The road trip to Hell starts with a stolen car. Stan and Mike take what they think is an easy trip to Florida to deliver a collectible Cadillac. Little do they know that they're hauling something much more important in their trunk. And everyone wants it: The Feds, the Catholic Church, a deeply spiritual - if sex and cocaine addicted - Cuban drug lord, and a desperate PI dressed as a truckstop hooker. Instead of a week prowling the beaches of Miami, they end up in a showdown on a sleepy Sunday morning in Savannah. It's high noon in the garden of good and evil.