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Broken Movement: The Neurobiology of Motor Recovery after Stroke

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An account of the neurobiology of motor recovery in the arm and hand after stroke by two experts in the field. Stroke is a leading cause of disability in adults and recovery is often difficult, with existing rehabilitation therapies largely ineffective. In Broken Movement , John Krakauer and S. Thomas Carmichael, both experts in the field, provide an account of the neurobiology of motor recovery in the arm and hand after stroke. They cover topics that range from behavior to physiology to cellular and molecular biology. Broken Movement is the only accessible single-volume work that covers motor control and motor learning as they apply to stroke recovery and combines them with motor cortical physiology and molecular biology. The authors cast a critical eye at current frameworks and practices, offer new recommendations for promoting recovery, and propose new research directions for the study of brain repair. Krakauer and Carmichael discuss such subjects as the behavioral phenotype of hand and arm paresis in human and non-human primates; the physiology and anatomy of the motor system after stroke; mechanisms of spontaneous recovery; the time course of early recovery; the challenges of chronic stroke; and pharmacological and stem cell therapies. They argue for a new approach in which patients are subjected to higher doses and intensities of rehabilitation in a more dynamic and enriching environment early after stroke. Finally they review the potential of four areas to improve motor video gaming and virtual reality, invasive brain stimulation, re-opening the sensitive period after stroke, and the application of precision medicine.

288 pages, Hardcover

Published November 3, 2017

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John W Krakauer

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Displaying 1 - 3 of 3 reviews
Profile Image for Ellie Ramsay.
20 reviews
April 22, 2025
Really great book. A very hard but interesting read. The author discusses interesting and controversial topics in detail relating to neurophysiology, neurorehabilitation, chronic hemiparesis and acute hemiparesis. Krakauer is able to effectively criticise both research and modern ideologies that surround these topics. Would definitely recommend !!
Profile Image for Michelle Chan-Cortes.
6 reviews2 followers
November 3, 2017
Far from a boring read, this was a wonderfully comprehensive history and review of where we stand today as far as stroke recovery and rehabilitation. Should be required reading for everyone in stroke and motor control! I feel that I will be using this as a reference guide for many years to come.
Profile Image for Kristina.
26 reviews
December 12, 2025
The most rigorous and comprehensive synthesis of motor recovery research I’ve read yet!!
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