I wish to extend thanks to NetGalley and Simon & Schuster, Canada, for the ARC of this intense medical thriller by Daniel Kalla. The author is an ER physician in Vancouver, BC., who writes novels with medical themes based on sound scientific knowledge and research. I have been informed by and enjoyed Kalla's previous works and was happy to receive his latest book. There seems to presently be a scarcity of medical thrillers, a genre that is among my favourite. Kalla's novels are always believable and suspenseful.
Lost Immunity is set sometime after the COVID pandemic has ended. It doesn't guess how close or distant in the future its time frame is set. This book was written while the COVID virus was still spreading. Kalla uses his knowledge of life-saving vaccines in the past that saved many lives and ended some varied and dangerous diseases, and the viewpoints of anti-vaxxers who may slow down future efficiency. Medical terms that would have needed explanation a year ago are now known by many people, such as 'asymptomatic carriers' and 'herd immunity.'
The medical practitioners seem authentic, but I failed to engage with the characters despite my strong feeling of suspense and mystery. The story begins with an outbreak of a deadly form of meningitis in the Seattle area. This contagious bacterial infection mainly affects small children and teenagers. Lisa Dyer, Seattle's chief public health officer and her team, learn that this is the same strain of the disease that caused deaths in Iceland six months earlier but now seems to have gone dormant there. They contact Nathan Hall, vice-president of a pharmaceutical company that seems to have a viable vaccine for the disease. However, they have not completed testing it. After much persuading that it is needed immediately to save many young people's lives, they receive a large shipment of the drug, although test trials are not complete.
This risky strategy is opposed by some medical experts, government officials, and anti-vaxxers. The vaccinations seem to be successful in stopping the spread of meningitis and its death toll. A horrible side effect is found among a small number of those vaccinated, throwing the vaccine into disrepute. It looks like someone has hacked into the medical files and deleted information about a person's death following the vaccine. Worse, there may have been contamination of a small number of closely guarded vials of the serum. There is now a rush to find out how a few of the vials were contaminated and causing life-altering side effects, or giving up on the vaccine rollout and letting children and their contacts die in the present meningitis clusters. The pharmaceutical company's reputation is in tatters, and parents are afraid to have their children vaccinated.
Recommended for people who enjoy intense, suspenseful medical mysteries.