Lifespan: Why We Age―and Why We Don’t Have To

by David A. Sinclair, Matthew D. LaPlante, Ayumi Kajiyama

What if aging is not inevitable? In Lifespan, Harvard professor and renowned scientist David A. Sinclair challenges the conventional understanding of aging and presents groundbreaking research suggesting that aging is a disease—and one that can be treated. Backed by cutting-edge science, this book explores the biological mechanisms of aging and reveals how we may be able to slow, halt, or even reverse it. With a mix of scientific insights and practical advice, Lifespan offers a bold vision of a future where aging is no longer a certainty.

592 pages

Published September 16, 2020

About the author

David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.