Recommended for those looking to starting creating GUIs using Python. The module used, wxPython, works on all three major platforms. The book also has a chapter on creating standalone exe out of applications created.
This is not suited for beginners to Python though - you'd need to be at least intermediate programmer as well as be comfortable with classes in Python. Some chapters, especially in second half of the book, can be skipped or glanced over if it isn't a topic you are interested in. As with any new skill, this needs time and patience - I'd also advice to type all code snippets instead of copy paste. Having some app in mind to implement will go a long way in speeding up the learning process.