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The Brain Defense: Murder in Manhattan and the Dawn of Neuroscience in America's Courtrooms

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In 1991, the police were called to East 72nd St. in Manhattan, where a woman's body had fallen from a twelfth-story window. The woman s husband, Herbert Weinstein, soon confessed to having hit and strangled his wife after an argument, then dropping her body out of their apartment window to make it look like a suicide. The 65-year-old Weinstein, a quiet, unassuming retired advertising executive, had no criminal record, no history of violent behavior not even a short temper. How, then, to explain this horrific act?
Journalist Kevin Davis uses the perplexing story of the Weinstein murder to present a riveting, deeply researched exploration of the intersection of neuroscience and criminal justice. Shortly after Weinstein was arrested, an MRI revealed a cyst the size of an orange on his brain's frontal lobe, the part of the brain that governs judgment and impulse control. Weinstein's lawyer seized on that discovery, arguing that the cyst had impaired Weinstein's judgment and that he should not be held criminally responsible for the murder. It was the first case in the United States in which a judge allowed a scan showing a defendant's brain activity to be admitted as evidence to support a claim of innocence.
The Weinstein case marked the dawn of a new era in America's courtrooms, raising complex and often troubling questions about how we define responsibility and free will, how we view the purpose of punishment, and how strongly we are willing to bring scientific evidence to bear on moral questions. Davis brings to light not only the intricacies of the Weinstein case but also the broader history linking brain injuries and aberrant behavior, from the bizarre stories of Phineas Gage and Charles Whitman, perpetrator of the 1966 Texas Tower massacre, to the role that brain damage may play in violence carried out by football players and troubled veterans of America s twenty-first century wars. The Weinstein case opened the door for a novel defense that continues to transform the legal system: Criminal lawyers are increasingly turning to neuroscience and introducing the effects of brain injuries whether caused by trauma or by tumors, cancer, or drug or alcohol abuse and arguing that such damage should be considered in determining guilt or innocence, the death penalty or years behind bars. As he takes stock of the past, present and future of neuroscience in the courts, Davis offers a powerful account of its potential and its hazards.
Thought-provoking and brilliantly crafted, The Brain Defensemarries a murder mystery complete with colorful characters and courtroom drama with a sophisticated discussion of how our legal system has changed and must continue to change as we broaden our understanding of the human mind."

336 pages, Hardcover

First published February 28, 2017

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Kevin Davis

11 books15 followers

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Displaying 1 - 30 of 81 reviews
Profile Image for Dave Cullen.
Author 9 books61.8k followers
March 1, 2017
I loved this book so much in galleys that it's the only book I agreed to blurb this year. I guess I'll post that here, since it forced me to be succinct:

The Brain Defense is a stirring ride into a fascinating new field. Can a tumor or traumatic brain injury explain rape or murder? Can they diminish culpability? If your instinct screams no, read page one. The first staggering case will challenge your assumptions; the book that follows may alter them permanently. The vividness and urgency of Kevin Davis’s storytelling, along with his artful touch, draw you in from the first line, and never let you go.
Profile Image for Ammar.
486 reviews212 followers
March 21, 2017
This book bad over 35% of it notes and sources. The last of the written chapters ended at around 62% and the rest was references and notes. That shows that it is well researched and the chapters alternate between the key case in the book and the history and development of neuroscience, psychology, psychiatry and its relationship to the law.

In 1991, Herbert Weinstein a sixty-five-year-old advertising executive with no prior history of crime or violence after an argument strangled his wife Barbara, opened the window and threw her out of their 12th-floor apartment. His defense team had a structural brain scan done using MRI and PET scan. The images showed a big piece missing from the prefrontal cortex of the brain, i.e., a subarachnoid cyst was growing in his left frontal lobe.

Did this growth cause Herbert to commit this violent crime ? Did it cause him to snap in his wife's face and murder her ? Was he able to understand what he did and did he know it was wrong ?

The author does a great job in answering those questions while connecting this case to the growing literature of cases past and present and how it influenced future cases since it was the first case to have PET Scans allowed as evidence.
Profile Image for Terri.
276 reviews
March 17, 2017
I have been very interested in the subject of traumatic brain injuries since my husband had a home accident in 2008, which caused him life-threatening head injuries. He has since recovered and is doing very well with zero side effects (other than a metal plate in his head.) However his brain surgeon wanted me to keep a close watch on him for personality changes. When I read a review of Kevin Davis's new book "The Brain Defense: Murder in Manhattan and the Dawn of Neuroscience in America's Courtrooms," I knew I had to read it.
The author explores a history of cases (of mostly men) whose personalities changed after they received either a TBI or had tumors/cancers in their brain. Were they morally responsible for any crimes they committed? How do we punish them? Should we bring this medical knowledge with us into the courtroom?
He tells the story of Herbert Weinstein, a sixty-five year old man with no history of violent behavior, who strangles his wife and throws her body off a twelve-story building. Noting his strange demeanor, his defense lawyers ask for a MRI of his brain and he is shown to have a cyst the size of a orange pressing on his frontal lobe. The frontal lobe of the brain governs judgement and impulse control. Could this man not be responsible for his wife's murder? His lawyers went with the insanity defense and he got seven years for manslaughter. This is the case that changed the American legal system regarding neuroscience.
Many questions arise when reading this book so I think this would be a interesting novel to discuss in a book club. Should criminals be excused because their brains made them do it?
Profile Image for Lynn.
337 reviews87 followers
June 4, 2017
This book explores the intersection between neuroscience and the law. Can and should lawyers use CAT Scans & PET Scans as evidence of brain disorders to mitigate the degree of criminal responsibility? What I liked: 1. The complicated material was well described. 2. I loved the case studies and real life situations. For example, a retired mild mannered man strangles his wife and throws her off a 13 story building. They discover he had a has a brain tumor, so is he guilty? The book keeps revisiting his case making it interesting and suspenseful. What I did not like: 1. The material presented is still soft science. 2. As a psychologist I already knew some of the information. 3. If you are looking for definitive answers, this book does not supply them. If you are looking for interesting stories and provocative information about the brain's role in crime you may have found your book.
Profile Image for Pam Mooney.
990 reviews52 followers
February 7, 2017
Fascinating and well researched with plenty of notes to support and follow up. I have read of these cases casually and enjoyed very much hearing the medical history and true story behind the scenes. Very comprehensive in the cases presented that involve neuroscience from criminal defense and prosecution perspective. I loved the presentation of each case as a story that you follow from inception to conclusion. I was drawn in and read straight through. A good read.
Profile Image for Lindsay Nixon.
Author 22 books800 followers
March 5, 2017
RIVETING! Most gripping nonfiction book I've ever read. That perfect balance of science, application, memoir/historical account with a "what-happens-next" suspenseful pace.

Most interesting tidbit: Military veterans suffer brain damage much like NFL players or boxers because they are near explosions that make them fall and hit their heads. This has never occurred to me. (The Movie "Concussion" is the perfect pair to this book).

I was also surprised (even as a lawyer) to learn how rarely the "insanity" defense is used in criminal trials... and how woefully unsuccessful it is (and why).

Finally, although this book does not come out and say this specifically, the dots connect throughout with one clear conclusion: the death penalty is not justice.

Life in prison? Sure, but that time in prison should also include therapy or other medical treatment that can repair the brain, if possible. "Faulty wiring" or "brain damage" is not an absolute defense in that it gives the person a pass or pardon. What it does provide is understanding. Our current legal system wants to access blame and personal responsibility with a focus on free will. Neuroscience changes that and change is difficult. Punishment is still warranted, but we need to start having more compassion and accept that these people "know not what they do."
Profile Image for Ross.
18 reviews3 followers
January 11, 2017
Disclosure: I won this book from a Goodreads giveaway.

I really enjoyed this book. I have always wanted to read books on landmark cases, so this is a good introduction. I would say for the most part that the author is objective in regard to this topic which can be rare these days. This book was way better than I anticipated. I am a layman in regards to law and neuroscience, but the author did a stellar job explaining various terms. I will look into this author's future releases; as long as, they are in the same vein.
Profile Image for Christina Dudley.
Author 28 books266 followers
March 24, 2017
While this book covered ground I've traveled in other brain books (the ubiquitous Phineas Gage puts in his usual appearance), it took the unique angle of tracing how neuroscience entered and has impacted the law courts. Author Davis uses the case of a middle-aged Manhattan man who got in a tussle with his second wife, strangled her, and threw her out their twelfth-story window as a jumping-off point, so to speak. Was it your run-of-the-mill crime of passion, or did the cyst pressing on Mr. Weinstein's frontal lobe make him unable to control the natural impulses that arose to fight back, when his wife clawed at him?

Along the interesting way we encounter lots of violent criminals, including a few NFL players. It's sad to me that, once you remove our inhibitions and "impulse control," what's left to us humans is basically awful behavior. Which means John Calvin was right, I suppose, and we are indeed depraved. Otherwise, why wouldn't removing our impulses and reasoning result in unexpected acts of kindness? Many of us are just one traumatic brain injury away from alienating our loved ones, taking up substance or gambling addictions, losing our jobs, and possibly flipping out and running someone through with an ice pick.

Read at your own risk.
Profile Image for Mike Bushman.
Author 8 books8 followers
March 5, 2017
Author Kevin Davis' deeply researched story of how neuroscience is being erratically grafted with our legal system is compelling and thought-provoking. Even though the brain, the law and neuroscience are complex topics individually, Davis makes sense of their integration while engaging us emotionally in the stories of people he writes about.

Told through multiple cases and from multiple angles, The Brain Defense is a must read for anyone interested in the law, mental health, public policy or brain injuries. For those interested in justice and philosophy, you'll also explore deep questions surrounding people whose brains become damaged through mental illness and physical brain injuries.

You might even find that it helps you better understand individuals in your own community, allowing you to contribute to and advocate for better outcomes than we are achieving today.
Profile Image for Darcia Helle.
Author 30 books737 followers
March 29, 2017
"My brain made me do it." Sounds like a ridiculous defense but, with this book, Kevin Davis shows us the science making that phrase a real possibility.

While I'm tempted to rehash some of the excellent material within, because it's a really fun topic to discuss, I'll instead stick to my thoughts on the book in general. First, the material is impeccably researched. The author builds from a solid base of one particular case, with a man who, after murdering his wife, was found to have an enormous cyst on his brain. From there, we explore what it means to be sane, and is the question of sanity different from being criminally responsible?

In reading this book, it's difficult not to question the issue of free will. How much of our behavior is governed by the inner workings of our brains? We start to wonder where the line sits between choice and biologically-governed behavior.

Kevin Davis's writing is thoroughly engaging. This isn't a dry, textbook kind of read. Yet, it's also not light pop science. The content is compelling and thought-provoking. Davis doesn't claim to have all the answers, and he doesn't lead us in any specific direction. He gives us room to ponder the questions and reach our own conclusions about a topic that is likely to become more controversial over the years.

*I was provided with an advance copy by the publisher, via Amazon Vine, in exchange for my honest review.*
Profile Image for Molly.
1,202 reviews53 followers
April 9, 2017
Really interesting history of the ways in which neuroscience has been used in courtroom defenses. The book is straightforward, engaging, and Davis doesn't shy away from the controversy and complexity surrounding the ethical issues surrounding defenses that are based on emerging understanding of scientific findings. Definitely worth a read.
Profile Image for Samantha Whitney.
87 reviews1 follower
January 27, 2025
this was such an interesting read. reading about specific cases of TBIs that could be linked to crime is a fascinating subject. i look forward to keeping up with the field of neuroscience as it is used in criminology
Profile Image for Reva Bajjuri.
42 reviews
April 13, 2025
Breezed through this one mostly bc I’m super interested in the topic but I learned lots and it reads very easily for a nonfiction
Profile Image for Holly.
1,067 reviews294 followers
April 7, 2017
Interesting overall but I was surprised that not a single woman's case was discussed. Isn't PMS still in the DSM?. The book might deserve 4 stars, but I just feel like it's a respectable 3 today. Wise to remember to be careful what you wish for in claiming an insanity defense: you may be stuck with a life sentence.
43 reviews34 followers
October 5, 2017
This is a book that explored the collaboration between neuroscience and law.

The ultimate questions that this book attempted to answer are, whether a person is responsible for his behaviour if he is not in his right mind? And are brain scans able to determine whether a person is sane?

The author presented us with a variety of court cases in which the defense attorney tried to mitigate the sentence received by the defendant through brain scan that showed a region of the brain which is diseased or underfunctioning. The cases describing the change of behaviour following brain trauma or disease are both fascinating and disturbing at the same time. It is fascinating to learn that a person is able to transform into another person with a totally different personality, while disturbing to know that a person that you loved is capable to harm or even kill you after a brain disease or trauma.

However,  some experts are skeptical towards the assumption that a brain scan result, that is obtained through imaging and calculation, might be able to determine the sanity of a person, and that the defect seen on the scan is able to explain away the crime of a person. I for once think that neuroscience is still too premature to jump to that conclusion.

I agree with the school of experts who think that neuroscience should not be applied to individual court cases as evidence but to help shape a law system that helps to rehabilitate people rather than incarcerate them. With the advance of neuroscience, there are still endless areas left to be explored, and many more fields that would benefit from this.
Profile Image for Diane Yannick.
569 reviews866 followers
December 31, 2017
Since I have a brain injury, this topic is of utmost interest to me. I seriously don’t think I’m going to murder anyone or need a lawyer to defend me using brain scans, but I did get kicked out of a department store once. This book is clearly well researched and reported. Repetitive sport assaults, as well as other brain abnormalities were investigated. Scientific data was often used in court to attempt to exonerate those who committed crimes. The author clearly examines the line between holding people accountable for their actions and understanding the mind of the offender. It is hard to know what the future holds as neuroscience continues to advance. I do know that this book was a slog for me.
Profile Image for Sheena.
247 reviews15 followers
June 11, 2021
Some interesting stuff here, but felt a bit disorganized. Definitely left me with lots to think about though...
Profile Image for Rachel Wall.
664 reviews
March 11, 2017
Audiobook during my commute this week. Extremely interesting look into mental health/brain function as explanations, not excuses, for crime. Some of the current studies are going on at Vanderbilt. If this subject interests you, I recommend. The cases are explained well for non legal or psychiatric expertise.
Profile Image for Anastasia Alén.
362 reviews32 followers
May 13, 2017
I very much enjoyed reading The Brain Defense, it's very well researched and written.

Can a tumor or a brain injury cause someone to commit a murder or to rape someone? Can they diminish culpability? When does someone plead for insanity and why it makes sense. I think doctors say that all tumors are individuals and that they have very different effects on people so I think Davis chose a very interesting topic to write a book about.

Davis also uses good examples, different bizarre and horrific stories of Phineas Cage, Charles Whitman, Herbert Weinstein & Ronnie Cordell among other.
Profile Image for Arnab.
50 reviews
April 7, 2020
Pros: Well-researched, informative and sensitive in its depiction of real legal cases.

Cons: Repetitive, unsystematic and structurally confused with two completely incongrous chapters and an extremely long final chapter (included maybe with an eye to shoehorning as much information as possible that could not be included anywhere else)
Profile Image for Mrs. Read.
727 reviews24 followers
May 27, 2024
The Brain Defense is a very impressive book. Its writer, Kevin Davis, is neither a neuroscientist nor criminologist; his degrees are in journalism, and it is probably because of this background that he writes in educated English and is able to explain certain complicated medical concepts reasonably intelligibly. His approach is very balanced - he interviews and quotes a large array of highly-regarded neuroscientists and some very committed defense lawyers. He uses a case study of a financially successful 70-year-old whose only criminal act in a lifetime is strangling his wife and throwing her out an 8th-story hotel window. Although all exams and tests show him to be mentally normal, a final MRI reveals the presence of a brain cyst the size of an orange. The question raised at his trial has to do with the extent of his culpability for the murder given this highly-unusual (and presumably disabling) condition. The writer shows that this brain-damage defense (PTSD, TBI, CBE, etc.) is becoming more common in death penalty legal arguments, and on the surface that is what the book is about.
As Davis acknowledges, this is only one instance of the unanswer[able] question of free will; of whether anybody actually chooses any course of action or always behaves as he does as the result of inexplicable, unpredictable chemical and/or electrical processes in a bodily organ. Do the concepts of crime, responsibility, benevolence, guilt (and on & on & on) have any meaning? Is “mind” something categorically different from (and more complicated than) “brain”?
A much less philosophical but probably considerably more practical question has to do with the problem of what to do with the shoplifter or home invader or kidnapper whose damaged brain relieves him of legal and moral responsibility for his crimes … and will likely compel him to repeat them? This difficulty is not unique to The Brain Defense; I’ve read several books on the woefully inadequate and abusive U.S. system and although some point out the futility of revenge, and all discuss the actual counterproductiveness of mass incarceration, none suggest a remote workable way of safeguarding society from the damaged - and damaging.
Needless to say, The Brain Defense is highly recommended, especially to readers with an interest in true crime or mental illness.

I could add pages of insightful quotations here, but I’ll confine myself to words from three different perspectives:

The legal system assumes that people make deliberate choices and what we choose determines what we do.

We [should] regard punishment as an aggrieved society’s path to emotional satisfaction and ‘true justice,’ … We should punish only to the extent that the punishment causes people—both the person punished and others who may be deterred—to behave better.

The Weinstein case is a glaring example of the misuse of neuroscience in the courtroom. It was, at its core, an insanity defense, concerning a person’s mental state and behavior Mental disorders are defined entirely by behavior … not by brain scans, so the question is always going to be—always—does whatever clinical or scientific information you’re trying to use help you answer the behavioral question or not?” A person’s mental state is based on observation and some clinical testing. So, he asks, does a brain image offer anything to help diagnose a mental disorder … the Diagnostic and Statistical Manual of Mental Disorders, fifth edition, the definitive reference work for mental health professionals, does not include biomarkers or references to brain scans to diagnose mental illness.


Profile Image for Natalie.
834 reviews63 followers
July 19, 2019
"Neuroscience could have an impact on the legal system that is as dramatic as DNA testing [...] Neuroscientists need to understand law, and lawyers need to understand neuroscience."

This book covered the intersection of neuroscience and law, tracing the history of its appearance within the courtroom and how that has influenced both judges and juries in terms of the verdict and sentencing for defendants. I thought that overall it was well researched and well written (there are a lot of notes and sources at the end of the book!) though I did unfortunately find that whilst it started off really strong (with the titular "Murder in Manhattan" case), it did seem to me that by the end things had kind of fallen to the wayside.

As a result of these developments, judges and juries are being asked to consider complex science, evaluate conflicting opinions about human behaviour, and ponder whether there is such a thing as free will.

For me, I felt that there were just too many people introduced without this and without sufficient background so that every chapter I was chasing the who of the present case, along with keeping track of the who of the previous case. And yet, despite just how many different cases there were in this... there were no female defendants at any point. And I truly want to know why. There has got to be cases where females have plead insanity (or temporary insanity) and had lawyers who presented brain scans (or other neuroscience-related material) as a potential defence. And if not... why not? Why was there no mention of women in this unless they were a researcher, the victim, or the family of the victim/defendant?

"If we have any ounce of humanity in us, it's not to excuse but to understand. I think it behooves us all to gain an understanding because if we don't try to understand, we'll never progress."

I think overall it was definitely interesting, but I couldn't truly immerse myself in this and 100% enjoy it. Started off strongly but I quickly found myself losing interest due to the many chops and changes. There just wasn't one cohesive narrative, or a clear succession between the cases and the stories behind them. Still, it was well researched and works well as an educational text, and I have to give credit for that.

"Humane treatment means that we regard punishment as a necessary evil, not as an aggrieved society's path to emotional satisfaction and "true justice". We should punish only to the extent that the punishment causes people - both the person punished and others who may be deterred - to behave better. Punishment that makes it harder for people to return to society as law-abiding, productive citizens should be eliminated - even if it feels good and right."
Profile Image for Cheryl.
608 reviews3 followers
June 9, 2017
As a science major who has always had an interest in law, this was a fascinating read. While there is no definitive brain injury that causes criminal behavior, there is a great deal of correlation between brain injuries, tumors and other brain abnormalities and people who demonstrate criminal behavior. The author deals with the difficult issue of using brain abnormalities as an excuse to absolve people from their own criminal behavior (as in not the not guilty by reason of insanity defense) and using brain abnormalities as a mitigating factor in judicial punishment. The author discusses various technologies such as PET scans, fMRI scans, EEG studies and SPECT (single photon emission computerized tomography) to explain how these technologies help scientists to understand how the “normal brain” is working in order to compare it to the brains of those who have committed serious criminal acts. While we have all heard of PTSD (post traumatic stress disorder) and TBI (traumatic brain injury), I was amazed at how much brain damage can be experienced by soldiers who are not visibly injured in an explosion (such as an IED blast) but who were in close proximity to the blast. An explosion triggers a very quick and intense rise in atmospheric pressure with sufficient force to push internal organs and then release them when the pressure returns to normal. Even if a soldier has no penetrating wounds and appears to be physically unscathed, the jerking of the head, along with the blast pressure can shear brain tissue, tear arteries, veins, connective tissue and as well as nerve fibers in the brain. A bomb blast can stretch, pull and twist neurons in the brain and cause serious brain damage. Combat veterans in Iraq and Afghanistan referred to it as the invisible injury. This type of injury changes behavior, ability to concentrate, impulse control and is correlated with aberrant behavior. The same behavioral changes have been found in NFL athletes who have experienced repeated concussions and suffer from chronic traumatic encephalophathy (CTE) as a result.

This area of science is, over time, going to have a similar impact on criminal law that DNA sequencing has had. Thought provoking read.
Profile Image for Amber Schroer.
374 reviews16 followers
November 17, 2017
Well written science based, true crime, but mostly research novel into the history and present state of neuroscience in the courtroom through the telling of the case of New York vs Weinstein - a 1992(?) case that first introduced the "broken brain" as a defense for a crime - more specifically- murder. Different than the "insanity" plea, this case was the first to use PET scans of the criminal showing a dramatic image of a large cyst in his brain that may have explained why a 65 year old, well respected, former "ad man" who had a clean criminal history and by all accounts - an all around "good guy" who had never shown any act of violence or aggression- would have violently attacked his wife after she had scratched him and then managed to throw her body from their 12th floor penthouse on the UpperEastSide.

The author uses research and other criminal cases to help readers understand Weinstein's case as well as question the idea of using neuroscience in the courtroom and for what reasons.

It is a very interesting book, but if you're expecting a retelling of the crime in the traditional true crime novel, you will be disappointed. This is not the purpose of the book, but rather it poses philosophical questions concerning neuroscience in the courtroom and the idea of free will bs free "won't ". He interviews multitudes of expert to really get into the depth of this idea that at first, to many, seems like a no brainer..."why wouldn't we want PET scans and MRIs in the courtroom possibly showing traumatic brain injuries or physical ailments that ultimately, no doubtedly could help jurors decide the fate of criminals who may not have had 100% fault in their crime?"
Well, my friend , their are several reasons with the biggest one being that neuroscience just isn't ready yet and the implications of that are shown throughout his case studies and interviews.
I particularly enjoyed the last section where he talks to "experts" who are using neuroscience in a profound way when it comes to sentencing and/or actually treating criminals rather than locking them up and potentially damaging their brain even more so that they end up more damaged.
1,004 reviews
July 25, 2017
In the last few decades, neuroscience has been uncovering phenomenal amounts of information about the brain. How may of our actions are due to choice? Is there such a thing as free will? The answer is that no one knows for sure - yet - but that does not stop gung-ho lawyers from bringing the latest research into the courtroom to excuse or mitigate their clients culpability.

Time and time again in The Brain Defense, Kevin Davis goes back to the case of Herbert Weinstein who killed his wife and threw her body out of their high rise window in 1991. The cyst on his brain was allowed into court as evidence though it ultimately did Weinstein no good - he was still found guilty - but he has been a topic of interest amongst neuroscientists and lawyers ever since. There is little agreement about the things claimed.

What impressed me most about The Brain Defense is how balanced the reporting is. Davis is as sympathetic to the lawyers arguing that evidence of a damaged brain is crucial to a good defence as he is to those who believe it is all smoke and mirrors. The brain researchers, too, are all over the map when it comes to opinion on whether their science belongs in the courtroom. Davis speaks to many of them, including experts on the juvenile brain, those studying athletes who have experienced multiple concussions, and researchers on PTSD; his exploration is extensive. The lay reader will come away from The Brain Defense with a lot more information than they started with and a lot of viewpoints to consider. It may even change their ideas about guilt and consequences.
Profile Image for Tracy St Claire.
338 reviews4 followers
November 3, 2019
This book was a well-written summary of brain imaging and criminal defense strategies in the United States for defendants with brain trauma or disease. It summarizes some case studies of those with trauma from football or war injuries, or tumors or other growths inside their brains and how the court system is and isn’t sympathetic to their defense.

The main case covered from start to finish was a man who strangled his wife and threw her from a twelfth-story window while she may or not been still alive. He has a large brain cyst but showed no other symptoms before or after of issues. Other cases involved pedophilia, mass murder and serial killers, and family abuse.

I started out this book being against the death penalty, and as a side note I have significant brain injury from multiple sclerosis. As I read these case studies, I realized that I am not very compassionate and sympathetic to these perpetrators who were abused as children, or injured or went through war and committed the horrific acts possibly beyond their control because of a brain injury. I was not there, even though the book sort of leaned in that direction, that brain injury can do that.

Maybe it was because these case studies were entirely men.

Throwing your wife out of a window in a high-rise building, $&*#@. No, no defense that you are OK now to walk safely in public, that it was a one-time thing. Jail for life at least in my opinion.
Profile Image for K. Lincoln.
Author 18 books93 followers
May 21, 2017
I'm a layman- not a scientist or medical professional of any kind.

Most of this book uses the framework of mild-mannered Herbert Weinstein who beat, strangled, and threw his wife out of a high-rise window one day over an argument, and spent most of the rest of his life in prison.

It turned out that Herbert had a kind of benign cyst that his defense lawyers tried to use as a mitigation factor in his sentencing. This is presented in the book as one of the primary cases where neuroscience imaging about the shape/state of a brain was used to suggest that leniency should be given to the defendant because of the question of how that abnormality intersected with free will.

That's a theme that is brought up throughout this book and its description of how neuroscience began to be used in U.S. courtrooms (mostly as mitigation defense during sentencing and not during the trial phase).

I found that question to be quite interesting, and also the discussions of how many scientists are deeply uncomfortable with making any kind of connection between the shape of a brain or presence of an abnormality and the responsibility for someone's behavior.

Interesting book, but I felt the focus on the Weinstein case somewhat limited the topic, and I wished for a bit more of the science behind the intersection of psychiatric diagnosis and the brain imaging.
Profile Image for Ptera Hunter.
Author 7 books12 followers
October 6, 2024
As we learn more about the inner workings of the brain, the issues of guilt and culpability become increasingly tangled. More and more often, neuroscience intersects with our legal systems, blurring the once-presumed idea of free will, muddying it with concepts of neurotransmitters, brain abnormalities, and the impact of the environment on the brain on responsibility.


In The Brain Defense, Kevin Davis explores this intersection. He follows both murders and situations where the violence triggered alarm bells before it was too late. However, he returns his focus to the case of Herbert Weinstein, who stood accused of killing his wife by tossing her from a window to simulate a suicide. Mr. Weinstein had a brain cyst that could have altered his behavior. Was he responsible for her death, or did the cyst make him do it? If we have a pathology potentiating a tendency toward violence, how culpable are we?


The book brings together law, neuroscience, and psychology in the case study of Mr. Weinstein and in the other examples used throughout the book. It explores free will and our doubts about the concept as it asks when and if “the brain defense” is valid and how we should proceed from there.
Profile Image for Yuki Fujinari.
7 reviews1 follower
April 27, 2024
I don't usually spend my days reading books about true crime, court cases or pop science. I find them to be either sensationalized bullshit to distract the masses or just simply not exciting for me personally.

No clue how this even showed up on my radar, but I ended up reading it. Easy reading, lots of anecdotes and historical context on both the legal history of insanity defenses and the evidence within neuroscience for brain damage leading to criminal acts.

Would I recommend this? It's entertaining and thought-provoking for sure. But again, I think all of us are better off reading about more substantial matters. You know...how capitalism and liberalism are fucking us in the ass everyday and are about to cause global collapse. As Marx called it, and I am no joke, literally quoting him: "the whole economic shit" (Die "ganze ökonomische Scheiße").
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