I almost feel like I should split this review in half. One half would be for the game itself, which I think is a five-star experience that does a really credible job of balancing storytelling, the various Trek series, characterization, playability, and crunch-vs-fluff in a way that really, really works. The focus on character, story resolution, the give-and-take of the narrator working with the players even when things are going against the players? It all makes for a great experience, and a very Trek one. It becomes even more rewarding if you also have the Tricorder Rules Digest, which transforms the Character progression into something far, far more intuitive, focused on role-playing, (and doing away with the "nominate" someone mechanic which I loathe on behalf of gaming introverts). It's great. We're loving it. My two groups continue to challenge me as a narrator on an ongoing basis, and we're having a great time.
The other half of the review, however, is for the book itself, which would be—alas—a three-star experience. I get the desire to make the book look Trek-ish, but if you've got even a slight visual impairment, this book is a nightmare to peruse (dark amber or purple italic font on black, really?), and even if you do have 20/20 vision, good luck using the index to find, well, almost anything. At one point, I was trying to remember what Escalation cost meant for equipment—I was pretty sure it was adding to threat—so I checked the index and it sent me to page 312, where it talks about about NPCs with Escalation abilities, which is similar, but not what I was looking for. So I re-read the entire sub-chapter on Weapons, Gear, and Other Items, where the table lists "Escalation" and/or "Opportunity" under the cost heading, but nowhere in the chapter explains what they mean, even though it breaks down all the other qualities listed on the chart. Eventually I went back two sub-chapters to the introduction on stuff and found it, but why in the world would that version of Escalation not be in the index? Thats just one example, but the entire process of learning the game was like this, with much flipping back-and-forth, post-its, and making notes to myself. Worse, the Index wastes space on the fluff. Did you want to find the spot where there's a log-entry from a character? That's listed in the index—but the part where the explains how base energy weapon damage is calculated... isn't in the index.
If I can go back to the physical design choice, the black pages are also glossy, not matte, so even when you're reading the white font, you have to angle the damn book out of the way of a light source. (I get they wanted it to look like LCARS, but remember the Last Unicorn Games Trek game? You so didn't need to go this far to give the Trek feel. Readability is better, I promise.)
Ultimately, I obviously think this game is worthwhile and we are loving playing it, but the shortfalls of the layout of the rulebook are a huge (and ableist) frustration. Originally, I ended up watching play-through videos on the Modiphious Youtube channel, and many times had "a-ha!" moments, so I'd suggest that as a first step, and then read (and prepare to re-read). I backed this when it was first made, but only got the core book physically, the rest digitally, and think the narrator's screen would be worth picking up just for access to all the various "here's what you can do on your turn" panels for the stations on the Bridge and having the information not-scattered in the book for the narrator.
Since my campaigns both picked up speed, I also eventually purchased the Tricorder boxed set and the Rules Digest has everything you need to play, in legible dark-on-white font, and while it's all through a TOS lens, the update to character progression and the presentation and a much more useful index would honestly lead me to suggest any players pick up the Rules Digest rather than the Core Rulebook.
That said? My two groups have been playing this for a year now, and loving it, which is ultimately the point, and why I ended up deciding on four stars.