Change Your Brain, Change Your Pain: Breaking the Doom Loop to Heal Chronic Physical and Emotional Pain

by Daniel G. Amen

One of our leading experts on the brain and #1 New York Times bestselling author explores how chronic physical and emotional pain are both rooted in your brain’s wiring, leaving you stuck in the doom loop and how you can break free to heal them free from the 'doom loop' and reclaim a vibrant, pain-free life.

In the United States alone, one in five adults experiences chronic pain. For too long, when a doctor couldn’t find the source of frequent pain, the patient was dismissively told “it’s all in your head.” Today, we know that our somatic responses to trauma, anxiety, and depression create real suffering, and that physical pain can lead to trauma, anxiety, and depression. Dr. Daniel Amen calls this “the doom loop”—the dance between physical and emotional pain. These doom loops interfere with our ability to live our lives. But we can shift the doom loop into a healing loop, and in this vital book, he shows us how.

Dr. Amen has been researching a new brain-based approach to pain. In Change Your Brain, Change Your Pain he draws on those studies to

Pain producing versus pain soothing thought patterns Muscle tension and trauma vs calmness and clarity The use of medical and nutraceuticals to help calm the pathways The effects of diet, exercise, meditation, breath to help pain Our current approach to understanding and treating physical and emotional pain is misguided. Change Your Brain, Change Your Pain offers a healthier way, one that involves less medication, less surgery, and better outcomes. Just like the human heart, the human brain is an organ, and that to be free of emotional or physical pain, it is critical to get the brain as healthy as it can be—not just physically, but emotionally, psychologically, and spiritually, as well.

Genres: Nonfiction, Psychology, Health

480 pages, Hardcover

Published December 2, 2025

About the author

The Washington Post called Dr. Daniel Amen the most popular psychiatrist in America and Sharecare.com named him the web's most influential expert and advocate on mental health.
Daniel Amen is a life-long Christian and graduate of Oral Roberts University School of Medicine. He is a double board-certified psychiatrist and multiple NY Times bestselling author, with such blockbuster books as Change Your Brain, Change Your Life, Healing ADD, Change Your Brain, Change Your Body, and The Daniel Plan, co-authored by Pastor Rick Warren and Dr. Mark Hyman. In November 2016, he and his wife Tana published The Brain Warrior's Way.
Dr. Amen is the founder of Amen Clinics, which has 6 locations across the United States. Amen Clinics has the world's largest database of brain scans related to behavior, totaling more than 125,000 SPECT scans on patients from 111 countries.
Dr. Amen's research team has published more than 70 scientific articles on a wide variety of topics related to brain health. He is the lead researcher on the largest brain imaging study on active and retired NFL players and was a consultant on the movie Concussion starring Will Smith. In 2016, Discover Magazine named his brain imaging work for psychiatric diagnoses as one of the top 100 stories in all of science.
Dr. Amen has also hosted 11 national public television shows about the brain, which have aired more than 80,000 times across North America and raised more than 75 million dollars for stations.

You can connect with Dr. Amen on Facebook and Twitter

Reviews

[Sarah Tsibulsky · Rating 4 out of 5]

Some good strategies for reducing pain.

[Zhuo Zhang · Rating 2 out of 5]

Not much anything new to me.