This revised and expanded edition includes a CD with all exercises and WinNonlin model/ command files. According to a review in the European Journal of Pharmaceutical Science , this book raises the stature of PK/PD modeling to its highest level.” This “essential” professional resource is regarded as the most comprehensive and practical guide to the design, analysis, and interpretation of kinetic and dynamic experiments. It provides the expertise needed to resolve commonly appearing problems with a pedagogic yet accessible approach. For many years a staple in both undergraduate and graduate classrooms , this updated edition adds new case studies to support basic concepts in PK/PD.
This is a truly dreadful book. Concepts, my ass. A hideous, unilluminating laundry list of recipes on which programs to run to fit specific models, with no effort to explain which model might be appropriate, or why one would even contemplate modeling to begin with.
Rowland and Tozer remains by far the best pharmacokinetic textbook out there.