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288 pages, Hardcover
Published September 30, 2025
Tetraethyl lead (TEL) was marketed as a miracle product. The dangers of working with lead compounds were already well known, but even the deaths of five workers in a factory making TEL did little to impede its popularity. The New York Times noted the controversy over TEL at the time, but in an editorial of 28 November 1924 concluded that the recent deaths were 'not a sufficient reason for abandoning the use of a substance by means of which a large economic gain could be effected - that is, a considerable increase in the value of gasoline as a source of power.' The world seemed to agree that TEL was worth the risk, and the motor car took over the Earth.
It is impossible to say exactly how many millions of tonnes of lead were pumped into the atmosphere and environment by Midgley's creation of leaded fuel, nor can the effect on human health be fully known. By some estimates, perhaps 100 million deaths occurred prematurely due to increased levels of lead building up in human bodies. Millions may still be dying early each year, even though leaded fuels have mostly been phased out, due to residual lead in the environment.
Midgley was not content to rest on his laurels after his leaded fuel breakthrough. He knew that for refrigeration and air conditioning to become widely used, a new chemical refrigerant would need to be invented that did not carry the same risks of combustion as those used at the time. With little more than a pocket periodic table and a hunch, he concluded that any such compound would have to be built around fluorine, a ferociously reactive element. Midgley and his team soon created Freon, a form of chlorofluorocarbon. Chlorofluorocarbons would become known to generations as the dreaded CFC chemicals responsible for the destruction of the ozone layer.
CFCs are non-toxic when inhaled by mammals, so Midgley concluded that they were safe. The problem comes when they drift into the upper atmosphere, because CFCs catalyze a reaction that tears apart the ozone molecules that block many of the sun's harmful UV rays. Without the ozone layer, dangerous amounts of UV reach the Earth's surface and can cause skin cancers and cataracts. As an additional bonus, CFCs also contribute directly to global warming.