The year is 1484 and a vile devilry is at the heart of the holy Church. In a complex web of deceit and lies, our two Florentine adventurers combine forces with the mysterious and dangerous Spanish inquisition, and step into the murky world of Roman politics. Surrounded by heretics and traitors they engage in a desperate struggle to save Pope Sixtus IV, and with him, the hopes of the powerful Medici family. From the distant shores of Britain, a mysterious knight in league with the dark forces of Siena seeks to destroy the Medici bank for his own nefarious aims, whilst in Florence, a long forgotten enemy has risen from the ashes to begin a rebellion that would destroy the vice-like grip on power maintained by the Medici, and the fate of all hangs in the balance. The world is in turmoil, war is looming and only the strong will survive.