Permafrost: Second International Conference, July 13-28, 1973 : USSR contribution

by Frederick Sanger

866 pages, Paperback

First published January 1, 1980

About the author

Frederick Sanger, OM, CH, CBE, FRS, FAA (/ˈsæŋər/; 13 August 1918 – 19 November 2013) was a British biochemist who won the Nobel Prize for Chemistry twice, one of only two people to have done so in the same category (the other is John Bardeen in Physics), the fourth person overall with two Nobel Prizes, and the third person overall with two Nobel Prizes in the sciences. In 1958, he was awarded a Nobel Prize in chemistry "for his work on the structure of proteins, especially that of insulin". In 1980, Walter Gilbert and Sanger shared half of the chemistry prize "for their contributions concerning the determination of base sequences in nucleic acids". The other half was awarded to Paul Berg "for his fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant DNA".

Frederick Sanger was born on August 13, 1918, at Rendcombe in Gloucestershire, the second son of Frederick Sanger, M.D., a medical practitioner and his wife Cicely. He was educated at Bryanston School and at St. John's College, Cambridge, where he took his B.A. degree in natural sciences in 1939. Since 1940 he has carried out research in the Department of Biochemistry at Cambridge. From 1940 to 1943 he worked with Dr. A. Neuberger on the metabolism of the amino acid lysine and obtained a Ph.D. degree in 1943. From 1944 to 1951 he held a Beit Memorial Fellowship for Medical Research and since 1951 he has been a member of the External Staff of the Medical Research Council. His present position is Head of the Division of Protein Chemistry in the M.R.C. Laboratory for Molecular Biology at Cambridge.

Since 1943 his work has been concerned largely with problems related to the determination of the structure of proteins. These studies resulted in the determination of the structure of insulin.

Sanger was awarded the Corday-Morgan Medal and Prize of the Chemical Society in 1951. In 1954 he became a Fellow of the Royal Society and a Fellow of King's College, Cambridge. He is an Honorary Foreign Member of the American Academy of Arts and Sciences; Honorary Member of the American Society of Biological Chemists, Member of the Academies of Science of Argentina and Brazil, Honorary Member of the Japanese Biochemical Society, and Corresponding Member of the Association Qulmica Argentina.

The brilliance of Frederick Sanger's work lies not in what he discovered but in how he discovered it. A skilled experimentalist, he developed novel techniques for sequencing proteins and DNA that revolutionized science and are still in use today.

In 1940, he married Margaret Joan Howe; they have two sons and one daughter.

More: http://www.nobelprize.org/nobel_prize...

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http://www.dnaftb.org/23/bio.html

http://www.nature.com/scitable/topicp...

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