Mother Knows Best is a well written medical + domestic thriller set in New York State about the lengths two very different women to achieve their heart’s desire using groundbreaking reproductive technology. It was a quick easy read and I enjoyed it, despite the very predictable plot twists and overly convenient ending. I had not come across this author before but would be open to reading more of her work.
Science journalist Claire has been hiding away in the country for eleven years, terrified of the day her nemesis, Jillian Hendricks, will come for her daughter, Abby, and reveal her dark secret - that Abby is the world’s first three-parent child. Conceived in an illegal experiment by IVF, Abby is the result of a new technique, designed to prevent the transmission of the damaged mitochondrial DNA that killed Claire’s first son, Colton, leaving her emotionally shattered and desperate for another baby, but only if it will be healthy. The reproductive specialist, Robert Nash, only wants to help carriers to safely become parents, but his manipulative assistant Jilly sees Abby’s birth as a route to fame, fortune and a relationship with a handsome doctor, so when her plan goes awry and she is left to take the fall, she plans her revenge...
Told in first person present by Claire and Jillian, both in the past and today, and 11 year old Abby now, this was both a strength of the narrative as we get to witness the same situation from three very different viewpoints, but meant I had very little sympathy for any of them as both adults are monstrously selfish, as well as reckless and idiotic - and Abby is not much better. Each does whatever she wants with no regard for the consequences for anyone else, then will blithely lie to get out of trouble.
The author has framed the medical discovery (which is real, although I don’t know how far the technology has been used to date in humans) as a breakthrough unreasonably stifled by conservative American moral concerns, thereby leading to unnecessary suffering. Personally, while I have sympathy for affected families, rules and close monitoring are there for a reason, and the way the trio go about creating Abby is unforgivable.
Of course it all turns out fine for the purposes of a (spoiler alert) happy ending but it does not excuse what they did and the outcome could’ve been very different. No one has a right to a baby especially not when the process is driven by such unethical reasons. I don’t think you need any knowledge of genetics or medicine - or even to understand what mitochondria are, to enjoy this, as the author does an excellent job of explaining the process without extraneous or boring details, but educating readers about medical developments which we are sure to hear more about in the future.
The build up of tension was very well done, as we doubt Claire’s sanity and wonder exactly how far the deranged Jilly will go when she finally turns up. I found many of the characters’ actions to be completely implausible, but if you suspend disbelief and go along for the ride, and are happy to accept the highly contrived ending, this is a good read. I was going to round my 3.5 down for the FPP but am feeling generous so 4 stars it is. My thanks to NetGalley and the publisher for the arc which allowed me to give an honest review, and apologies for missing the publication deadline which was last week.