, completely missing the mark how beautiful our bodies are and the natural progression of ageing that our Creator intended for.
I skipped a whole chapter as it dealt with transgenderism and how men who used to be women now deal with periods. I can't evend understand how we try to rationalize this. I felt like a definite political agenda was in play.
Suffice it to say the little bit of research and studies showing a correlation of lessening hormones and ovary production to the grey matter in the brain was fascinating. And of course there is a correlation.
𝘔𝘰𝘳𝘦 𝘵𝘩𝘰𝘶𝘨𝘩𝘵𝘴 𝘢𝘯𝘥 𝘳𝘦𝘷𝘪𝘦𝘸𝘴 𝘤𝘢𝘯 𝘣𝘦 𝘧𝘰𝘶𝘯𝘥 𝘢𝘵:𝘩𝘵𝘵𝘱𝘴://𝘸𝘸𝘸.𝘪𝘯𝘴𝘵𝘢𝘨𝘳𝘢𝘮.𝘤𝘰𝘮/𝘮𝘰𝘵𝘩𝘦𝘳𝘭𝘢𝘮𝘣𝘳𝘦𝘢𝘥𝘴/
November 17, 2024
First, I'm not a bot -- some of the reviews look like they are generated by bots (they all start off with similar sentences).
I listened to this as an audio book and really appreciated the first part of the book which discusses the strengths and weaknesses of studies (or lack thereof) related to women's health. The bottom line is that estrogen (and progesterone) are prophylactic for so many health conditions. The author also talks about how perimenopause is not given the same respect or support as puberty and pregnancy. When I started perimenopause, it was like being hit by a pile of bricks. I was running, swimming, climbing and bicycling -- and suddenly -- I was falling asleep at my desk at work, impacted by brain fog. I took a 5 week sick leave and when I returned, my (younger) manager tsk tsked me and repeatedly expressed her disapproval (ie, "Five weeks is a REALLY LONG TIME). Never mind the fact that I had been at the organization 5 years and most FTEs would have already been taking a sabbatical -- I was put on a "performance improvement plan." Upon completion, I was informed that they were doing another 3 month PIP to give me even more opportunity to improve (and not getting my annual bonus or merit increase).
I really felt like I was losing my mind -- and even going to doctors was futile: "Just embrace it," and "How old are you? Oh, just tough it out, you're almost there." My PCP even sent me numerous depression quizzes and wouldn't listen to me when I told her that I was, indeed, cutting back on alcohol and sugar, following recommended sleep hygiene improvements, and so on.
It wasn't until TWO years ago (a few months after my last menstrual period) when a transwoman suggested I find an endocrinologist who worked with trans folk that I finally got a plan that has eliminated the hot flushes, reduced the cognitive fog, improved a lot of other things.
Unless you're subsisting on the Standard American Diet of processed food and simple carbs, the diet and lifestyle section at the end isn't going to look strange. The author refers people to the Environmental Working Group (EWG) database to educate themselves about which foods to avoid as conventionally grown (ie, celery which isn't really food anyway) and which are ok to buy as conventional (vs organic) like avocados. She's not saying "buy everything organic and go vegan" -- some people are missing the message: women's bodies change in menopause and you need the nutrients in leafy greens and it's about quality of nutrition. It's a difficult concept for some people to grasp.
My favorite takeaway: I learned that pistachios have a lot of melatonin - and a serving before bed can help with sleep (I usually have some shelled pistachios with dried cherries as my evening snack).
Reading through the reviews, I find it interesting how people react to the content of the book and seem to be intimidated by someone who would dare discuss topics outside the cis-woman experience, or recommend eating a more plant based diet based on research as a good idea. While the author may veer off into a bit of "woo" (ie, aromatherapy) she is really clear about "do what you can, eat the best that you can, and if something helps reduce stress - try it." It's frankly shocking how many reviewers push back against things like meditation and chanting as "woke" -- they probably don't realize how deeply programmed they are by the cultural pressure to be "productive" and what kind of toll it is taking on them.
Overall - it's a good book and if this is the first or only book you read about menopause, you'd be covering most contemporary research.
Even if you are a die hard fantasist who doesn't believe in evolution and might be called a TERF -- you should read this book because the symptoms and experiences can vary across the board. You can arm yourself with information and put together a plan to reclaim your life as you transition out of fertility.
I listened to this as an audio book and really appreciated the first part of the book which discusses the strengths and weaknesses of studies (or lack thereof) related to women's health. The bottom line is that estrogen (and progesterone) are prophylactic for so many health conditions. The author also talks about how perimenopause is not given the same respect or support as puberty and pregnancy. When I started perimenopause, it was like being hit by a pile of bricks. I was running, swimming, climbing and bicycling -- and suddenly -- I was falling asleep at my desk at work, impacted by brain fog. I took a 5 week sick leave and when I returned, my (younger) manager tsk tsked me and repeatedly expressed her disapproval (ie, "Five weeks is a REALLY LONG TIME). Never mind the fact that I had been at the organization 5 years and most FTEs would have already been taking a sabbatical -- I was put on a "performance improvement plan." Upon completion, I was informed that they were doing another 3 month PIP to give me even more opportunity to improve (and not getting my annual bonus or merit increase).
I really felt like I was losing my mind -- and even going to doctors was futile: "Just embrace it," and "How old are you? Oh, just tough it out, you're almost there." My PCP even sent me numerous depression quizzes and wouldn't listen to me when I told her that I was, indeed, cutting back on alcohol and sugar, following recommended sleep hygiene improvements, and so on.
It wasn't until TWO years ago (a few months after my last menstrual period) when a transwoman suggested I find an endocrinologist who worked with trans folk that I finally got a plan that has eliminated the hot flushes, reduced the cognitive fog, improved a lot of other things.
Unless you're subsisting on the Standard American Diet of processed food and simple carbs, the diet and lifestyle section at the end isn't going to look strange. The author refers people to the Environmental Working Group (EWG) database to educate themselves about which foods to avoid as conventionally grown (ie, celery which isn't really food anyway) and which are ok to buy as conventional (vs organic) like avocados. She's not saying "buy everything organic and go vegan" -- some people are missing the message: women's bodies change in menopause and you need the nutrients in leafy greens and it's about quality of nutrition. It's a difficult concept for some people to grasp.
My favorite takeaway: I learned that pistachios have a lot of melatonin - and a serving before bed can help with sleep (I usually have some shelled pistachios with dried cherries as my evening snack).
Reading through the reviews, I find it interesting how people react to the content of the book and seem to be intimidated by someone who would dare discuss topics outside the cis-woman experience, or recommend eating a more plant based diet based on research as a good idea. While the author may veer off into a bit of "woo" (ie, aromatherapy) she is really clear about "do what you can, eat the best that you can, and if something helps reduce stress - try it." It's frankly shocking how many reviewers push back against things like meditation and chanting as "woke" -- they probably don't realize how deeply programmed they are by the cultural pressure to be "productive" and what kind of toll it is taking on them.
Overall - it's a good book and if this is the first or only book you read about menopause, you'd be covering most contemporary research.
Even if you are a die hard fantasist who doesn't believe in evolution and might be called a TERF -- you should read this book because the symptoms and experiences can vary across the board. You can arm yourself with information and put together a plan to reclaim your life as you transition out of fertility.
May 19, 2025
my expectations were high because i listened to the author on a podcast and she was fantastic. the second half of the book felt kind of repetitive and superficial and just a regurgitation of the classic eat and exercise and all will be well. i rlly thought she was gonna make the actual science of the menopausal brain more accessible since it’s written for a general audience but i was disappointed cuz it was just a pretty simplistic explanation of things. however, i did learn some things that blew my mind (no one’s studied women ever ill never get over how bad the hormone replacement study that that we still cite to this day was!!) so that was a positive takeaway. overall i have decided to both fear and be excited for menopause. women are at their happiest after menopause guys so it’s not all bad!!
May 7, 2024
First half was super interesting and even reassuring. Second half was about following a certain diet and I’m committed to intuitive eating and not dieting, so didn’t find this helpful.I did like the book, but didn’t feel there was anything life altering…and she focused almost entirely on estrogen (which makes me feel amazing) but said almost nothing about progesterone.
March 11, 2024
This is a fantastic book ! With so many things I can relate to and learn from! The author writes in a way I can understand . It definitely deserves five stars!
October 26, 2025
Me parece un libro magnífico sobre el tema de la menopausia. Inclusivo, empático, son muchísimos estudios recientes y, sobre todo, respetuoso y —por qué no— positivo.
Es lamentable que algo que vivimos el 50% de la población sea un tema tan poco tratado, por no hablar del estigma de la mujer menopáusica. Es terrible todo lo que hemos tenido que aguantar en las décadas anteriores y cómo llegamos a vernos a nosotras mismas como alguien “caducado”.
Todas las mujeres deberían leer este libro. Y hombres también, pero no tengo mucha esperanza depositada en ello.
Es lamentable que algo que vivimos el 50% de la población sea un tema tan poco tratado, por no hablar del estigma de la mujer menopáusica. Es terrible todo lo que hemos tenido que aguantar en las décadas anteriores y cómo llegamos a vernos a nosotras mismas como alguien “caducado”.
Todas las mujeres deberían leer este libro. Y hombres también, pero no tengo mucha esperanza depositada en ello.
January 16, 2025
I wasn’t going to log this book in Goodreads, as it would confirm my outing as a “woman of a certain age.” And that’s exactly the problem: Not only do we not know enough about major brain/body changes that happen in every single woman who reaches that “certain age”… but our society treats this natural and guaranteed journey like a disease. It’s not. This book helped me cast it in a new light, as something to celebrate, something amazing - even if still largely mysterious - that happens to any and every woman who lives long enough. Combine it with the life experience, wisdom, and body knowledge you’ve built up since birth and the menopausal journey should be celebrated just as we celebrate births and adulthood.
This book taught (or reminded) me that certain cultures view this period as a positive. In some communities, post menopausal women gain status, can shed strict gender roles, or liken the experience to freedom. Thank the goddess! 😉 I, on the other hand, feel like I shouldn’t mention my age at work or sometimes amongst friends for fear that I will be minimized or treated as less relevant. This is not just my hang up. We largely discount our older women and we certainly treat the menopause experience in my culture as a joke, a weakness, something to “get over.” I now call bullshit on that. Maybe if I start talking about it more (as many brave women before me have done), I can help contribute to a refreshed cultural view of menopause.
To be fair, my new view on this doesn’t come from just this book. The Menopause Brain is largely about the science around the brain and body changes that occur and ways we can support those changes. It’s written well, easily understandable, and compelling. It was recommended to me by the instructors at a retreat on menopause. I’ve personally been building toward this moment and realization. If you want to know more about what happens to women’s brains and bodies during their extraordinary life journey, then this is a great book with which to start.
This book taught (or reminded) me that certain cultures view this period as a positive. In some communities, post menopausal women gain status, can shed strict gender roles, or liken the experience to freedom. Thank the goddess! 😉 I, on the other hand, feel like I shouldn’t mention my age at work or sometimes amongst friends for fear that I will be minimized or treated as less relevant. This is not just my hang up. We largely discount our older women and we certainly treat the menopause experience in my culture as a joke, a weakness, something to “get over.” I now call bullshit on that. Maybe if I start talking about it more (as many brave women before me have done), I can help contribute to a refreshed cultural view of menopause.
To be fair, my new view on this doesn’t come from just this book. The Menopause Brain is largely about the science around the brain and body changes that occur and ways we can support those changes. It’s written well, easily understandable, and compelling. It was recommended to me by the instructors at a retreat on menopause. I’ve personally been building toward this moment and realization. If you want to know more about what happens to women’s brains and bodies during their extraordinary life journey, then this is a great book with which to start.
February 4, 2025
I agree with many of the other reviews. I found the first half of the book helpful and digestible. I also appreciated the information on nutrition and behavioral resources.
My main qualm is that most people know to eat well, exercise, reduce stress etc. yes, those are powerful tools, but if we do not address the barriers that prevent people from using those tools, we are just telling people that they’re not doing enough which can feel like telling someone that their symptoms are their fault leading to feelings of powerlessness.
Yes, the author notes financial barriers to wellness practices, but our systems are not set up to support folks who are already struggling to get by or those who may doing the most they can already. People do not have the bandwidth to make healthy choices when they are barely getting by.
The solution? Huge systemic changes. Relational support. Some might say “a village” or people caring for one another throughout life.
My main qualm is that most people know to eat well, exercise, reduce stress etc. yes, those are powerful tools, but if we do not address the barriers that prevent people from using those tools, we are just telling people that they’re not doing enough which can feel like telling someone that their symptoms are their fault leading to feelings of powerlessness.
Yes, the author notes financial barriers to wellness practices, but our systems are not set up to support folks who are already struggling to get by or those who may doing the most they can already. People do not have the bandwidth to make healthy choices when they are barely getting by.
The solution? Huge systemic changes. Relational support. Some might say “a village” or people caring for one another throughout life.
July 18, 2024
Mixed feelings on this one. I’m glad I read it; there’s good information, especially early on. But the delivery didn’t work for me. I was annoyed by the excessive exclamation points and use of italics. I also found the chapters about positive mindset and avoiding toxins/sugar/processed foods particularly unhelpful. And it’s hard to take her seriously when she says chewing unprocessed cocoa is a “guilt-free treat” or, if pressed for time, to just plank for 10 minutes. I wish I’d stopped reading after the chapter on HRT, or just stick with her TED Talk.
August 1, 2024
Easy to understand, informative read. I skipped the chapter on Gender-Affirming Therapy. Unlike others that have made complaint I found the diet and nutrition chapters on-point, offering great information; the same advice Peter Attia provides in his book, Outlive.
“Nobody puts a perennial in the corner.” (p263) - LOVE IT!
“Nobody puts a perennial in the corner.” (p263) - LOVE IT!
October 7, 2024
This book is excellent and fascinating. I was particularly impressed with the new science of how the brain responds to hormonal changes. I feel both empowered and obsessed.
That said, I’m confused and disheartened by the way doctors and scientists (including this author) think we should definitely try to get on HRT. Idk. I just don’t want to need meds to cope with changes that will usher me into the next, best stage of my life. She does offer other options and advice.
That said, I’m confused and disheartened by the way doctors and scientists (including this author) think we should definitely try to get on HRT. Idk. I just don’t want to need meds to cope with changes that will usher me into the next, best stage of my life. She does offer other options and advice.
December 7, 2024
4.5⭐️ this was informative and a good one to read after the teachings from Dr. Mary Haver’s book the new menopause.
June 30, 2025
I skimmed this one; stopping to read sections of relevance. I learned some new things and appreciated the balance of science explanations and straight talk.
April 7, 2024
Libby audio. A little dry in parts. A little repetitive in parts - but I think that is meant for people that are skipping around to sections.
June 14, 2024
The author delves into the fascinating ways hormonal changes influence both the body and mental health. The book dispels common misconceptions about hormonal balance and control, offering insights into how diet, exercise, skincare, and complementary vitamins can support well-being during this transition. It also explores the diverse perceptions of menopause across different cultures, highlighting how it is viewed as a time of revival in Far Eastern regions, holds significant meaning for Native Americans, and is celebrated in various other communities.
July 16, 2025
A valuable resource for figuring what the heck a body and mind are doing.
December 25, 2024
I think I will give this book as a gift to every woman I know on her 40th birthday. We really should know the science behind the next chapter of our lives BEFORE we start feeling the biological changes. In a way, my mother’s generation normalized preparing girls for their first period. I hope my generation normalizes preparing our daughters for menopause.
September 24, 2025
Leading neuroscientist and women’s brain health specialist, Dr. Lisa Mosconi explains the do's and don'ts of menopause.
This was an interesting book about menopause. Dr. Mosconi's take on it was humorous, candid and most of all, positive, and I would recommend it to all women.
Here is a quick recap of what she recommended: Moderate daily exercise. Resistance training. A plant-based, Mediterranean, high fiber diet is best. EAT fish, peas, beans, lima beans, chickpeas, avocado, green tea, blueberries, tomatoes, goji, grapes, artichoke, blackberries, Brazil nuts, citrus fruit, beets, kale, spinach, cabbage, romaine, cauliflower, broccoli, brussel sprouts, asparagus, sweet/baked potatoes, tofu, sauerkraut, flax, sesame, dried apricots and peaches. ENJOY 80% chocolate and spices such as cinnamon, oregano, rosemary, and garlic. AVOID alcohol, white rice, pasta, red meat, and processed foods.
Audiobook
This was an interesting book about menopause. Dr. Mosconi's take on it was humorous, candid and most of all, positive, and I would recommend it to all women.
Here is a quick recap of what she recommended: Moderate daily exercise. Resistance training. A plant-based, Mediterranean, high fiber diet is best. EAT fish, peas, beans, lima beans, chickpeas, avocado, green tea, blueberries, tomatoes, goji, grapes, artichoke, blackberries, Brazil nuts, citrus fruit, beets, kale, spinach, cabbage, romaine, cauliflower, broccoli, brussel sprouts, asparagus, sweet/baked potatoes, tofu, sauerkraut, flax, sesame, dried apricots and peaches. ENJOY 80% chocolate and spices such as cinnamon, oregano, rosemary, and garlic. AVOID alcohol, white rice, pasta, red meat, and processed foods.
Audiobook
July 1, 2024
Very fast paced and interesting reading, digs into some feminist issues along the way to give perspective on women's health. I really feel like women should be reading about every stage of their bodies and brains way before it seems relevant. We're very ill prepared for the changes we experience and it would help to destigmatize a crucial season in every woman's life.
October 27, 2024
this book has some good information but it was not as advertised. I have a lot of menopause knowledge and have read several books by other experts such as Dr Jen Gunter and Dr Mary Claire Haver, so I didn’t need another menopause primer. I was excited to hear about menopause and the brain and dementia which hadn’t been covered in those other books. Unfortunately, this section is quite small. Maybe because this research is developing and there isn’t that much to say. To fill out the rest of the book she gave basic details which were not a well covered as in other books.
She also slips in biases towards a plant based diet, which I’m not opposed to but not what I needed. As well as a little fear mongering about what is in our food. As a child of diet culture, I’m trying hard to eliminate this from my life. The rules are too numerous, overwhelming and conflicting. I’m not looking to add more now.
You’re better served by skipping this one and reading a book by one of the authors mention above
She also slips in biases towards a plant based diet, which I’m not opposed to but not what I needed. As well as a little fear mongering about what is in our food. As a child of diet culture, I’m trying hard to eliminate this from my life. The rules are too numerous, overwhelming and conflicting. I’m not looking to add more now.
You’re better served by skipping this one and reading a book by one of the authors mention above
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