Jump to ratings and reviews
Rate this book

Ether Day: The Strange Tale of America's Greatest Medical Discovery and The Haunted Men Who Made It

Rate this book
Ether Day is the unpredictable story of America's first major scientific discovery -- the use of anesthesia -- told in an absorbing narrative that traces the dawn of modern surgery through the lives of three extraordinary men. Ironically, the "discovery" was really no discovery at all: Ether and nitrous oxide had been known for more than forty years to cause insensitivity to pain, yet, with names like "laughing gas," they were used almost solely for entertainment. Meanwhile, patients still underwent operations during which they saw, heard, and felt every cut the surgeon made. The image of a grim and grisly operating room, like the one in Mary Shelley's Frankenstein, was in fact starkly accurate in portraying the conditions of surgery before anesthesia.

With hope for relief seemingly long gone, the breakthrough finally came about by means of a combination of coincidence and character, as a cunning Boston dentist crossed paths with an inventive colleague from Hartford and a brilliant Harvard-trained physician. William Morton, Horace Wells, and Charles Jackson: a con man, a dreamer, and an intellectual. Though Wells was crushed by derision when he tried to introduce anesthetics, Morton prevailed, with help from Jackson. The result was Ether Day, October 16, 1846, celebrated around the world. By that point, though, no honor was enough. Ether Day was not only the dawn of modern surgery, but the beginning of commercialized medicine as well, as Morton patented the discovery.

What followed was a battle so bitter that it sent all three men spiraling wildly out of control, at the same time that anesthetics began saving countless lives. Meticulously researched and masterfully written, Ether Day is a riveting look at one of history's most remarkable untold stories.

288 pages, Hardcover

First published August 1, 2001

43 people are currently reading
2144 people want to read

About the author

Julie M. Fenster

27 books15 followers

Ratings & Reviews

What do you think?
Rate this book

Friends & Following

Create a free account to discover what your friends think of this book!

Community Reviews

5 stars
68 (22%)
4 stars
112 (36%)
3 stars
88 (28%)
2 stars
35 (11%)
1 star
4 (1%)
Displaying 1 - 30 of 35 reviews
Profile Image for Vanessa.
30 reviews2 followers
May 31, 2016
Ether Day tells the stranger-than-fiction story of the men who were involved the invention of ether. The subject matter is fascinating - it's wild to think about life before anesthetics and how much medical practice truly changed with stronger solutions to pain. We really take for granted that anesthesia is safe and accessible.

There's a heavy focus on the legal aspects of the discovery - if you're interested in the history of patent law, this'll be a great read for you - and also the lesser-known aspects of the lives of the men who claimed to discover it. You won't find anything about William T. G. Morton's early days as a con-man through more cursory research, for instance.

This is also a delightful read if you're a medical history nerd who comes from Boston. Many of the places (from institutions to streets) mentioned are still around today.

While I liked the book overall, I had trouble getting into Fenster's writing style. I wouldn't say it's dry, but the book didn't grab me quite as firmly as some of the other medical histories I've read. It's difficult to put my finger on. This didn't spoil the book by any means, but it just wasn't a page-turner for me.
June 9, 2016
This review originally appeared on my blog at www.gimmethatbook.com.

Thanks to the author for gifting me this book for review!

ETHER DAY is meticulously researched; the characters are brought to life via the detailed descriptions of their lives and mental states.

To think that people were operated on with no care for their pain, yet Laughing Gas (ether) was used by non medical people for fun and escape, is mind boggling. No one made the connection between the two until William Morton, Horace Wells, and Charles Jackson “discovered” the other uses of this gas.

The fact that these three men’s lives overlapped was both good and bad: the discovery of ether as an anesthetic made both patient’s and surgeon’s lives better, but there was a lot of vitriol and ego involved as well. Each stood to make his fortune via ether, yet their lives were not always brightened by their actions.

Fenster has clearly done her research: there is both an index and endnotes, showing the comprehensive reading she did to recreate this story. She also includes a bibliography for further reading. The 1800’s come to life under her expert prose and background detail. I especially enjoyed the explanation of how the gas was delivered, and how the machines were tinkered with to provide a more accurate mixing of gas and air. The fact that these men experimented on themselves shows both folly and determination – in Chapter 14, Chlory, there is a section about scientists sniffing different concoctions of gases to figure out the best combination.

Every Thursday evening they would gather at the Simpson home, sitting around the dining table to inhale candidate chemicals. “I selected for experiment and have inhaled several chemical liquids of a more fragrant and agreeable odor,” Simpson wrote in a medical journal during the course of his research, “such as the chlorine of hydrocarbon, acetone, nitrate of oxide of ethyle, benzin, the vapour of chloroform, etc.”

One old friend, a professor named Miller, made a habit of dropping by at breakfast time every Friday, so he said, to see if anyone was dead.

The lengths these men went to in the name of science is unheard of today. As the book jacket notes, Ether Day is a little known anniversary, yet without the actions of these men there would have been greater suffering in this world. They were not heros, either – just men trying to make money or a name for themselves, who fell into a bizarre chain of events that would send them all down a crazy rabbit hole and eventually break them.

Author Julie Fenster has brought the memory of these men out of the past and placed it firmly into our awareness with ETHER DAY. I commend her for choosing her subject wisely and keeping this discovery relevant, in a new way.
34 reviews12 followers
September 20, 2010
Really interesting... was psyched that on page 5 they introduce William Morton as one of the men responsible for figuring out how to use ether for surgery since Morton is a family name and there's a chance he's a distant relative.

Until they reveal that he was wanted in 5 states for fraud and spends the whole book trying to get credit for something he likely didn't have much to do with discovering. I have to admire his gumption, at least... go Mortons! Luckily he didn't kill anyone.



Profile Image for Kay.
1,020 reviews216 followers
August 3, 2007
Fairly interesting -- a tangled tale about three men, all of whom claimed the invention of ether. The book interweaves the tale of the three men with information on surgical procedures of the time. Needless to say, the development of anesthesia was an incredible boon. I'd have preferred more medical information, however, than biographical information.
Profile Image for Trisha.
29 reviews
February 18, 2012
Having read about 30ish books for my Writing class about the discovery of anesthesia, this has to be one of the most interesting out of them all. Even for someone who isn't interested in science, dentistry, etc., I think this book would still be compelling.
Profile Image for dejah_thoris.
1,351 reviews23 followers
September 20, 2017
The strange but wonderful story of how ether began the revolution of anesthesia in medicine. Thank goodness dentists were willing to try it! A great controversy surrounded who developed it too. Definitely an interesting but approachable read.
26 reviews
April 15, 2011
Interesting historical perspective on the discovery of anesthesia especially considering all of the other famous people involved, including Ralph Waldo Emerson and Samuel Morse.
Profile Image for Kathy.
980 reviews5 followers
July 8, 2019
This showed up in a monthly library magazine and caught my eye. Had to be ordered through inter library loan and came from Western Pennsylvania. A slow sometimes monotonous read. I found the medical history a bit tedious at times but informing. What I find interesting is that Ether is a preferred gas well into the 21st century.
Profile Image for loupgarous.
12 reviews
August 1, 2018
This book by American Heritage magazine columnist and New York Times contributor Julie M. Fenster is a remarkable account of the history of modern anesthesia (a word assigned to the procedure by no less than the estimable Daniel Webster) and the lives of the men who worked to gain its acceptance in the medical world.

Fenster has a wonderful dry wit, which comes in handy when describing the antics of William Morton - the mountebank and physician manque who aimed to make his fortune selling an orange-scented version of common sulphuric ether (named in what seems to be the first trademark of a medical good, "Letheon") and who left a record of swindles and business fraud ranging from New Hampshire to New Orleans before demonstrating to the physicians of Massachusetts General Hospital the usefulness of ether in surgery - largely removing its greatest terror, unrelieved pain.

While effusive in her praise of the procedure of anesthesia itself, Fenster gives us wonderful "warts and all" portraits of the major personalities who jockeyed for the title of "inventor of anesthesia," which included William Morton and at least two respected New England physician-scholars. The venues for this struggle included the United States House of Representatives (where certain Representatives fought to get their state's "favorite son" recognition and money for the distinction of giving anesthesia to the world).

This is a wonderful history of anesthesia as we have come to know it, in that early stage where it dramatically improved the lot of surgical patients with chemicals which before then were scientific curiosities used mainly for the entertainment of the middle class as then-legal recreational drugs.
Profile Image for Magill.
503 reviews14 followers
February 10, 2012
I quite liked this book, unexpectedly lent to me. Having read a fair amount of non-fiction history, I thought the author did a pretty good job at bringing the main characters to life. Ether Day was almost a minor role in what played out for many years between the men who wanted to be acknowledged as the person who introduced ether to the medical world. The stories of the men and their personalities were quite vivid and surprisingly dramatic. The story of ether was also a surprise, as I had been unaware of the prevalence of social use of ether prior to Ether Day. The science of ether and the medical use was more like mortar between bricks, not taking up a lot of the book, but it was nicely integrated and provided the structure to explore the responses of the medical profession in other places besides Boston, where the 1st hospital use is likely to have occurred. I would go for a 3.5 here, as I think the book was quite interesting for such an unexpected topic.
Profile Image for Keli.
592 reviews10 followers
February 9, 2017
I first heard about this book on NPR in 2001. The story was fascinating, a conman dentist made one of the most revolutionary discoveries in modern medical science and no one has heard of him. Plus, there's this endless feud between the various men who claim the discovery and its effects on the establishment, in both science and class, and the monetization of medicine. The sell was great. I remembered the author's name for weeks before I bought the book, where once purchased it sat on a shelf for years. It moved with me from Texas to South Dakota to London. I've meant to read this book for 15 years! Though it was very interesting and it had me laughing, well snorting, out loud, it wasn't a breezy read.
I'm not sure if it was the writing style or the references but something just didn't click.
Profile Image for Anthony.
55 reviews8 followers
May 3, 2008
Ether Day is a fascinating look at the history of anesthesia. (even if you’re not an anesthesiologist…) Think about it, the first clinical use of general anesthesia in the surgical arena was just over 150 years ago. This is an amusing and educational look at the history of what is arguably the most important medical advancement in the history of mankind. This book will interest anyone who has ever had surgery, plans to have surgery, has an interest in medicine or history, or just likes to know stuff.
Profile Image for Meg Marlowe.
5 reviews1 follower
January 30, 2016
One of the BEST books I ever read! Julie M Fenster also scored big with Case of Abraham Lincoln: A Story of Adultery, Murder and the Making of a Great President. Just such riveting writing. This is a just a little masterpiece though: while learning history, we also delve into the human psyche, it's dark penchants and addictions. Just fabulous!
Profile Image for Paul.
4 reviews
September 4, 2014
I really liked how the author was able to take the facts from history and make it a very readable and almost fiction like story. I really enjoyed reading the book as well as gaining that knowledge in this way. I felt near the end it got repetitive and boring but that was partly because of how the men's lives ended.
Profile Image for Ethan.
1 review
January 7, 2019
Fascinating tale, well researched with just the right depth of topic. The structure was not the smoothest but only distracted very slightly from the story arc. A brief and interesting look into the world of invention and medicine. Worth the short read.
Profile Image for Kayla.
574 reviews1 follower
July 12, 2011
interesting read...especially if you have just come out of surgery:)
Profile Image for Dennis Ross.
42 reviews4 followers
August 13, 2012
Fascinating history of anesthesia; a selection for my science book club Oct 2012.
Profile Image for Stanley.
246 reviews5 followers
July 18, 2015
This is an interesting and informative read.
Profile Image for Niki.
3 reviews
March 2, 2014
Heard about this from Radiolab. An interesting medical, historical and sociological tale.
Profile Image for Michelle Mclain.
7 reviews3 followers
August 31, 2014
"Whenever it is that self-abandonment is no longer natural but must be induced, childhood ends..." -referring to Ether parties held commonly in the early 1800s.
Profile Image for Lo.
248 reviews41 followers
November 15, 2015
Everything I expected, but so much more.
Profile Image for Joette.
129 reviews
January 15, 2009
This was absolutely fascinating. Kids had ether parties, not drinking parties.
Profile Image for Emily.
283 reviews5 followers
February 19, 2022
I thought Julie Fenster's "Ether Day" was a great piece of medical history. You do not need medical background to understand either the pretext or the story. By staying closer to a biography and following the controversy related to who was named on the ether patent, Fenster stays from going deep into the science. This isn't to say that she doesn't touch on it and there are references for follow-up. Many fields of science were in their naissance during the period the book covers and the cast of characters frequently had their hands in more than one pot. The result is a book that may be over broader interest in the history of science, particularly in the US through in the period leading up to and during the Civil War. However, Fenster has also beautifully illustrated how information about a discovery proliferated before mass media. This is something quite amazing to encounter in the COVID times.
Medical anesthesia may be the greatest of all discoveries in medical science. We simply can not comprehend life before anesthesia. We consider access to anesthesia a right. Prior to the existence of anesthesia doctors never believed such a thing was possible, some even thought it would detract. The result was that no one was actually looking. Various chemists and doctors had become aware of the anesthetic values of both ether and nitrous oxide, but no one considered pursuing them seriously. Medical students, amongst others used both to get high, in fact, there were various points before the discovering of anesthesia that you could hire a chemist for an ether or nitrous oxide party! The use of nitrous oxide and then ether for surgery where in fact put forward by dentists... hmm... they must not be all bad. These are just a few of the gems hidden in "Ether Day"!
Profile Image for Kathleen.
674 reviews
January 24, 2024
A friend lent me this book. Truth be told, I was worried it would be a difficult subject to enjoy. Although it lags in several sections, it is not a novel, but a work of nonfiction. The story itself is fascinating. Ether was such a breakthrough and a very basic introduction of anesthetics. For before this discovery, any type of surgical procedure was an excruciating experience with just pain medication given to the patient The book not only tells the story of the ether and its surgical use, but of the three men surrounding its inception. The book also delves into the relationship of these three men--Morton, Wells and Jackson. Each of them had a personal agenda. One was a con man who wanted fortune, one wanted to benefit medicine and science and one wanted all the notoriety...not sure any of them achieved their goals. nterestingly, I am told Ether Day (October 16, 1846) is celebrated at Mass General and the Ether Room where the first surgical procedure took place is available to tour.
Profile Image for Casey.
925 reviews53 followers
October 14, 2020
An interesting medical history with plenty of human drama and eccentric characters. The story did drag a bit toward the end as I began to lose interest in the three men's interminable efforts to claim credit for this amazing discovery. My opinion? All of them deserve the credit, and a few more! Despite the initial (and unending) chaos, the discovery was made and we can all be thankful for that!

A recommended read.
Profile Image for Montage Matt.
41 reviews
Read
February 25, 2021
Ether and Nitrous oxide - what we call anesthetics - were not used in America until 1846. Prior to that such gases were used at parties to get high. True story. This book traces the three doctors [in the Boston region] who first posited and used ether to positive effect to help patients get through surgery.
Profile Image for Lila Monson.
6 reviews
August 2, 2025
I don't normally read non - fiction books, but I had to read this one for a project in English class 🙄. It was actually pretty good and it didn't even feel like non - fiction. It had a lot of drama and honestly pmo when I later looked up who was credited for the discovery of anesthesia because he's a wee scumbag in the book lol.
Profile Image for Allison.
20 reviews
October 25, 2025
I like Fenster's writing style and learning about history so I will definitely be picking up another one of her books. It seemed a little repetitive sometimes but I really like how she tied in things such as the Mexican American war, patent law and medicine.

You'll like this if you like Sam Kean (The disappearing spoon).
Profile Image for Margot B.
6 reviews1 follower
November 18, 2023
A very thorough account of the discovery of ether and the legal controversies surrounding the claim to this credit. It’s really interesting and, as I say, very thorough — but perhaps thorough to the point of tedium in many chapters.
Displaying 1 - 30 of 35 reviews

Can't find what you're looking for?

Get help and learn more about the design.