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The True Creator of Everything: How the Human Brain Shaped the Universe as We Know It

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A radically new cosmological view from a groundbreaking neuroscientist placing the human brain at the center of humanity’s universe

Renowned neuroscientist Miguel Nicolelis introduces readers to a revolutionary new theory of how the human brain evolved to become an organic computer without rival in the known universe. Nicolelis undertakes the first attempt to explain the entirety of human history, culture, and civilization based on a series of recently uncovered key principles of brain function. This new cosmology is centered around three fundamental properties of the human brain: its insurmountable malleability to adapt and learn; its exquisite ability to allow multiple individuals to synchronize their minds around a task, goal, or belief; and its incomparable capacity for abstraction.

Combining insights from such diverse fields as neuroscience, mathematics, evolution, computer science, physics, history, art, and philosophy, Nicolelis presents a neurobiologically based manifesto for the uniqueness of the human mind and a cautionary tale of the threats that technology poses to present and future generations.

376 pages, Hardcover

Published January 7, 2020

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About the author

Miguel Nicolelis

16 books84 followers
Miguel Nicolelis is the Duke School of Medicine Distinguished Professor of Neuroscience and Duke University Professor of Neurobiology, Biomedical Engineering, and Psychology and Neuroscience. In 2004, Scientific American elected him as one of the twenty most influential scientists in the world.

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5 stars
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56 (38%)
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25 (17%)
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14 (9%)
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Displaying 1 - 24 of 24 reviews
Profile Image for Nelson Zagalo.
Author 15 books459 followers
September 13, 2020
Miguel Nicolelis (1961) é um médico formado pela universidade de São Paulo e professor de neurobiologia na Universidade de Duke, EUA. A sua carreira tem sido recheada de prémios, reconhecimentos e louvores. Tornou-se popular com o “Projeto Andar de Novo”, criado para a abertura do Mundial de Futebol 2014 (Brasil), que por meio de um exosqueleto, interfaces cerebrais e inteligência artificial permitiu a um paraplégico andar, chutar e marcar um golo. O projeto fez correr muita tinta, dentro e fora da academia, mas o principal resultado está neste seu livro "The True Creator Of Everything. How The Human Brain Shaped The Universe As We Know It" (2020), sob a forma de uma grande teoria sobre a realidade e o cérebro.

... continua no blog: https://virtual-illusion.blogspot.com...
Profile Image for Elaine Aldred.
285 reviews6 followers
April 20, 2020
The True Creator of Everything is a book you have to invest some time in, because it’s dense with the type of narrative and data that takes some thinking about. Even with a background in science I had to apply all my powers of concentration to work through the conceptual complexity of the experimental work and conclusions.

I’ve never highlighted more passages in a book to go back to, but the herculean effort of reading the book was worth it, because what The True Creator of Everything lays out is something worthy of an intense and challenging science fiction novel with an expansive plot and cast. Except this is a work of non-fiction.

When I was at university (a longer time ago than I care to admit), much was made of how complex the different neurotransmitters of the central nervous system were compared to the peripheral nervous system. The received wisdom at the time was that these varied neurotransmitters hinted at how the intricate mechanisms of the brain worked and taking a closer look at them would answer all the unknowns.

This was soon found to be far from the truth. With the improvement in technology, intricate software investigations have forged their way into a whole new realm. Even so this book still raises more questions than it answers, but provides tantalising conceptual stepping stones to explore.

The True Creator of Everything does reassure us that we aren’t going to run into a HAL or a Terminator at our front door any time soon, because despite all the sophistication of AI programmes they are still too linear. As a biological organism, the brain can draw on far more resources than simple AI when it comes to the subtleties of output we experience in the outside world. Indeed, it is obvious to anyone who knows little about science but is prepared to stop and think about it for a moment, there is something very nuanced at work as we live our daily lives, which is far from linear and transcends a simple neuronal networking system.

This is where Miguel Nicolelis indicates his train of thought by considering that the energy from the sun that trees harness to grow and thrive, is dissipated into this living organism as embedded information in its physical structure. He calls this concept Gödelian information, named after the logician Kurt Gödel who demonstrated that formal systems have inherent limitation. In other words, a logical process of arguments which lead to a conclusion in a linear fashion is an incomplete way of thinking about a particular situation and there may be another non-linear way of thinking about it.

At least I think this is what it means, given my limited grasp of mathematics (I’m sure someone reading this post will be able to provide a better explanation I can insert in here). Thinking about the tree they encountered on their walk during a conference lead Nicolelis and his mathematician friend and colleague Ronald Cicurel to apply Gödelian principles to the function of the human brain.

Whereas digital computers dissipate all the work they do into heat, human brains pour this into storage of what Nicolelis calls Gödelian information. The more complex the organism, the more this will be done.

An added twist to this remarkable hypothesis is that Gödelian information isn’t processed, but immediately recognised by the human brain.

So, this is indeed a book which provides a very different way of thinking about the way the brain works. It has given me plenty to think about. But I will need to revisit the book repeatedly to fully grasp everything it has to offer.
The True Creator of Everything was courtesy of Yale University Press
Profile Image for Tavo.
138 reviews
September 20, 2022
The author is knowledgable, that's a fact. He did plenty of research on many topics. However, he is trying to cover way too much field. I admire his work on Brain Computer Interfaces and his way of connecting his ideas on neuroscience with other fields, but can't ignore the fact he is pushing his agenda on the reader.

Although I do agree with him on most of the topics outside of neuroscience, which is about 3/4 of the book, I did feel that he tried to convince me that his theory IS the theory of everything and that previous philosophers and scientists have been trying to convey his idea but not using his terms. He could have finished the book before telling the history of science since the hunter-gatherer times. I understand he wanted to make a point but there was no need to put the reader through such a long chapter only to deliver his idea in 1 final paragraph.

I do want to give it a 4 star rating for his enlightening ideas during the first part of the book, but those last 2 chapters of rant were really unexpected specially coming from a neurobiologist.
Profile Image for Corvus.
735 reviews270 followers
September 2, 2021
Great and intriguing concept that started off ok, but has too many archaic thought processes. Very very into repeating that the brain is a computer like he invented the idea. Lots of questionable evo psych.

Also, the usual "humans are so amazing and exceptional unlike these other animals, but here's all my horrific research where I utilize data from other animals as my primary source regarding humans." I gave up when we got to his proud assertion that he has a long career in animal cruelty (brain surgeries and implanting electrodes, testing various behaviors in distressing conditions, then chopping them up.) Very common practice in nonhuman neuroscience, I know, but I should have googled this dude first. I don't give animal abusers my time.

Also, the way he name drops all his super cool buds is kinda cringe.
Profile Image for Dan Graser.
Author 4 books119 followers
November 1, 2020
It feels a bit absurd to review a book like this as I am in no way an expert on the subject area. Also, this is a theory that is far from mainstream in the field of neuroscience and in the scientific community more broadly and thus, not being a scientist myself, I can't really comment on the veracity of many of the claims made here and there are many. If this would be your first introduction to relativistic brain theory then I would recommend a little pre-research before delving into this book as you will likely get lost in the amount of data and also new terminology surrounding this notion.

As a launching point, the authors offer this eureka! type thought that spurred the development of this work:
"Living is all about dissipating energy in order to embed information into organic matter."

This is refined later into the notion of:
"In an open, living system, energy dissipation allows information to be physically embedded into organic matter."

Turning the discussion of the brain away from the idea of an ever more complex Turing machine, the authors delve into the concept of Brainets and how this is not only at the center of our social endeavors but also forms the necessary lense through which our construction of cosmology has occurred. I do feel like there was an unnecessary amount of going back to the beginning sort of contextualization and there is a rant-like quality to two of the latter chapters. However, the summary Epilogue is the most lucid writing found in the book and I genuinely wish the language around this maddeningly impenetrable subject (ironically so) were just as clear as the language found only in the epilogue. This is an interesting read but really required me to pause and do several bouts of outside research, just to gain the limited understanding of it with which I now leave the book.
71 reviews
May 27, 2021
The first part of this book is really fascinating, but it kind of loses its threads at the end. The author leaves behind the discussion of neurobiology for an extended discourse on politics and society, which mainly has the effect of making the book feel much less original.
Profile Image for Mariam24.
1 review
September 19, 2020
This book requires you a neurobiological backgound knowledge to be able to internalize the ideas that the author wants to convey, (I do not want to imagine if I did not have it!) Even so there are many sections in which the ideas branch out impressively and the intended conclusions are modified at the end of certain paragraphs.

In general, it takes the current theories of neuroscience a little further, because it is approached from a less schematic point of view, especially because the author uses other elements or different fields of history, philosophy, art, metaphysics, psychology, human behavior, biology, neural networks, transhumanism, artificial intelligence, etc. and reaches numerous deductions through extensive reviews of experiments and most importantly ... observation.

Many uncertainties that inaugurate some chapters are the development of dilemmas already described in history and I am sure that some questions have already passed through our minds when we see them reflected in the day-to-day lives of our surrenders. The brain can be compared with a computer system but never equaled, starting from the simple fact that the processing is not mathematically perfect, but rather abstract and executes the Gödelian method without processing it ... (I don't know how to explain myself ...)


It caught my attention when it mentioned the study that showed a larger size of the hippocampi in London taxi drivers ... and I start to think that at the speed that the technologies are developing and made our lives easier with an access to immediate information have annulled all the search process that is part of the consolidation of our memories... unfortunately that meticulous evolution to which we have arrived will regress notably, or perhaps there will come a time when having a stunted hippocampus will be ... normal?

The greatest achievement of our brains is definitely its adaptability to changes, its ability to learn and evolve according to the circumstances and rolling needs that gave rise to an artificial intelligence system incomparable with any other and that gap between the truth and the prove is the real challenge. No algorithm can be compared with the dynamics of the organic brain, but once again it is emphasize that experimental science is the way to new horizonts.

At the end of it, it raises more questions than answers, one that came to my mind if mirror neurons play a role in the brain "learning" to generate new pathways of cerebral activity spread, diseases or new skills?

Favorite phrase: After a singular explosive that have rise to cosmos, light finally escaped until it encountered someone who could give some meaning to it all. (the importance of a good observing eye that interprets or is capable of seeking an interpretation ...)

It's a good book because it makes you think and in many moments it reminded me of Sapiens ...
Profile Image for Carla Parreira .
1,948 reviews4 followers
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May 6, 2025
O livro explora de forma fascinante a relação entre o cérebro humano e a construção do universo que conhecemos. O autor discute a ideia de que o cérebro humano é o verdadeiro criador de tudo, pois é através dele que experimentamos e interpretamos o mundo ao nosso redor. Ele explora como nossas percepções, emoções e pensamentos moldam nossa compreensão do universo e como isso influencia nossa interação com ele. O livro aborda a importância da neurociência e da tecnologia para expandir nossas capacidades cerebrais, também explora como a interface cérebro-máquina pode permitir que pessoas com deficiências físicas recuperem suas habilidades motoras. De fato essas tecnologias podem abrir portas para aprimorar nossas habilidades cognitivas e sensoriais. O autor também destaca a importância da colaboração e do trabalho em equipe para ampliar nossas conquistas como sociedade. Ele argumenta que, assim como o cérebro humano é formado por bilhões de neurônios que trabalham juntos, nós também podemos alcançar grandes avanços quando nos unimos e compartilhamos conhecimento.
Partes que destaquei:

1. No início do livro, o autor faz a seguinte declaração: "O cérebro humano é a peça-chave para entender a origem da vida, da consciência e da inteligência. Ele é um mistério que nos permite explorar o universo e descobrir o significado da nossa existência."

2. A importância da neurociência e da tecnologia para a compreensão do cérebro: "A revolução científica nas ciências da vida e na alta tecnologia nos permite explorar o cérebro com um nível de detalhe nunca antes visto, permitindo-nos compreender como ele funciona e como ele nos fez serem seres humanos únicos e extraordinários."

3. A complexidade do cérebro humano e sua conexão com o universo: "O cérebro é um sistema complexo de milhões de células neuronais interconectadas, que, quando funcionam em conjunto, criam a consciência, a percepção, a emoção e a inteligência. Um universo de energia e informação, o cérebro é o meio pelo qual nos movemos por este mundo e nos permite explorar e compreender o universo que nos envolve."

4. A capacidade do cérebro humano para criar e imaginar: "O cérebro é a fonte da criatividade e da imaginação. É ação de nossos neurônios que nos dão a capacidade de visualizar, conceber e criar coisas que não existem ainda nas mãos. É este poder de criação que nos permite ultrapassar as fronteiras do nosso mundo físico e navegar por um universo de possibilidades infinitas."

5. A importância de proteger e compreender esse "verdadeiro criador de tudo": "É nosso dever compreender o cérebro e o seu papel na construção do universo como nós o conhecemos. Só assim, poderemos proteger esse imensamente valioso mistério e garantir a sobrevivência e o desenvolvimento do ser humano neste planeta que ele ajudou a criar."
Profile Image for Richard Thompson.
2,860 reviews167 followers
January 18, 2025
I enjoy speculative theories about the brain and consciousness. I find Daniel Dennett's writings to be intriguing even when he is way out on a limb. Not so much with this one. Mr. Nicolelis is a legitimate credentialed brain scientist, so I hoped for more. His academic writing can't be this sloppy or he would never be published, and he would never have become a full professor at Duke, a highly respected university. I understand that popular books by academics often have to be a little hand wavy, but the core connections back to hard science should be accurate. I didn't feel that here, particularly when the book goes into analogies to relativity and quantum physics, which seemed misconceived to me. Of course our sense impressions of the world are mediated by our brains and bodies so that they are never a completely accurate representation of the world. Philosophers figured that one out a long time ago. But beyond that, I had a lot of difficulty in buying into Mr. Nicolelis's theories. It made me think of William James' classic essay, "The Will To Believe" - if you start with a live proposition, belief can follow, but Mr. Nicolelis lost me early on so most of the rest of it became blah, blah, blah.
1 review
February 11, 2022
There are some nice facts about recent research on the brain. However, the main thesis is unconvincing. What does the brain-centric view of the universe exactly mean? Whether or not there exists an objective reality outside our brains is a philosophical question, not a scientific one.

The closest Nicolelis comes to testable predictions is when he explains how our basic concepts of space and time are subjective. If we met aliens, should they have different concepts? Not so fast: the brain is the product of evolution by natural selection, and therefore so are our concepts. The aliens, having evolved in the same universe, subject to comparable evolutionary forces, might well have ended up with similar concepts.

Finding aliens with the same concepts would not disprove the thesis. Finding aliens with different concepts might possibly prove it. But such aliens would be so alien that we could probably not find them, let alone communicate with them...
Profile Image for Chris Geggis.
60 reviews2 followers
July 1, 2020
I'm dinging one star here for the relativistic brain theory. I don't believe that one picotesla would have any effect on brain function. The only evidence presented seemed to be that it could, so it probably does. I would say that it probably does not. If one picotesla is transmitting usable information, then what is the receiver of that information, and how is it utilized? I was left with those questions and remain extremely skeptical. I did think the rest of the book was worthwhile. It was interesting and engaging and provided sufficient believable evidence for the rest of the concepts to warrant a positive review. I can recommend it, if you're interested in this subject.
Profile Image for Felix Delong.
246 reviews10 followers
April 25, 2021
I guess that with AI resolving the protein folding problem half of the books premises are void now. Theory is interesting, but stands on very shaky base. For example, even though the author quite clearly shows that he knows and understands the quantum mechanics, he still claims that things can be "analog" ie - infinitely smooth, which is impossible in a quantized world. This not only invalidates the entire concept of "Godelian information" as nothing truly can be "analog" in this sense, but it also seems like the author is kinda cherry picking his arguments as he seems fit. This also includes the political agenda... would not recommend.
Profile Image for Jan.
235 reviews5 followers
November 28, 2020
At its dullest during the lengthy polemics against the concept of artificial intelligence and the insidious effects of technology on the brain... or maybe it was the unwelcome dips into Jungian concepts. It would have been more interesting if all of that had been ditched and the book started with the premise of the brain creating the universe and really dove into that wacky but intriguing premise.
Profile Image for Ogi Ogas.
Author 11 books118 followers
September 15, 2023
My ratings of books on Goodreads are solely a crude ranking of their utility to me, and not an evaluation of literary merit, entertainment value, social importance, humor, insightfulness, scientific accuracy, creative vigor, suspensefulness of plot, depth of characters, vitality of theme, excitement of climax, satisfaction of ending, or any other combination of dimensions of value which we are expected to boil down through some fabulous alchemy into a single digit.
27 reviews3 followers
February 2, 2025
Livro interessante mas por vezes enrolado sem necessidade. Alguns capítulos sobre como os experimentos são realizados poderiam ser cortados para deixar o livro mais direto. Afinal, o livro é sobre o cérebro e não sobre como realizar experimentos em ratos de laboratório.

O capítulo sobre IA foi muito bom, trazendo um tema de relevância e unindo com os temas do livro.

De modo geral, bom livro. Se perde nos aspectos muito técnicos em alguns momentos mas traz boas reflexões.
Profile Image for Paige Ovanisian.
191 reviews15 followers
Read
February 5, 2020
DNF @ 5%

I am SO interested in this topic, but the copy I received is so badly formatted that it's painful to read. I must put it down for now, but am interested in the prospect of reading a correctly formatted copy.

eARC provided by Yale University Press via NetGalley in exchange for an honest review. RTC!
Profile Image for David.
725 reviews15 followers
April 4, 2022
This book provides additional perspectives to the thesis that our brains create our reality (see The Case Against Reality: Why Evolution Hid the Truth from Our Eyes by Donald Hoffman).

It is a technically-dense book and is not an easy read. However, if you can hack through it, you will find many fascinating concepts and theories from a neuroscientist's point of view.
Profile Image for Cristie Underwood.
2,270 reviews64 followers
January 29, 2020
This was a very detailed book that I just couldn't get into. I had a hard time understanding some of the concepts the author writes about. I give it 3 stars since it is a genre I typically do not read.
Profile Image for Wasim Shebli.
Author 1 book
July 29, 2025
O livro “O verdadeiro criador de tudo” é uma jornada de alegria no mundo intelectual, onde o leitor pode viajar no navio da sua mente, enxergando pelas visões histórica, artística e científica a milagre do cérebro humano.
Recomendo.
Profile Image for Mark.
81 reviews4 followers
September 5, 2021
Nicolelis is not a very good writer for a general audience. This starts off interesting but gets boring pretty quickly.
Profile Image for Andre Ceron.
73 reviews
March 10, 2023
Uma passagem pelas teorias do grande Nicolelis, pinto final da sua trilogia, a leitura é um desafio pois paradigmas são tratados de uma forma diferente…
Vale cada página.
Profile Image for GONZA.
7,367 reviews124 followers
January 18, 2020
Another "different" book on the brain, but this time it is about the way our brain shaped the world around us, plus some other interesting insights about AI and computers.This one is also a not so easy book, but even if you are not expert on the subject, the whole concepts are really well explained and gave me a lot of food for thoughts.

Un altro libro "diverso" sul cervello, che racconta il modo in cui il cervello stesso ha "forgiato" il mondo intorno a noi, piú alcuni interessanti insights sull'intelligenza artificiale e i supercomputer. Anche questo non é un libro facile, ma anche per i non esperti sull'argomento, i concetti sono ben spiegati e soprattutto fanno riflettere parecchio.

THANKS NETGALLEY FOR THE PREVIEW!
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