This short piece is a fascinating look at the way researchers are identifying the biological problems underlying mental disorders such as depression or OCD and finding non-invasive ways to correct those problems. These groundbreaking techniques have the potential to help millions of people in ways more effective than those already at our disposal. Furthermore, reading between the lines reveals that success with these specific treatments (for example, infrared light therapy or non-standard use of antibiotics) could lead to more creative ways to remedy medical problems with the brain.