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Aging: The Longevity Dividend
Scientists reverse cognitive decline in mice. "What reseachers are talking about is the first intervention that has the potential to slow aging in people. It would be one of the most important interventions in history." -Professor Jay Olshansky, professor of public health at the University of Illinois.
Extraordinary research, with potentially far-reaching implications discovers that giving young blood to older mice has a rejuvenating effect on certain brain areas of the old mouse. Researchers see a benefit for tackling certain degenerative brain diseases, others are going beyond this.
Extraordinary research, with potentially far-reaching implications discovers that giving young blood to older mice has a rejuvenating effect on certain brain areas of the old mouse. Researchers see a benefit for tackling certain degenerative brain diseases, others are going beyond this.
- GenresScience
Hardcover
First published September 1, 2015
19 people want to read
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September 11, 2019Nature's review: https://www.nature.com/articles/529154a
Excerpts:
"The chances of living to old age are higher than ever in many parts of the world. So, particularly in developed countries, health-care systems are struggling to cope with the 'silver tsunami' of elderly people with clusters of diseases for which age is the main risk factor, including cancer, diabetes, cardiovascular disease, sarcopenia and dementia. Fortunately, the opportunity is at hand to transform the landscape and keep people in better health as they age. . . .
Ageing, he shows, is not nature's way of making space for the young; rather, it is a haphazard process of decline. The discovery that it is malleable allows an entirely new approach to improving the health and welfare of older people. Lifespan might increase slightly as a result, but the crucial point is that morbidity could be compressed. Olshansky also shows how the conventional route of treating single diseases could, perversely, increase overall morbidity, because the longer people live, the greater the part played by ageing in health status. Interfering in mechanisms of ageing provides the current best prospect for preventing cancer, cardiovascular disease and dementia.
From a health-economics perspective, examined by Dana Goldman, the results of reducing morbidity in older people would depend on public policy. If older people were healthier and more active, then they would depend less on others and would produce greater economic activity — from work and volunteering — both of which would be a net benefit to society."
Excerpts:
"The chances of living to old age are higher than ever in many parts of the world. So, particularly in developed countries, health-care systems are struggling to cope with the 'silver tsunami' of elderly people with clusters of diseases for which age is the main risk factor, including cancer, diabetes, cardiovascular disease, sarcopenia and dementia. Fortunately, the opportunity is at hand to transform the landscape and keep people in better health as they age. . . .
Ageing, he shows, is not nature's way of making space for the young; rather, it is a haphazard process of decline. The discovery that it is malleable allows an entirely new approach to improving the health and welfare of older people. Lifespan might increase slightly as a result, but the crucial point is that morbidity could be compressed. Olshansky also shows how the conventional route of treating single diseases could, perversely, increase overall morbidity, because the longer people live, the greater the part played by ageing in health status. Interfering in mechanisms of ageing provides the current best prospect for preventing cancer, cardiovascular disease and dementia.
From a health-economics perspective, examined by Dana Goldman, the results of reducing morbidity in older people would depend on public policy. If older people were healthier and more active, then they would depend less on others and would produce greater economic activity — from work and volunteering — both of which would be a net benefit to society."
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