This book isn't literally about orphan diseases, it's about diseases that scientists and doctors don't really pay much attention to. It talks about all kinds of diseases including Achondroplasia, hemophilia, and autism. This is a book that is great to read when going into the medical field. It explains diseases and gives you a better understanding to what they are and how they are caused. I liked it because I learned so much about diseases that I didn't even know excited.