Absolutely MAGNIFICENT.
This is precisely what literature is supposed to do: live and breathe. The journey from the prologue of Book One to the epilogue of Book Three led not only to the manifestation of a wondrous sound but that of a vision as well. The vision of a blind genius, no less! Oh, I had a qualm or two on stylistic and technical notes (like, why did such an abundance of words, especially when it came to the characters' dialogue, have to be emphasized with italics? and shouldn't there have been some explanation or even a word about Caterina's being nearly as articulate as a preteen at only four years old, unless I missed that detail?), but the SPIRIT of the story was unrushed, satisfying, and triumphant--miraculous without being over the top.
Beautiful book cover as well, though it's a pity Harvest House got the color of Michael Emmanuel's eyes wrong, especially when his eyes are such a major part of the story. But, that error is ultimately of little matter.
Aside from works by authors I know personally and John Nielson Had a Daughter (which may always be my favorite book for sentimental reasons), American Anthem may very well be the best piece of work I've read thus far by a 21st Century author. Certainly one of the greatest books I've ever read, period.