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Kris Jensen #2

Night Plague

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Night Plague is one of the year's best thrillers” — BestThrillers.com

In the small town of Stevens Crossing, unexplained, terrifying domestic violence, murders, suicides, and road rage begin occurring. Whole families sleep poorly, and because insomnia seems to spread like an infection, Dr. Kris Jensen is asked to help the Health Department investigate.

Through interviews with affected families, local doctors, and the police, Kris learns that insomnia is often heralded by a peculiar rash, strongly suggesting an unknown virus disturbs sleep with deadly psychiatric consequences.
Thousands of visitors to an imminent town festival will risk multi-state spread of infection but Kris’s warning about transmission of a virus is rejected by town officials and her insomnia virus concern is ridiculed by outside experts.
Stevens Crossing turns against Kris with threats on her life, but she carries on and identifies two early insomniacs who may have been infected from a ring-tailed lemur possibly linked to a German neuropharmaceutical facility. As she works to gather more information, she encounters resistance at every turn.

Will Kris be able to discover the origin of the virus and determine how to stop it before it spreads nationwide?

338 pages, Kindle Edition

First published May 29, 2025

6 people are currently reading
1130 people want to read

About the author

Alex Lettau

2 books26 followers
Alex Lettau is the pen name of Ludwig Alexander Lettau M.D., an infectious disease specialist who currently lives and works in Charleston, South Carolina.

In practice for more than 30 years, he holds degrees from the University of Wisconsin, London School of Hygiene and Tropical Medicine, and Tulane School of Public Health and Tropical Medicine. Early in his career, Dr. Lettau was a medical missionary in Malawi (one year), Nicaragua (2 months), and Papua New Guinea (3 months). For two years he was a medical epidemiologist at the Centers for Disease Control in the Epidemic Intelligence Service (EIS) assigned to the Viral Hepatitis Branch of the Division of Viral Diseases.

Dr. Lettau has published (as first author) 20 scientific articles in medical journals and also published 15 short medical humor pieces on such subjects as “O.J. Fever Syndrome,” “Hepatitis Z,” and “J.C. is History” (the funeral of Joe Camel) in Annals of Internal Medicine, Infectious Diseases in Clinical Practice, and Stitches, a Canadian medical humor journal.

The medical thriller YELLOW DEATH is his first novel.

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5 stars
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9 (33%)
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Displaying 1 - 17 of 17 reviews
Profile Image for Matthew Elliot.
123 reviews25 followers
April 21, 2025
Acknowledgements and grateful thanks to NetGalley and Alex Lettau for the opportunity to read and review this e-ARC: 'Night Plague by Alex Lettau'. All opinions are my own and are not a reflection of the publishers and/or author, of which I have no association with.

Three out of five stars (3/5 stars).

Night Plague by Alex Lettau is a medical thriller about a little town with what seems to be anger issues but hosts a deadly secret.
THERE ARE NO SPOILERS IN THIS REVIEW.

TRIGGER WARNINGS: Animal harm, violence, and death.

Pre-Read:

//I read one of Alex's books earlier this year and I really enjoyed myself, so I am looking forward to approaching this ARC. Kris reminds me of Bones.//

Review:


"A virus that causes permanent insomnia triggers an ongoing outbreak of violence in a Southern town. Kris Jensen races to solve the epidemic before it spreads nationwide.. " — the GoodReads website for Night Plague.

— I adore outbreak stories and movies, and I enjoyed my first adventure with Kris.
I now understand why there aren't a lot of outbreak movies and books without zombies. No disrespect to Alex and his writings/profession but it can feel tedious reading them without a lot of action and / death and that can often be disrespectful to actual patients, survivors and or the people lost to similar ailments. Of course, an insomnia virus isn't exactly deadly and we spent the first half of the book interviewing other characters. Thankfully Alex has a great amount of knowledge of medical issues and then has the charisma to explain it to us in a way that is easy to read and understand.

I often find that authors that are in the medical profession often focus too much on labels and using the medical lingo and narrative which can often be confusing and/or long winded for most readers. Of course, I often lose myself in the language and terminology—I actually prefer it over people simplifying technology so others can understand. I like having to go and research terminology, new words and meanings, and Google really is your friend these days. You can even paste a bit of text into A.I. programs now and ask them to explain or deep dive and you can find out so much. Technology is so freaking amazing and I'm always in awe of it so why would I disrespect it by simplifying what makes it the most interesting thing to me.

That being said, Lettau managed to keep things interesting with his character conflicts, information gathering and even the back and forth of the interactions between Kris and the people she was interviewing was kept interesting and fresh.

You're probably noticing the three stars, hear me out. I should have paced the books further apart because I was still on a high from the first book I read which really blew my mind and left me wanting for more. I think I let that need win and I should have waited.

But. I would have missed out and that wasn't going to happen. Do you know how long, I personally, would have had to wait? I can't afford to buy anymore books, not right now.

So even though I am disappointed, I am not disappointed because it was a brilliant story with a tear jerking end (and a few moments in-between that we will NOT be talking about). Honestly, it takes a lot to be able to make me cry, even a few tears, unless you're a sad book / movie about dogs or a nappy advert, you're out of luck— most of the time.

ABOUT THE AUTHOR: Alex Lettau is the penname for Ludwig Alexander Lettau M.D., an infectious disease specialist who currently lives and works in Charleston, South Carolina in the United States of America. He writes novels in the thriller and horror genres and has a talent for writing intense character dialogue and medical scenes that engage and titillate his readers.

I sure was titillated. However, his first Kris Jenson novel is definitely my favourite. After talking to him, myself, I asked him why he'd decided to write the third book instead of the second and he showed great passion for his newest project with is always one of my most favourite things about authors — their passion for their writing, for their stories.

Despite the three stars, I would recommend this story of an insomnia virus if you like outbreak stories and novels filled with laughter, tears and mean action scenes.
Profile Image for Jannelies (living between hope and fear).
1,312 reviews192 followers
June 12, 2025
I'm very sorry but although I really wanted to give it a chance, there were just too many things I didn't like in it. Too much politics, too much religion, too much of several other issues.
Profile Image for Pattyh.
1,001 reviews
June 19, 2025
Thank you for the opportunity to preview Night Plague.
This is book 2?of a series but does well as a standalone.
A doctor is called in when a town has medical issues with the citizens.
As this doctor is experienced he unexpectedly ascertains that people are unable to sleep and are becoming violent.
Something is terribly wrong but this is not anything ordinary this is unexplainable. This is more horror than thriller but a good quick read with a few possible vampires thrown in.
3 stars
Profile Image for Jane.
1,272 reviews16 followers
February 12, 2025
There were lots of twists and turns throughout and well developed character. Would recommend this thriller..
Thank you to the author and NetGalley for the arc of this book
Profile Image for Amy.
160 reviews1 follower
July 19, 2025
So, I want to apologize to the author and publisher for a delay in reviewing this book, as i did receive an advanced reader copy and wanted to leave my honest review sooner. However, on to the book- the concept of this book is "outbreak of insomnia, depression and violence in a small Tennessee town thought to be related to a virus or other pathogen". I will admit that I do not think this book is for the average reader. I wouldn't necessarily classify the book as a "thriller" as much as it is a sort of procedural. Rather than a sort of "28 Days Later" type story, it's more of the Contagion level of a slow burn. Now, this is especially true for the first half or so (for which it took me about a week to read in short sprints), but it definitely picked up during the second half and did turn a bit more into a thriller.
Things I liked: I thought Kris was really empathetic and honestly the ideal researcher for this town (maybe too ideal?). Dan was great but I really enjoyed the dorky IT guy Paul even more. It was heavy on the medical and statistical jargon at times, but I loved that aspect- that is why I watch science fiction type movies, to appreciate the way they integrate known science with hypothesized science. I also really thought the story was well developed and slowly revealed in a way that felt like I was really helping to unearth the mystery in the town. And while the town was dangerous and Kris got into some sticky situations, I didn't recall feeling like specific ones were unrealistic- like this is a small town with a dwindling police force ability and increasing vigilante activity, which almost led to the sticky situations.
I didn't always like how over-explained things were. It took until about halfway before they stopped writing out her explanation of her goals with the research, and I had already understood that by about the third interaction. At times, it felt in a weird way like propaganda for a sort of 'good sleep cures all', but then they did use real medications as well so it balanced that out.
Overall, if you want a sort of medical procedural thriller, this book could be for you. I'd give it a 3.5/5 (rounding up), because while I felt that a few moments felt slow, the story was really well planned and written. I actually need to now go back and read the first story by this author!
Profile Image for Aimee (Book It Forward).
392 reviews19 followers
January 5, 2025
I really enjoyed this book – it was a fun and entertaining read that kept me engaged throughout. The story had a great premise that immediately pulled me in, and I especially appreciated the strong, independent female lead. Her character was well-developed and refreshing to follow.

That said, I felt like the book could have benefited from being a little shorter. While the rich details helped build the world and characters, there were moments when the narrative went deeper than I felt was necessary. I found myself skimming through some of those sections to get back to the main plot.

One thing that surprised me – I didn’t realize until I sat down to write this review that this is actually the third book in a series! I can confidently say that it reads very well as a standalone. I never felt lost or like I was missing key information, which speaks to the author’s ability to weave a complete and satisfying story within this larger world.

Overall, I’d recommend it to anyone who enjoys character-driven stories with strong leads and a compelling plot. I might even go back and check out the first two books now that I know this is part of a series!
Thanks to the publisher and NetGalley for the ARC!
Profile Image for Jackie McMillan.
451 reviews27 followers
January 18, 2025
I don't like heavy religious content in books. I wouldn't read a book about Christians, so I felt a bit duped by so much praying in what is pitched as a virus novel. Frankly I think religion should be a private matter so if an epidemiologist started praying in front of me, I would probably feel just as angry as I did about the turn this book took.

Night Plague centres on an epidemiologist, Kris Jensen, who used to work for the CDC and is invited to a town called Stevens Crossing to help unpack what is causing an avalanche of violence. It is heavy in medical jargon: "Most often a respiratory or GI illness with a high crud titer" or "He corroborated that the cirlicue rash is circumdemic that the author makes no attempt to explain. The descriptive writing leaves a lot to be desired: "Dr Emmit Hardy was a large African American man, 6 feet 6 inches tall." While it gets going in the middle, it peters to an end in a church service as a way of wrapping up the impact of the epidemic with each character in turn approaching Kris to explain how their story ended (crude). She hands them a business card (awful). I would only recommend it to confirmed virus novel fans. I think the heavy religious content should be mentioned in the description.

With thanks to NetGalley and Alex Lettau for sending me a copy to read.
Profile Image for nickiknackinoo.
665 reviews7 followers
July 2, 2025
Night Plague by Alex Lettau is an interesting story following a doctor who is called in to help a town when things are starting to go awry,
Kris Jensen, a doctor who specialises in infectious diseases, is contacted by her friend Dan to come to his hometown of Stevens Crossing, to help them work out what is going on, as many residents are becoming increasingly violent and people are getting injured. Otherwise suicidal thoughts are becoming high on their list of problems.
Kris gets straight to work gathering evidence to help with the theory that Dan and some of his other health colleagues think it is….a virus that may have originated from a lemur.
This was a good plot and it started off well, but it seemed to slow and become hard work for me to stay focused on. The characters were interesting, but Kris was the main character., as this story and the previous one are based around Kris and her work.
It may be much better for others to read than me, and I’m sad as I know how much work goes into writing a book.
Many thanks to Bronzeville Books for the opportunity to read this arc copy via Netgalley. My opinion is my own.
#Netgalley, #BronzevilleBooks,, #Alex Lettau.
Profile Image for Reed Jones.
212 reviews1 follower
April 3, 2025
Thank you to NetGalley and the author for the advanced reader copy! All thoughts are my own:

Night Plague follows infectious disease doctor Kris as she tries to investigate an insomnia outbreak that is causing widespread violence in a small town in the south.

The prose of this book actually made this a pretty accessible book, despite all the medical talk. Rather than feeling locked out, I was drawn in and interested in the medical talk throughout most of this book. I’m no medical expert, so don’t expect me to have researched how accurate any of it is, but the author is an infectious disease specialist, so I’m definitely gonna trust it.

I think towards the middle of the book, the story got a bit dull as it was mostly just interviews and theories, but I also understand that to be a necessary component in this particular story. I just think it was drawn out a bit long.

The resistance Kris faces throughout her investigation is unfortunately too close to reality in many ways. Very well written and interesting story. Would definitely recommend.
Profile Image for Kelly Brewer.
134 reviews14 followers
August 9, 2025
Well shoot I picked up this here ebook Night Plague and let me tell ya it done got me sittin up half the night readin like I aint got nothin better to do.

It’s bout this little ol town Stevens Crossin where everbody start actin plum crazy like folks fightin each other hollerin wreckin cars doin all sorta bad stuff cause they cant get no sleep. They scratchin at this rash that pop up on em, and then this doc lady Kris she get drug into it tryin to figure out why everbody losin they minds an not sleepin.

She go talk to folks, doctors, cops an all that, but the big shots in town they dont wanna hear none of it. They just worried bout their big festival comin up an they act like she just makin it up. Then them folks start threatenin her, tryin to run her off, but she just keep diggin anyhow.

It gets wilder by the page cause there might be some kinda crazy germ runnin round from some place over in Germany, and next thing you know its a whole mess. I swear I was turnin them pages like I was in a race and I aint never guess the twists comin at the end.

I give it 5 outta 5 Catfish!
471 reviews9 followers
June 18, 2025
In Stevens Crossing, insomnia is spreading like an infection, and the onset of sleep trouble is often heralded by a peculiar rash. Kris suspects the insomnia is caused by a new virus—a theory supported by visits with local doctors, the Health Department director, and the police chief.
As the town becomes more dangerous with many citizens armed and police having trouble keeping up with the escalating violence, Kris determines that one early insomniac may have been infected by a lemur when she learns that some lemurs can exhibit cathemerality – irregular sleep-wake patterns which she theorizes could be due to an insomnia virus.

This was an okay read but with far too many acronyms for me. Lots of religious stuff which I don’t do. It didn’t really work in my opinion.
Profile Image for Matt Egan.
640 reviews6 followers
January 11, 2026
An outstanding medical mystery!

Night Plague, the 2nd book in the Kris Jenson series of medical thrillers, recounts the story of a small town in which, inexplicably, sees its citizens being unable to sleep, causing a huge increase in month over month deaths related to the mystery pathogen. Epidemiologist Dr. Kris Jenson is brought in by an associate to find out what is happening, and is dumbfounded by what she finds. The writing is excellent, with a great heroine in Kris, and extremely entertaining secondary characters like Ruby. The plot is outstanding and matches up perfectly with the plot. Overall, 5/5 stars, highly recommended for fans of medical thrillers and thrillers overall!
Profile Image for Gail.
144 reviews
June 15, 2025
Thank you to NetGalley, the author and publisher for sending me a copy of Night Plague to read and review.

This was my first book by this author, and I enjoyed it. I love anything with virus/illness/end of the world vibes.

This is book 3 in the series with the same main character I believe, which I didn’t know until I had started the book. However, it can easily be read as a standalone, I didn’t feel lost at any point with previous information I had missed.

Overall, a decent, quick read and a solid 4 stars.
Profile Image for Beth Ann.
51 reviews1 follower
January 5, 2025
This was a great story and plenty of mystery. Gave 3.75 stars because it lagged a bit in the end. Not sure if this is a standalone or is the main character a repeat book’s focus. I learned a lot about infectious diseases and interesting subject of Fibromyalgia which I struggle with. Would read more from this author. Thanks for the Arc
839 reviews2 followers
March 30, 2025
This is my first book by this author. and was intrigued by the book's plot about an unknown virus. I work in healthcare and I enjoyed all of the medical details although they may be a little too technical for a lay person. Overall it was a good read with some suspense and plot twists that kept me guessing.
Profile Image for Janet.
1,453 reviews41 followers
August 31, 2025
This was a good story. This was a Goodreads giveaway winner.
821 reviews12 followers
February 12, 2025
I love a good zombie story this looks like this might be similar I’m having surgery today just the right opportunity to read something light
The story follows an infectious disease doctor who arrives in a small American town to investigate an outbreak of insomnia associated with violence and antisocial behaviour.i was not aware of this series of books but I think this doctor is the recurring character .altgoygh part of a series this book works as a stand alone novel
The author has a clear easily read prose style the book was a relaxing read despite its subject matter
There are times towards the middle of the book when it felt rather dull like reading an epidemiology lecture
Thos is probably because I am a doctor and this reminds me of uni lectures
I read an early copy on NetGalley uk in return for an unbiased review
The book is published in the uk on 1st July 2025 by Apex Lettau
Thos review will appear on NetGalley uk ,StoryGraph .and my book blog Bionicsarahsboojs.wordpress.uk
Displaying 1 - 17 of 17 reviews

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