Sherlock Holmes, the World’s Greatest Detective, along with Dr. John H. Watson, discover a terrifying secret. Dangerous criminals, destined for life in prison, or the gallows, are appearing on London’s streets. Prince Edward VII, future monarch of Great Britain, has informed Holmes that England faces a new menace. A Chinese warlord, by the name of Fu Manchu. Now, Holmes, and Watson, join forces with Colonel Denis Nayland-Smith, and Dr. Jonathan Petrie, in a desperate battle against the Tiger of Manchuria. With the aid of Professor James Moriarty-the Napoleon of Crime, they fight to preserve England from an insidious foe, bent on world domination!