Subcellular Biochemistry, Volume 60: Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease

by Tony Harris (Editor)

Cell–cell adhesion is fundamental for the development and homeostasis of animal tissues and organs. Adherens junctions (AJs) are the best understood cell-cell adhesion complexes. In this volume, a group of internationally recognized experts reviews AJ biology over a wide range of organization; from atoms to molecules, to protein complexes, molecular networks, cells, tissues, and overall animal development. AJs have also been an integral part of animal evolution, and play central roles in cancer development, pathogen infection and other diseases. This book addresses major questions encompassing AJ biology.
• How did AJs evolve?
• How do cadherins and catenins interact to assemble AJs and mediate adhesion?
• How do AJs interface with other cellular machinery to couple adhesion with the whole cell?
• How do AJs affect cell behaviour and multicellular development?
• How can abnormal AJ activity lead to disease?

440 pages, Paperback

First published January 1, 2012

About the author

Tony Harris (born 1969) is an American comic book artist, known for his work on series such as Starman, Iron Man, and Ex Machina. He has been nominated for five Eisner Awards.


Librarian Note: There is more than one author in the Goodreads' database with this name. See this thread for more information.