As a grandmother, whose only grandchild, Aria, was just diagnosed with A-typical Rett syndrome, I found this so helpful. With my notebook at my side, I found myself taking copious notes. I will work very hard to research and find a cure. I am confident it is possible. We are very close. The human brain is so unique and complex. This manual gives us so much to be thankful for. What most of us take for granted, these Rett angels work so hard for. Thankful to Kathy Hunter and all contributors of this manual. Rosemarie