This is a solid ending to the ICE (Intrusive Cosmic Entities) trilogy. Once again, Dr. Laura Fanning and Rick Hayden are on the case of alien happenings in the world. It involves a substance called melis (i.e. slime) that has affected a group of unrelated people in certain ways. They all end up in a central location due to the influence of Dr. Stahlman. All of this begins suspiciously like the first X-Men movie that I wondered a bit about the book. However, F. Paul Wilson would have realized this, too, so I stopped worrying, and just enjoyed the story.
The science fiction aspect of this is a lot of fun. Wilson has come up with a truly sleazy and evil villain along with some more complex characters who fill both good and bad roles in the story. The "nadany" and their attributes are all very interesting characters, although I will admit I had trouble telling everyone apart. The plot includes some interesting twists to it, and F. Paul Wilson, as far as I can tell, is incapable of writing an unentertaining book. His imagination and ideas really seem to have no limit.
I enjoyed the Laura/Rick romance, which has been developing since the first book, "The God Gene" and goes through some twists and turns, rather than a simple increasing love that just mounts throughout the trilogy. The one aspect that I didn't like that much was the backstory of the "Anomaly" which was quite vague. Exactly where it came from, how it appeared, and where it ended up is all quite vague. As a result, the ending of the book seemed more abrupt than usual for a Wilson novel. That being said, there is apparently a lot of melis still out there, so perhaps F. Paul Wilson has plans for a fourth Laura/Rick novel. If he does, I will be reading it.