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Mayo Clinic on Digestive Health: How to Prevent and Treat Common Stomach and Gut Problems
If digestive problems are some of the most common reasons why people seek medical care, why do the majority of Americans know so little about their causes and treatment options? Mayo Clinic on Digestive Health is the fundamental guide for diagnosing, managing, and treating common digestive issues.
Every year, millions of Americans seek medical help for painful digestive health issues. Heartburn, irritable bowel syndrome, ulcers, bloating, diarrhea, and constipation are just a few of the most common offenders. But did you know simple, everyday matters, like eating habits, physical activity, stress, and certain medications, can all cause digestive issues? If you’re experiencing symptoms of an unhealthy gut, your stomach may be sending you a warning sign.
In Mayo Clinic on Digestive Health, the gastroenterologists at Mayo Clinic dive into everything there is to know about digestive health. From explaining the ins and outs of gut microbiome—like why guts “go bad” and how you can improve your gut’s health—to outlining certain tests that help diagnose common digestive issues, this newly revised manual provides a constructive guide for understanding stomach and gut problems.
Additionally, this book gives invaluable tips for diagnosing, treating, and preventing some of the most common digestive conditions and diseases affecting Americans today, like Crohn’s disease, diverticular disease, colorectal cancer, gallbladder disease, ulcers, GERD, celiac disease, and other food intolerances.
Now with more than 300 pages of revised content following the latest medical research, the Mayo Clinic on Digestive Health will help you learn how to spot the symptoms of these common—and not so common—digestive issues.
Every year, millions of Americans seek medical help for painful digestive health issues. Heartburn, irritable bowel syndrome, ulcers, bloating, diarrhea, and constipation are just a few of the most common offenders. But did you know simple, everyday matters, like eating habits, physical activity, stress, and certain medications, can all cause digestive issues? If you’re experiencing symptoms of an unhealthy gut, your stomach may be sending you a warning sign.
In Mayo Clinic on Digestive Health, the gastroenterologists at Mayo Clinic dive into everything there is to know about digestive health. From explaining the ins and outs of gut microbiome—like why guts “go bad” and how you can improve your gut’s health—to outlining certain tests that help diagnose common digestive issues, this newly revised manual provides a constructive guide for understanding stomach and gut problems.
Additionally, this book gives invaluable tips for diagnosing, treating, and preventing some of the most common digestive conditions and diseases affecting Americans today, like Crohn’s disease, diverticular disease, colorectal cancer, gallbladder disease, ulcers, GERD, celiac disease, and other food intolerances.
Now with more than 300 pages of revised content following the latest medical research, the Mayo Clinic on Digestive Health will help you learn how to spot the symptoms of these common—and not so common—digestive issues.
328 pages, Paperback
Published January 14, 2020
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Displaying 1 - 10 of 10 reviews
October 20, 2023
‘The Mayo Clinic on Digestive Health’ is an authoritative guide on digestive issues and practical tips for maintaining optimal health.
With approximately 40% of the global population grappling with chronic gastrointestinal problems, ranging from heartburn to irritable bowel syndrome, there is a critical need to shed light on the intricate web of factors influencing these concerns. Often rooted in elements such as dietary patterns, stress levels, medication use, and physical activity, digestive issues serve as potential indicators of deeper underlying matters within the gut.
This review focuses on the book ‘Mayo Clinic on Digestive Health’ authored by Sahil Khanna, which directly addresses the prevalent issue of digestive illnesses. As we navigate the contents of this book, we will explore its insights, guidance, and potential to illuminate the path toward better gastrointestinal well-being.
Author’s background
Sahil Khanna, M.B.B.S., holds the position of a gastroenterologist and internist at Mayo Clinic located in Rochester, Minnesota.
Within the Division of Gastroenterology and Hepatology, he leads the Comprehensive Gastroenterology Interest Group. Additionally, Dr. Khanna is an associate professor of medicine at Mayo Clinic College of Medicine. His research is centred around various areas including epidemiology, faecal microbiota transplantation, microbiome studies, and novel treatments and outcomes related to Clostridium difficile (C. diff.) infection. Dr. Khanna’s contributions have been acknowledged through multiple accolades such as the Miles and Shirley Fiterman Award, the Mayo Brothers Distinguished Fellowship Award, and the Most Distinguished Resident Physician Award by the American Association of Physicians of Indian Origin. He is currently serving as a fellow for the American College of Gastroenterology.
What is the book about?
‘Mayo Clinic on Digestive Health’ offers readers a clear and comprehensive exploration of the functioning of the digestive system. While the process of digestion may appear straightforward – intake, breakdown, absorption, and elimination – the reality is that the digestive system is a remarkably intricate network of organs that collaboratively process and transform food into vital nutrients essential for well-being.
Amidst this complexity, disruptions can arise, leading to a range of digestive issues. In its fourth edition, the book addresses an array of these issues, encompassing symptoms, causes, diagnostic methodologies, treatment choices, and even proactive measures for prevention. Whether you are struggling with temporary discomfort from common problems like heartburn, diarrhoea, constipation, or gas, or facing more pervasive conditions such as gastroesophageal reflux disease, peptic ulcers, gallstones, Crohn’s disease, or celiac disease, the book caters to a broad spectrum of readers seeking answers.
The book recognises the burgeoning understanding, early detection, and treatment options for various digestive ailments. It particularly highlights the emerging comprehension of the profound influence of the gut on overall health, particularly the pivotal role played by gut bacteria. This intricate interplay extends to interactions with other bodily systems, presenting an interconnected web of health.
Particularly concerning dietary choices, ‘Mayo Clinic on Digestive Health’ equips readers with accurate insights to make informed decisions. By contextualising the essentials of maintaining a healthy digestive system and outlining approaches to combat disease, the book serves as a valuable resource for those navigating the complexities of digestive health.
Three key takeaways from ‘Mayo Clinic on Digestive Health’
1. Your gut matters
The significance of a healthy gut cannot be overstated, as it directly impacts overall well-being. Digestion, a vital bodily function, transforms ingested food into essential nutrients that fuel growth, repair, and maintenance. This intricate process involves breaking down food components and chemically altering them for absorption into the bloodstream, while waste is eliminated. Digestive juices and mechanical actions within the mouth, stomach, and intestines collaborate to facilitate this process.
However, disruptions within this complex system can occur, leading to various signs and symptoms that signal underlying issues. Heartburn, cramps, bloating, diarrhoea, and other distressing symptoms serve as warning signals, indicating that the digestive system is not functioning optimally.
The author emphasises that we should not normalise these problems and resort to over-the-counter drugs to alleviate some of the symptoms. 70% of your immune system resides in the gut, which means that if your gut suffers, it can make you more susceptible not only to infections but also to various chronic diseases.
2. You thrive when your microbiome thrives
The gut microbiome plays a crucial role in overall health, encompassing the diverse microorganisms that inhabit the digestive system and their genetic components. This ecosystem varies between individuals and is influenced by factors such as birth methods, breastfeeding, diet, and ageing. Roughly 100 trillion gut microorganisms, consisting of various bacterial species, contribute to functions like digestion, nutrient absorption, metabolism regulation, and immune system modulation.
An imbalance in gut microbiota, known as dysbiosis, can result from factors like diet. Westernised diets rich in fast foods and sugars, while low in fibre, fruits, and vegetables, have been linked to an increased incidence of diseases such as obesity, cancer, and inflammatory conditions. Dietary choices, including excessive consumption of saturated fats and artificial sweeteners, can alter gut microbial composition, leading to inflammation and potential health issues. Conversely, plant-based, high-fibre diets like the Mediterranean diet support gut diversity and health. Understanding the dynamic interplay between the gut microbiome and various lifestyle factors underscores the importance of maintaining a balanced and nourishing diet for overall well-being.
3. Constipation is more than an inconvenience and can lead to serious complications
The book deals with symptoms and treatment strategies of various digestive diseases. In this review, we will take a look at a very common, yet overlooked condition – constipation. Chronic constipation affects a significant portion of adults, particularly women and older individuals. Severe cases can hinder daily life and social interactions, making medical attention crucial.
Several factors can cause constipation, including dietary and lifestyle imbalances, irritable bowel syndrome (IBS), pelvic floor dysfunction, medications, slow transit, and structural issues. Making small changes can be beneficial: increasing fibre intake, staying hydrated, exercising regularly, adhering to a bowel routine, and listening to your body’s urges.
Ignoring constipation can lead to complications like haemorrhoids and anal fissures. Hemorrhoids and anal fissures can lead to complications such as bleeding, pain, and infection, which can significantly impair a person’s quality of life and require medical intervention. What is more, constipation can affect the health of the thyroid gland which can lead to hormonal imbalance.
Strengths and weaknesses, according to readers’ reviews
Strengths:
• Provides beneficial advice from a reputable source, being a Mayo Clinic publication.
• Offers practical advice and recipes for healthy digestion.
• Well-written with practical advice that proves highly helpful.
Weaknesses:
• The content of the book appears rather dry and could be enhanced by incorporating success stories from the author’s patients.
Best quotes from ‘Mayo Clinic on Digestive Health’
“Good health and a healthy gut go hand in hand. Digestion is one of the critical functions your body must perform in order to survive and thrive. The food you eat provides necessary nutrients that supply your cells with sustenance and energy so your body can develop, repair and maintain itself.”
“More than 60 million Americans experience heartburn at least once a month, and more than 15 million may have heartburn daily.”
“What you put on your plate has a lot to do with good digestion. But it’s not only what you eat that’s important. How much you eat, and the manner in which you eat – relaxed or hurried, focused or distracted – also play key roles. Your daily food choices and eating habits go a long way toward keeping your digestive system strong and healthy.”
Final takeaway
‘Mayo Clinic on Digestive Health’ serves as a comprehensive guide to navigating the complexities of digestive well-being, offering valuable insights into maintaining a healthy gut. Authored by Dr. Sahil Khanna, a distinguished gastroenterologist from Mayo Clinic, the book covers a wide range of digestive issues and provides practical solutions. With a focus on the intricate interplay between diet, lifestyle, and the gut microbiome, the book empowers readers to make informed choices for their health.
This book is recommended for anyone looking to enhance their knowledge of digestive health and make informed decisions regarding their well-being.
With approximately 40% of the global population grappling with chronic gastrointestinal problems, ranging from heartburn to irritable bowel syndrome, there is a critical need to shed light on the intricate web of factors influencing these concerns. Often rooted in elements such as dietary patterns, stress levels, medication use, and physical activity, digestive issues serve as potential indicators of deeper underlying matters within the gut.
This review focuses on the book ‘Mayo Clinic on Digestive Health’ authored by Sahil Khanna, which directly addresses the prevalent issue of digestive illnesses. As we navigate the contents of this book, we will explore its insights, guidance, and potential to illuminate the path toward better gastrointestinal well-being.
Author’s background
Sahil Khanna, M.B.B.S., holds the position of a gastroenterologist and internist at Mayo Clinic located in Rochester, Minnesota.
Within the Division of Gastroenterology and Hepatology, he leads the Comprehensive Gastroenterology Interest Group. Additionally, Dr. Khanna is an associate professor of medicine at Mayo Clinic College of Medicine. His research is centred around various areas including epidemiology, faecal microbiota transplantation, microbiome studies, and novel treatments and outcomes related to Clostridium difficile (C. diff.) infection. Dr. Khanna’s contributions have been acknowledged through multiple accolades such as the Miles and Shirley Fiterman Award, the Mayo Brothers Distinguished Fellowship Award, and the Most Distinguished Resident Physician Award by the American Association of Physicians of Indian Origin. He is currently serving as a fellow for the American College of Gastroenterology.
What is the book about?
‘Mayo Clinic on Digestive Health’ offers readers a clear and comprehensive exploration of the functioning of the digestive system. While the process of digestion may appear straightforward – intake, breakdown, absorption, and elimination – the reality is that the digestive system is a remarkably intricate network of organs that collaboratively process and transform food into vital nutrients essential for well-being.
Amidst this complexity, disruptions can arise, leading to a range of digestive issues. In its fourth edition, the book addresses an array of these issues, encompassing symptoms, causes, diagnostic methodologies, treatment choices, and even proactive measures for prevention. Whether you are struggling with temporary discomfort from common problems like heartburn, diarrhoea, constipation, or gas, or facing more pervasive conditions such as gastroesophageal reflux disease, peptic ulcers, gallstones, Crohn’s disease, or celiac disease, the book caters to a broad spectrum of readers seeking answers.
The book recognises the burgeoning understanding, early detection, and treatment options for various digestive ailments. It particularly highlights the emerging comprehension of the profound influence of the gut on overall health, particularly the pivotal role played by gut bacteria. This intricate interplay extends to interactions with other bodily systems, presenting an interconnected web of health.
Particularly concerning dietary choices, ‘Mayo Clinic on Digestive Health’ equips readers with accurate insights to make informed decisions. By contextualising the essentials of maintaining a healthy digestive system and outlining approaches to combat disease, the book serves as a valuable resource for those navigating the complexities of digestive health.
Three key takeaways from ‘Mayo Clinic on Digestive Health’
1. Your gut matters
The significance of a healthy gut cannot be overstated, as it directly impacts overall well-being. Digestion, a vital bodily function, transforms ingested food into essential nutrients that fuel growth, repair, and maintenance. This intricate process involves breaking down food components and chemically altering them for absorption into the bloodstream, while waste is eliminated. Digestive juices and mechanical actions within the mouth, stomach, and intestines collaborate to facilitate this process.
However, disruptions within this complex system can occur, leading to various signs and symptoms that signal underlying issues. Heartburn, cramps, bloating, diarrhoea, and other distressing symptoms serve as warning signals, indicating that the digestive system is not functioning optimally.
The author emphasises that we should not normalise these problems and resort to over-the-counter drugs to alleviate some of the symptoms. 70% of your immune system resides in the gut, which means that if your gut suffers, it can make you more susceptible not only to infections but also to various chronic diseases.
2. You thrive when your microbiome thrives
The gut microbiome plays a crucial role in overall health, encompassing the diverse microorganisms that inhabit the digestive system and their genetic components. This ecosystem varies between individuals and is influenced by factors such as birth methods, breastfeeding, diet, and ageing. Roughly 100 trillion gut microorganisms, consisting of various bacterial species, contribute to functions like digestion, nutrient absorption, metabolism regulation, and immune system modulation.
An imbalance in gut microbiota, known as dysbiosis, can result from factors like diet. Westernised diets rich in fast foods and sugars, while low in fibre, fruits, and vegetables, have been linked to an increased incidence of diseases such as obesity, cancer, and inflammatory conditions. Dietary choices, including excessive consumption of saturated fats and artificial sweeteners, can alter gut microbial composition, leading to inflammation and potential health issues. Conversely, plant-based, high-fibre diets like the Mediterranean diet support gut diversity and health. Understanding the dynamic interplay between the gut microbiome and various lifestyle factors underscores the importance of maintaining a balanced and nourishing diet for overall well-being.
3. Constipation is more than an inconvenience and can lead to serious complications
The book deals with symptoms and treatment strategies of various digestive diseases. In this review, we will take a look at a very common, yet overlooked condition – constipation. Chronic constipation affects a significant portion of adults, particularly women and older individuals. Severe cases can hinder daily life and social interactions, making medical attention crucial.
Several factors can cause constipation, including dietary and lifestyle imbalances, irritable bowel syndrome (IBS), pelvic floor dysfunction, medications, slow transit, and structural issues. Making small changes can be beneficial: increasing fibre intake, staying hydrated, exercising regularly, adhering to a bowel routine, and listening to your body’s urges.
Ignoring constipation can lead to complications like haemorrhoids and anal fissures. Hemorrhoids and anal fissures can lead to complications such as bleeding, pain, and infection, which can significantly impair a person’s quality of life and require medical intervention. What is more, constipation can affect the health of the thyroid gland which can lead to hormonal imbalance.
Strengths and weaknesses, according to readers’ reviews
Strengths:
• Provides beneficial advice from a reputable source, being a Mayo Clinic publication.
• Offers practical advice and recipes for healthy digestion.
• Well-written with practical advice that proves highly helpful.
Weaknesses:
• The content of the book appears rather dry and could be enhanced by incorporating success stories from the author’s patients.
Best quotes from ‘Mayo Clinic on Digestive Health’
“Good health and a healthy gut go hand in hand. Digestion is one of the critical functions your body must perform in order to survive and thrive. The food you eat provides necessary nutrients that supply your cells with sustenance and energy so your body can develop, repair and maintain itself.”
“More than 60 million Americans experience heartburn at least once a month, and more than 15 million may have heartburn daily.”
“What you put on your plate has a lot to do with good digestion. But it’s not only what you eat that’s important. How much you eat, and the manner in which you eat – relaxed or hurried, focused or distracted – also play key roles. Your daily food choices and eating habits go a long way toward keeping your digestive system strong and healthy.”
Final takeaway
‘Mayo Clinic on Digestive Health’ serves as a comprehensive guide to navigating the complexities of digestive well-being, offering valuable insights into maintaining a healthy gut. Authored by Dr. Sahil Khanna, a distinguished gastroenterologist from Mayo Clinic, the book covers a wide range of digestive issues and provides practical solutions. With a focus on the intricate interplay between diet, lifestyle, and the gut microbiome, the book empowers readers to make informed choices for their health.
This book is recommended for anyone looking to enhance their knowledge of digestive health and make informed decisions regarding their well-being.
June 22, 2025
All of this information matches what I had researched back when I had been first looking into eating troubles slightly more than twenty-one years ago. The book has more about some of the other different problems with eating besides the individual one I had picked out of a bag to focus on looking into specifically now. (Or it seemed very close. My memory might have frayed a bit over the span of over 7,500 days.)
I looked into the whole book since each problem has its own quirks and I had the curiosity, and the "spoons" as well. I thought this resource might be a solid foundational work on the subject, but who am I to judge?
I have observed people who have almost each one of the problems this team of authors describe, even running around outside of a hospital setting, and it seemed to me like for those who have difficulties with their digestive systems, the advice of Dr Khanna et al might help more than hurt.
I looked into the whole book since each problem has its own quirks and I had the curiosity, and the "spoons" as well. I thought this resource might be a solid foundational work on the subject, but who am I to judge?
I have observed people who have almost each one of the problems this team of authors describe, even running around outside of a hospital setting, and it seemed to me like for those who have difficulties with their digestive systems, the advice of Dr Khanna et al might help more than hurt.
October 26, 2020
Right level for those without medical knowledge, just trying to find out: what on earth is wrong with me?
Sadly, medical science tells us: stomach pain can be caused by A LOT of different things, just drink water, exercise, meditate, don't drink alcohol or eat fatty foods.
Sadly, medical science tells us: stomach pain can be caused by A LOT of different things, just drink water, exercise, meditate, don't drink alcohol or eat fatty foods.
May 6, 2026
Medical knowledge about the digestive system and how to prevent common gut issues. Very easy to swallow and understand. Layman's terms and very useful for the average person without a medical degree to comprehend.
April 30, 2021
well written with very helpful advice
February 18, 2022
Needed info
I really am glad I bought this book. I have used FOMAP before and needed the refresher course to help mel
I really am glad I bought this book. I have used FOMAP before and needed the refresher course to help mel
November 6, 2025
Kind of boring but good information.
March 10, 2026
Very informative and is written in a way so that individuals who do not have a medical background can understand the material.
June 11, 2026
Good book on your digestive system and how to prevent certain problems
October 12, 2026
Somewhat Informative
I found some of the information very enlightening, but I knew a lot of this stuff already. I ended up skimming through it and skipping parts I already knew.
I found some of the information very enlightening, but I knew a lot of this stuff already. I ended up skimming through it and skipping parts I already knew.
Displaying 1 - 10 of 10 reviews