Rupa Sriyani Ekanayake started her writing career in 1999 by writing "Sausiri Sapiri Saudia” based on her experiences in Saudi Arabia where she accompanied her husband who was on a diplomatic posting, and served as a teacher.
In the year 2000, she wrote five children's books based on Jathaka stories ( the stories of Lord Buddah's previous births). The five books were: "Miulu Nuwara Pandiwaru" ; "Katusu Kare Raththaran", "Pinguththara; Kalana Mithuru" and "Aggala Liyamana". Her next book, "Dehshanuragaya" ( Patriotism) , published in 2002 , was a collection of short stories based mainly on her experiences as an officer of the Sri Lanka Administrative Service. She wrote two novels , Vijayai Kuweni and Senkadagala Maha Biso, in 2003 and 2005, respectively , both were based on the pathetic lives of two queens of Sri Lanka who had suffered for merely being heirs to the throne of the country. Her novel, "Tharu Bambasara" which was written in 2006, was nominated for the "Swarna Pusthaka Sammana" awarded by the Sri Lanka Book Publishers Association, annually.Rupa Sriyani Ekanayake launched her latest novel, Dutmi Nethin Kasup Nirind , in 2009, which depicts the aesthetic qualities of the life of King Kasyapa who built one of the nation's main heritages , Sigiriya, the lion rock.