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Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Second Edition

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Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications teaches everyday biological data analysis to the undergraduate and graduate levels. Through numerous examples and over 100 tutorials, scientists learn how to use PK/PD seamlessly in a variety of practical areas, from simple plasma kinetics, multi-compartment models, nonlinear kinetics, plasma protein binding, pharmacodynamic models, turnover concepts, receptor binding, functional adaption and rebound, dose-response-time data analysis, inter-species scaling and a lot more. A substantial effort has been invested into the new pharmacokineticsand pharmacodynamics, including many new and updated Case Studies.

The text develops a logical, real-world approach to data and reasoning, showing the reader how to:


Think both analytically and visually about data Use graphics to make a point Impove your pattern recognition ability Make sound decisions Strategize your data analyses Appreciate more fully the exciting field of Quantitative Pharmacology

1040 pages, Hardcover

First published August 1, 1998

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Johan Gabrielsson

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Profile Image for David.
865 reviews1,664 followers
February 15, 2008
This is a truly dreadful book. Concepts, my ass. A hideous, unilluminating laundry list of recipes on which programs to run to fit specific models, with no effort to explain which model might be appropriate, or why one would even contemplate modeling to begin with.

Rowland and Tozer remains by far the best pharmacokinetic textbook out there.
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